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Stress granule assembly

Amyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics

Amyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics

... of stress, elevated levels of cytoplasmic FUS were observed in NSC-34 cells expressing FUS R495X, and diffuse cytoplasmic G3BP signal was observed in both FUS R495X and WT ...positive stress granules only ...

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The Leader Protein of Cardioviruses Inhibits Stress Granule Assembly

The Leader Protein of Cardioviruses Inhibits Stress Granule Assembly

... that stress granules assemble in cells infected with Theiler’s murine encephalomyelitis virus (TMEV) mutants carrying alterations in the leader (L) protein, but not in cells infected with wild-type ...TMEV. ...

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Processing Body and Stress Granule Assembly Occur by Independent and Differentially Regulated Pathways in Saccharomyces cerevisiae

Processing Body and Stress Granule Assembly Occur by Independent and Differentially Regulated Pathways in Saccharomyces cerevisiae

... and stress granule assembly in response to a variety of environ- mental cues, including several that can induce both of these RNP ...body assembly in all conditions tested. In contrast, ...

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HIV 1 Gag Blocks Selenite Induced Stress Granule Assembly by Altering the mRNA Cap Binding Complex

HIV 1 Gag Blocks Selenite Induced Stress Granule Assembly by Altering the mRNA Cap Binding Complex

... the assembly of SGs by Ars or pateamine A (PatA) or in cells overexpressing G3BP1/TIAR (5, ...the assembly of noncanonical type II SGs that contain core SG markers (G3BP1, TIA-1, and TIAR) but lack eIF3 ...

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p38 and OGT Sequestration into Viral Inclusion Bodies in Cells Infected with Human Respiratory Syncytial Virus Suppresses MK2 Activities and Stress Granule Assembly

p38 and OGT Sequestration into Viral Inclusion Bodies in Cells Infected with Human Respiratory Syncytial Virus Suppresses MK2 Activities and Stress Granule Assembly

... Hanley et al. also described SGs in the context of RSV infection (30). This study similarly showed that SGs formed in only a small percentage (⬃5%) of cells infected with wild-type RSV, whereas SGs were much more ...

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Doubly Spliced RNA of Hepatitis B Virus Suppresses Viral Transcription via TATA-Binding Protein and Induces Stress Granule Assembly

Doubly Spliced RNA of Hepatitis B Virus Suppresses Viral Transcription via TATA-Binding Protein and Induces Stress Granule Assembly

... expression plasmid, whereas SG assembly was not observed in the cells transfected with the 2.2DS-RNA-deficient HBV G2335A ex- pression plasmid (Fig. 6B). However, the results of our current study do not fully ...

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Chikungunya Virus nsP3 Blocks Stress Granule Assembly by Recruitment of G3BP into Cytoplasmic Foci

Chikungunya Virus nsP3 Blocks Stress Granule Assembly by Recruitment of G3BP into Cytoplasmic Foci

... To investigate the relationship between CHIKV replication and SG formation, Vero cells were transfected with CHIKV repli- con RNA in two independent experiments as described previously (6). Next, at 16 h posttransfection ...

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Endogenous TDP-43, but not FUS, contributes to stress granule assembly via G3BP

Endogenous TDP-43, but not FUS, contributes to stress granule assembly via G3BP

... following stress ex- posure ...oxidative stress in both HeLa and the neuronal-like cell line ...and assembly in the context of acute oxidative ...

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Disruption of Stress Granule Formation by the Multifunctional Cricket Paralysis Virus 1A Protein

Disruption of Stress Granule Formation by the Multifunctional Cricket Paralysis Virus 1A Protein

... inhibit stress granule assembly in HeLa ...cellular stress observed in many eukaryotes ...SG assembly in Drosophila S2 cells, we investigated whether CrPV-1A expression can affect SG ...

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Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics

Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics

... including stress granules. Defects in stress granule homeostasis constitute a cornerstone of ALS/FTLD ...ALS-linked stress granule ...and stress granule ...spontaneous ...

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PARTICLE GROWTH MODELLING AND SIMULATION IN DRUM GRANULATOR-DRYER

PARTICLE GROWTH MODELLING AND SIMULATION IN DRUM GRANULATOR-DRYER

... Starting with min. 23, the flow of slurry is initiated and the “growth and drying” operation begins. The particles are coated by sprayed slurry and dry. The energy required to evaporate moisture is produced by a reaction ...

6

Altered ribostasis: RNA protein granules in degenerative disorders

Altered ribostasis: RNA protein granules in degenerative disorders

... normal assembly of stress granules and be continually disassembled by cellular mechanisms ...since stress granules are highly dynamic (t1/2~30 sec by FRAP; Buchan and Parker, 2009), and prion-like ...

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Induction of Stress Granule-Like Structures in Vesicular Stomatitis Virus-Infected Cells

Induction of Stress Granule-Like Structures in Vesicular Stomatitis Virus-Infected Cells

... the stress granules (SGs) generated in cells trig- gered by heat shock or oxidative stress but do not contain some of the bona fide SG markers, such as eukaryotic initiation factor 3 (eIF3) or eIF4A, or the ...

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The Effect of Cladding Creep on the Initiation of GTRFW

The Effect of Cladding Creep on the Initiation of GTRFW

... contact stress and the hydrostatic pressure from the coolant play important roles in the creep ...the stress relaxation caused by creep, partial slip is first observed around the edge of the ...

6

DEPS 1 promotes P granule assembly and RNA interference in C 
elegans germ cells

DEPS 1 promotes P granule assembly and RNA interference in C elegans germ cells

... deps-1 encodes a novel protein with a serine-rich C-terminal domain of low amino acid complexity (Fig. 2A). DEPS-1 is 45-51% identical to predicted proteins in the closely related nematodes C. briggsae and C. remanei, ...

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Design and structural analysis of conventional lathe for retrofitting

Design and structural analysis of conventional lathe for retrofitting

... Figure 7 Total deformation in static load condition, casting body assembly. Figure 8 Equivalent (von-Mises) stress, casting body assembly[r] ...

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Effect of biozyme and fertility levels on growth, yields,  nutrient uptake, nutrient harvest and physiological efficiency index  of soybean (glycine max l  merrill)

Effect of biozyme and fertility levels on growth, yields, nutrient uptake, nutrient harvest and physiological efficiency index of soybean (glycine max l merrill)

... Biozyme granule +half of recommended ...Biozyme granule + half of recommended NPK were ...Biozyme granule or spray with half of recommended NPK might promoted root proliferation and their ...

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Mammalian Orthoreovirus Factories Modulate Stress Granule Protein Localization by Interaction with G3BP1

Mammalian Orthoreovirus Factories Modulate Stress Granule Protein Localization by Interaction with G3BP1

... Recent evidence has shown that translation occurs in MRV VFs and that the cellular translational machinery, including ribosomes and translation initiation factors, are localized to VFs (29). ␴ NS was shown to interact ...

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Defining the Role of Stress Granules in Innate Immune Suppression by the Herpes Simplex Virus 1 Endoribonuclease VHS

Defining the Role of Stress Granules in Innate Immune Suppression by the Herpes Simplex Virus 1 Endoribonuclease VHS

... termed stress granules (SGs) often accumulate within the ...SG assembly is disrupted by ISRIB, an inhibitor of phosphorylated eIF2 ␣ -mediated translation repression, or depleting SG scaffolding proteins ...

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Regulation and Dynamic Behavior of the Heat Shock Transcription Factor Hsf-1 in C. Elegans

Regulation and Dynamic Behavior of the Heat Shock Transcription Factor Hsf-1 in C. Elegans

... of stress. Under non-stress conditions, HSF-1::GFP was found primarily in the ...nuclear stress granules, including colocalization with markers of active ...HSF-1 stress granules was promoted ...

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