Stress granules (SGs)
The chemotherapeutic agent bortezomib induces the formation of stress granules
... Stress granules (SGs) are cytoplasmic ribonucleopro- tein-containing bodies whose formation is favored by various stress conditions leading to eIF2α phosphoryla- ...these stress agents ...
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Regulated protein aggregation: stress granules and neurodegeneration
... with stress granules ...with SGs and are required for SG formation, just as they are required for other stress processes; these proteins couple SGs to the cytoskeleton and facilitate ...
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Dynamic Interaction of Stress Granules, DDX3X, and IKK-α Mediates Multiple Functions in Hepatitis C Virus Infection
... be stress granules ...DDX3X granules together with SG- associated proteins redistribute and colocalize with HCV core protein around lipid droplets ...to SGs and LDs, consistent with the tight ...
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Rotavirus Infection Induces the Phosphorylation of eIF2α but Prevents the Formation of Stress Granules
... of stress granules (SGs), which are cytoplasmic aggregates of stalled translational preinitiation complexes that accumulate during ...that SGs are sites of mRNA triage at which mRNAs are ...
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Calcineurin Colocalizes with P-Bodies and Stress Granules during Thermal Stress in Cryptococcus neoformans
... to stress, the number of PBs increases as cellular translation is ...inhibited. Stress results in the formation of a second class of RNA aggregates called stress granules (SGs), which ...
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Zika Virus Subverts Stress Granules To Promote and Restrict Viral Gene Expression
... cell stress response by preventing the formation of stress granules (SGs) and modulate viral gene expression by subverting different proteins involved in the stress granule ...of ...
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Stress Granules Regulate Double Stranded RNA Dependent Protein Kinase Activation through a Complex Containing G3BP1 and Caprin1
... ABSTRACT Stress granules (SGs) are dynamic cytoplasmic repositories containing translationally silenced mRNAs that assemble upon cellular ...to stress granules, thereby driving ...
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Stable Formation of Compositionally Unique Stress Granules in Virus-Infected Cells
... for stress granule formation ...to stress granules ...typical SGs. These findings reveal that although poliovirus-induced SGs are dis- tinguishable from oxidative stress-induced ...
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Mammalian Orthoreovirus Particles Induce and Are Recruited into Stress Granules at Early Times Postinfection
... called stress granules (SGs), where they are held in a translationally inactive ...that SGs formed at early times following infection (2 to 6 h postinfection) in a manner dependent on ...
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C-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress
... RNA stress granule proteins [16,17]. Stress granules (SGs) are cytoplasmic sites of stalled mRNA pre-initiation complexes induced by oxidative changes, heat shock or osmotic stress ...
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Modulation of Stress Granules and P Bodies during Dicistrovirus Infection
... of stress granules in Drosophila S2 ...that SGs can be induced in Drosophila S2 cells under oxidative and heat shock stress, stresses that inhibit translation initiation in an eIF2 ␣ ...
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Title: Revisiting the Stress concept in the context of solid tumors prognostic: a role for the Stress Granules?
... Stress granules are membrane less cytoplasmic condensates, visible by conventional and electron microscopy, that were first discovered in 1999 by the laboratory of ...surrounding SGs and the extreme ...
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Stress Granules and P Bodies: An Insight into mRNA Translational Control and Decay
... RNA granules are higher order RNA-protein complexes formed due to protein-protein and protein-RNA ...nutritional stress, oxidative stress, heat shock, unfolded proteins trigger assembly of RNA ...
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Respiratory Syncytial Virus Induces Host RNA Stress Granules To Facilitate Viral Replication
... arsenite-induced stress granules as well ...induced stress granules, as well as RSV inclusion ...identify stress granules ...
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The NS1 Protein of Influenza A Virus Interacts with Cellular Processing Bodies and Stress Granules through RNA-Associated Protein 55 (RAP55) during Virus Infection
... RAP55-associated stress granules and P-bodies during influenza virus ...with stress granules and also suggested to have a function in shuttling mRNAs between P-bodies and stress ...
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MDA5 Localizes to Stress Granules, but This Localization Is Not Required for the Induction of Type I Interferon
... Virus infection can initiate a type I interferon (IFN-␣/) response via activation of the cytosolic RNA sensors retinoic acid-in- ducible gene-I (RIG-I) and melanoma differentiation-associated gene 5 (MDA5). Furthermore, ...
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Stress granules and RNA processing bodies are novel autoantibody targets in systemic sclerosis
... of stress granules and then with 4 % para- formaldehyde solution at room temperature for 15 - minutes followed by blocking and permeabilization with 5 % normal horse serum, ...
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Directly converted patient-specific induced neurons mirror the neuropathology of FUS with disrupted nuclear localization in amyotrophic lateral sclerosis
... the stress granule markers eIF4G (red) in the ...oxidative stress conditions, cytoplasmic FUS-positive inclusion bodies of G504Wfs*12 and R495* mutation co-localized with eIF4G stress granules ...
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Protein Kinases Are Associated with Multiple, Distinct Cytoplasmic Granules in Quiescent Yeast Cells
... RNP granules can also be induced by specific developmental and cell growth ...polar granules in Drosophila melanogaster are produced in the oocyte and serve to specify the germ-cell lineage in the developing ...
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A Stress-Responsive Signaling Network Regulating Pseudohyphal Growth and Ribonucleoprotein Granule Abundance in Saccharomyces cerevisiae
... to stress granules, including proteins in the translation initiation closed-loop complex, such as eIF4G/Tif4631p, or proteins that bind to this complex, such as Pbp1p and ...teinaceous stress granule ...
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