steric hindrance
Hemagglutinin Stalk-Reactive Antibodies Interfere with Influenza Virus Neuraminidase Activity by Steric Hindrance
... through steric hindrance on whole virions, adding to the mechanisms of protection mediated by this broadly reactive class of antibodies and providing a mechanism for the previously observed inhibition of ...
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Effects of induced steric hindrance on the dielectric behavior and H bonding in the supercooled liquid and vitreous alcohol
... been replaced by the phenyl group. This introduces a steric hindrance to H bonding without significantly affecting the net dipole moment. Moreover, the 1-phenyl-1-propanol mol- ecule contains an asymmetric ...
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A Monoclonal Antibody Specific for Reovirus Outer-Capsid Protein ς3 Inhibits ς1-Mediated Hemagglutination by Steric Hindrance
... Studies of mechanisms by which antiviral antibodies inhibit viral infectivity can yield an improved understanding of virus structure and replication. Antibodies can neutralize viruses by blocking viral binding to ...
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Steric hindrance in the upper 50 kDa domain of the motor Myo2p leads to cytokinesis defects in fission yeast
... a steric clash between arginine and tyrosine, potentially resulting in instability of the myosin head domain during conformational changes accompanying the actomyosin contraction cycle (Stark et ...the ...
8
Influence of Steric Hindrance on The Antioxidant Activity of Some Schiff Base Ligands And Their Copper(II) Complexes
... to steric crowd, number of free hydroxyl groups and other factors such as stereoselectivity of the radicals or the solubility of these compounds in different testing systems may also affect the capacity of ...
6
Inhibition of Parainfluenza Virus Type 3 and Newcastle Disease Virus Hemagglutinin-Neuraminidase Receptor Binding: Effect of Receptor Avidity and Steric Hindrance at the Inhibitor Binding Sites
... immediate steric clash between the C ␦ methyl group of I175 and the guanidinium moiety of 4-GU-DANA if the ligand were bound in the same conformation as that observed for its complex with the ...this steric ...
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Alpha-Defensin HD5 Inhibits Furin Cleavage of Human Papillomavirus 16 L2 To Block Infection
... via steric hindrance, as our data show that HD5 does not interfere with the interaction between the RG-1 antibody and the epitope on L2 nor does a molar excess of rL2:13–36 rescue viral infection, making L2 ...
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Systematic study of the structural parameters affecting the self assembly of cyclic peptide–poly(ethylene glycol) conjugates
... the steric hindrance caused by grafting a dense brush polymer to a single cyclic peptide, it is highly plausible that this system assembles in very small aggregates, or not at ...
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C60 Bioconjugation with Proteins: Towards a Palette of Carriers for All pH Ranges
... [26]. Steric hindrance and electrostatic repulsion are the key factors determining the stability of the dispersion of carbon nanomaterials-protein complexes in aqueous solutions ...
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Cooperativity in Virus Neutralization by Human Monoclonal Antibodies to Two Adjacent Regions Located at the Amino Terminus of Hepatitis C Virus E2 Glycoprotein
... Having established that both regions induce neutralizing anti- bodies, we performed combined studies to assess antibody coop- erativity. Whether the antibodies induced by these regions are additive, synergistic, or ...
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Effect of Confinement on Chemical Reactions
... Our main findings from these studies are: (1) In the molecular sieving limit, the steric hindrance imposed by the pore walls can cause dramatic changes in the potential energy surface [r] ...
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(3S) 3 Benzyloxymethyl 1,4 dioxane 2,5 dione
... puckering parameters (Cremer & Pople, 1975) are θ = 77.1 (6)° and φ = 320.3 (6)°; the ideal values for the observed screw-boat conformation are θ = 67.5° and φ = 330°. The benzyloxymethyl substituent of the lactide ...
9
Crystal Structure of a Poxvirus-Like Zalpha Domain from Cyprinid Herpesvirus 3
... that steric hindrance between the two monomers comprising the dimer, now located at a fixed distance from the binding site, might interfere with DNA binding ...
7
(E) (25S) 23 Acetyl 5β furost 22 ene 3β,26 diol
... defined geometry (see Experimental). The acetyl group substituting the furostenic atom C23 forms a s-cis α,β-unsaturated ketone system with the E configuration at the C22?C23 double bond. The methyl group C21 is placed ...
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Ph-Metric Study on Determination of Proton- Ligand Stability Constants of Some Substituted Pyrazolines
... It could be seen from above Table -5 that, there is no as such an appreciable change in proton - ligand constant (pK) because steric hindrance effect is compensated due to electron withd[r] ...
6
DNA sequence analysis of artificially evolved ebg enzyme and ebg repressor genes.
... tion is that the 188 to 196 regions of the wild-type ebgR repressor might exclude lactulose and Gal-Ara by steric hindrance, whereas a looser conformation of this region [r] ...
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Alfalfa Mosaic Virus Replicase Proteins P1 and P2 Interact and Colocalize at the Vacuolar Membrane
... The fact that interaction between full-length P1 and P2 was detectable by coimmunoprecipitation but not in the two-hybrid system may be due to steric hindrance caused by the activation o[r] ...
9
Effects of Coating and Stirring on Superparamagnetic Iron Oxide Nanoparticles Size and Magnetic Characteristics
... deposition [9], and, ii- chemical method mainly using co-precipitation technique [18]. The difficulty in the synthesis of ultrafine particles arises from the high surface energy of these systems. The MNPs can be coated ...
8
Structural Effect of Polymers on Their Microvia Filling Performance as Suppressors During the Copper Electroplating
... Then, the reasons for the differences between the two suppressors are investigated in detailed. The results of galvanstatic measurements and cyclic voltammetry demonstrate that the EPE2900 leads to stronger suppression ...
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Dealing with traffic hindrance at Rijkswaterstaat : analysis of the current traffic hindrance approach of Rijkswaterstaat based on stakeholder perception and the changed relation with the market
... Another procurement strategy is the so called best value procurement (BVP). The strategy is characterised as ‘a vision and method for procurement and tendering which puts the performance of market party central and not ...
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