Steroid induced osteonecrosis
Pulsed electromagnetic fields stimulation prevents steroid induced osteonecrosis in rats
... prevent osteonecrosis and revealed satisfactory results ...of steroid-induced ...prevent steroid-induced ...prevent osteonecrosis because several studies have shown that it can ...
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The initial phase of oxidative stress in a steroid induced osteonecrosis rabbit model
... of steroid-induced osteonecrosis, it is necessary to detect oxidative reaction in the bone at its initial ...of steroid-induced oste- ...
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Original Article MiR-140-5p suppresses the adipogenic differentiation of mesenchymal stem cells in rats with steroid-induced osteonecrosis of the femoral head
... with steroid-induced osteonecrosis of the femoral head ...and induced to undergo adipogenic differentiation by inhibiting miRNA-140-5p expression and/or ATRA ...
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Achyranthes bidentata extract exerts osteoprotective effects on steroid induced osteonecrosis of the femoral head in rats by regulating RANKL/RANK/OPG signaling
... Steroid-induced osteonecrosis of the femoral head (ster- oid-induced ONFH) is a serious complication in patients who have received steroids for the treatment of various diseases, including ...
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Autogenous osteochondral graft transplantation for steroid-induced osteonecrosis of the femoral condyle: A report of three young patients
... Steroid-induced osteonecrosis of the femoral condyle is a relatively uncommon condition and its clinical course and established treatment remain controversial, mainly be- cause of the limited number ...
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Original Article Combined effect of tnf-α polymorphisms and hypoxia on steroid-induced osteonecrosis of femoral head
... 2]. Steroid- induced osteonecrosis of the femoral head (SONFH), a non-traumatic ONFH, is often brought about by a long-term or high-dose usage of adrenocortical hormone that is beyond the physical ...
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Protective effects of molecular hydrogen on steroid induced osteonecrosis in rabbits via reducing oxidative stress and apoptosis
... of steroid-induced osteonecrosis ...of steroid-induced ON in animals and ...for steroid-induced ON in an established rabbit ...of steroid-induced ON in ...
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Systemic application of teriparatide for steroid induced osteonecrosis in a rat model
... A great number of studies had shown that the teri- paratide had the potential effect in bone union, spinal fusion and bone defect repair [27, 28]. Moreover, teri- paratide also had been shown to be useful in periodontal ...
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Original Article Ginsenoside Rg1 protects steroid-induced osteonecrosis of the femoral head in rats by suppressing oxidative stress and adipogenesis
... preventing steroid-induced osteo- ...with steroid-induced osteone- crosis of the femoral head ...the steroid-induced ONFH ...the steroid-induced ONFH rats. Rg1 may ...
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Osteogenic effect of bone marrow mesenchymal stem cell-derived exosomes on steroid-induced osteonecrosis of the femoral head
... Steroid-induced femoral head necrosis (SFHN) is a major metabolic disorder that occurs following long-term hormone drug use, which decreases the vascular supply to the femoral head and osteocytes and causes ...
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Genetic polymorphisms in plasminogen activator inhibitor-1 predict susceptibility to steroid-induced osteonecrosis of the femoral head in Chinese population
... Non-traumatic osteonecrosis of femoral head (ONFH) represents an intractable bone disease, pathophysio- logically characterized by progressive collapse of the femoral head because of a disturbance in the supply of ...
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Association of apolipoprotein A5 genetic polymorphisms with steroid-induced osteonecrosis of femoral head in a Chinese Han population
... Osteonecrosis of femoral head (ONFH) is a kind of orthopedic refractory disease that cellular death happens within femoral head owing to damage of blood supply to the anterior-superior-lateral part of the femoral ...
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Association of a polymorphism in PON-1 gene with steroid-induced osteonecrosis of femoral head in Chinese Han population
... To our knowledge, the specific mechanism of steroid- induced ONFH is still unclear. Several hypotheses con- cerning fat embolism, intraosseous hypertension and venostasis, microvascular impair and ...
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A single-nucleotide polymorphism in MMP9 is associated with decreased risk of steroid-induced osteonecrosis of the femoral head
... To our knowledge, the present study provides the first evidence that variation at the rs2274755 locus in the MMP9 gene is associated with a decreased risk of steroid-induced ONFH risk in the northern ...
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The effect of core decompression on local expression of BMP 2, PPAR γ and bone regeneration in the steroid induced femoral head osteonecrosis
... the steroid- induced osteonecrosis with and without lateral decom- pression than that in the normal control animals by western ...the steroid-induced fem- oral head osteonecrosis ...
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Involvement of tumor necrosis factor alpha in steroid-associated osteonecrosis of the femoral head: friend or foe?
... Tumor necrosis factor alpha (TNFα) has been found as a substance that mediates endotoxin-induced necrosis of tumors. It is well known as a cytokine participating in systemic inflammation and acute phase reaction. ...
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Immune response associated with Toll like receptor 4 signaling pathway leads to steroid induced femoral head osteonecrosis
... Possibly, steroid-induced osteonecrosis arises due to the activation of the TLR4 signaling pathway that sets the destructive mechanisms in ...Moreover, steroid-induced ...
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Chicken model of steroid-induced bone marrow adipogenesis using proteome analysis: a preliminary study
... liferation. Steroid-induced adipogenesis increases fat-cell volume and pressure in the marrow, eventually leading to some forms of osteonecrosis of the femoral head ...of ...
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Exosomes Secreted from Human-Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Prevent Osteonecrosis of the Femoral Head by Promoting Angiogenesis
... Stem cell transplantation has been proven to be able to promote angiogenesis in ONFH [7, 8]. However, the potential risks and problems are a major limitation for the possibility of clinical application. Exosomes secreted ...
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Elevated adipogenesis of marrow mesenchymal stem cells during early steroid-associated osteonecrosis development
... is osteonecrosis (ON), that most fre- quently presents in femoral heads and often advances to subchondral bone collapse and needs arthroplasty ...in steroid-associated ON patients ...
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