Stress-induced Neuronal Damage
Neurogenesis enhancing effect of sodium ferulate and its role in repair following stress induced neuronal damage
... following stress-induced neuronal ...mild stress (CMS) tests were per- formed to establish rat model of ...mild stress (CMS)-induced depression-like model rats by ...
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Neuroprotective Functions of Alpinia galanga in Forebrain Ischemia Induced Neuronal Damage and Oxidative Insults in Rat Hippocampus
... oxidative stress may be useful in rescuing neuronal cells exposed to ...oxidative stress caused by forebrain ischemia could be assessed by enhancing the cerebral activity of endogenous antioxidant ...
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Effects of dalteparin on structure of hippocampal neurons of rats in chronic stress
... to neuronal death (Maes, 2007; Forlenza, 2006; Sapolsky, ...psychological stress is accompanied by increased plasma level of IL-6 (Zhou, 1993; Kiecolt-Glaser, ...that stress- ful life events lead to ...
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Synergistic effects of amyloid peptides and lead on human neuroblastoma cells
... induces neuronal death is still ...oxidative damage and accumulation of reactive oxygen species (ROS) are ...Oxidative stress, which plays an important role in Aβ-mediated neuronal ...
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Icariin Inhibits Endoplasmic Reticulum Stress-induced Neuronal Apoptosis after Spinal Cord Injury through Modulating the PI3K/AKT Signaling Pathway
... (ER) stress-induced neuronal apoptosis is a crucial pathological process of spinal cord injury ...ER stress and ICA in SCI are unclear ...ER stress was investigated in vitro and in ...
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Original Article Berberine improves motor function recovery by inhibiting endoplasmic reticulum stress-induced neuronal apoptosis via AMPK activation in rats with spinal cord injury
... direct damage at the injured location and include disturbances in ionic homeostasis, local edema, focal hemor- rhage, excitotoxicity, oxidative stress, inflam- mation, and ...the damage initiated by ...
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Neuronal Alterations and Antioxidant Status of Lipopolysaccharide Induced Neuronal damage in Mice: Efficacy of Three Medicinal Plants
... types as seen in human patients, it is first necessary to evaluate whether neurodegeneration occurs in animal models. It is sometimes important to establish probably at which age and in which part of the brain ...
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Ethyl acetate extract of Wedelia chinensis inhibits tert butyl hydroperoxide induced damage in PC12 cells and D galactose induced neuronal cell loss in mice
... progressive neuronal loss that leads to functional ...delay neuronal damage is reducing brain oxidative ...oxidative stress in brain ...oxidative stress might induce cell apoptosis we ...
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The Effect of PTZ - Induced Seizures on Neuronal Damage in Amygdala of Rats
... The relationship between seizures and subsequent pathological conditions in central nervous system has been widely investigated. Animal and human studies have provided clear evidences that seizures can cause brain ...
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Disruption of the nuclear p53-GAPDH complex protects against ischemia-induced neuronal damage
... onal damage following ischemia or excitotoxicity came from studies showing that p53 levels are increased in re- sponse to these insults ...(1) neuronal death in the hippocampal CA1 region was much more ...
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Mitochondrial neuronal uncoupling proteins: a target for potential disease modification in Parkinson's disease
... [44]. Neuronal UCP expression appears to be responsive to oxidative stress in various in vitro and in vivo experimental models of PD ...oxidative stress, demon- strating a potential local feedback ...
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Interplay of Oxidative Stress and Autophagy in PAMAM Dendrimers-Induced Neuronal Cell Death
... nanoparticles induced ROS generation in macrophages and simultaneously induced autophagy and apoptosis, indicating that autophagy might be a cellular defense mechanism against ...dendrimers-induced ...
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Analysis of Momordica charantia Polysaccharide Components and Their Effects on KA Induced Oxidative Stress and Neuronal Loss in the Hippocampus of Epileptic Rats
... oxidative stress in the ...radical damage have been widely studied and are well ...KA-induced neuronal damage by determining the levels of MDA and the activities of SOD and CAT in the ...
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Phospholipase A2 is involved in galactosylsphingosine induced astrocyte toxicity, neuronal damage and demyelination
... AP1 and NFκB [46]. The metabolism of arachidonic acid also gives rise to ROS, which may induce oxidative stress [47]. The arachidonic acid (and/or lysophosphatidylcholine, LPC) sig- nalling pathway(s) likely ...
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Protective Effect of Polyherbal Formulation on Experimentally Induced Ulcer in Rats
... PHF showed significant ulcer protective effects as observed from significant decrease in acute ulcers induced by pyloric ligation and indomethacin. Ulcers due to pyloric ligation are due to increased accumulation ...
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Nitrate and nitrite in drinking water affect antioxidant enzymes in erythrocytes of rats
... The present study evaluated the effect of short term intake of nitrite and nitrate drinking water on the antioxidant system and membrane damage of rat erythrocytes. Wistar rats, were randomly divided into three ...
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The effect of intestinal inflammation and enteric nervous system deregulation in the pathogenesis of Parkinsonian syndrome
... Montojo and others have shown that the environmental toxin rotenone acts locally on the enteric neurons and triggers release of α-synuclein via exosomes (Pan-Montojo et al., 2012). Indeed, many animal studies of ...
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Bouman, Lena (2010): A role of parkin in stress response pathways. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... cellular stress, as the patients suffer from early onset ...oxidative stress, resulting in a loss of function (LaVoie et ...moderate stress conditions, whereas under severe stress, which ...
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Ameliorating effects of aged garlic extracts against Aβ induced neurotoxicity and cognitive impairment
... Aged garlic which is recently available on the market in Korea is one of garlic products expected to have strong antioxidant capacity. It has a soft fruity taste with a non- irritating odor. Aged garlic is produced by ...
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Monomeric amyloid-ß reduced amyloid-ß oligomer-induced synapse damage in neuronal cultures
... synapse damage in AD include the length of the Aβ fragment, oligomer size and the conformation of ...synapse damage even in the presence of high concentrations of Aβ ...
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