Stroke-prone spontaneously hypertensive rats (SHRsp)
Protective Effects of Nobiletin on Hypertension and Cerebral Thrombosis in Stroke Prone Spontaneously Hypertensive Rats (SHRSP)
... Male stroke prone spontaneously hypertensive rats (SHRSP), 6 weeks old, were obtained from Japan SLC (Hamamatsu, ...The rats were euthanized with an overdose of sodium ...
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Differential effects of dietary canola and soybean oil intake on oxidative stress in stroke-prone spontaneously hypertensive rats
... WKY rats, canola oil ingestion increased lipid peroxide levels in the hepatic cytosol [26], while an earlier study showed no change in lipid peroxide levels in the hepatic cytosol of SHR ...
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Arginine vasopressin altered the expression of monocarboxylate transporters in cultured astrocytes isolated from stroke-prone spontaneously hypertensive rats and congenic SHRpch1_18 rats
... SHRpch1_18 rats than in WKY/Izm ...SHRSP/Izm rats, hydroxyl radicals are produced under H/R conditions ...WKY/Izm rats, the generation of hydroxyl radicals in hippocampal neuronal cells peaked 20 min ...
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Regulation of blood pressure and glucose metabolism induced by L- tryptophan in stroke-prone spontaneously hypertensive rats
... At the end of the experimental period, there were no differences in the final body weight, body weight gain, or daily food intake (Additional file 2, Table S2: Effect of diet on food intake, weight gain, and final body ...
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Effects of Angiotensin II Type 1 receptor blocker and adiponectin on adipocyte dysfunction in stroke-prone spontaneously hypertensive rats
... extended their life-span, and decreased the incidence of stroke (unpublished data). These results suggest that adipocyte dysfunction is related to hypertension in SHRSP. Moreover, A-ZIP/F-1 mice, an animal model ...
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The effect of short-term canola oil ingestion on oxidative stress in the vasculature of stroke-prone spontaneously hypertensive rats
... SHRSP rats (Deakin University, Australia) aged 4 weeks were randomly assigned to either group 1 (n = 20) or group 2 (n = ...the rats were randomly assigned to a control or treatment group and acclimatized ...
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Fermented rice bran supplementation mitigates metabolic syndrome in stroke prone spontaneously hypertensive rats
... administration Rats that had systolic BP of approximately 175 mm/Hg were used to investigate whether or not ingesting FRB at a single oral dose of 2 g/kg body weight produces an antihyperten- sive effect ...
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Association and cosegregation of stroke with impaired endothelium dependent vasorelaxation in stroke prone, spontaneously hypertensive rats
... of stroke in both SHRSP and humans, and there is epidemiological data indicating that ethnic groups with particularly low potassium and high sodium intake show an excessively high incidence of cerebrovascular ...
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Low cardiovascular risks in the middle aged males and females excreting greater 24-hour urinary taurine and magnesium in 41 WHO-CARDIAC study populations in the world
... and stroke as previously reported ...from stroke-prone spontaneously hypertensive rats (SHRSP) were significantly higher than in normotensive Wister- Kyoto rats (WKY), and ...
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Original Article Comparison study on antihypertensive drugs for treatment of pre-hypertension in rats
... in stroke-prone spontaneously hypertensive rats ...Wistar-Kyoto rats were used as a control. Rats were followed up until ...method. Stroke was determined with the ...
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Cardiopulmonary responses of Wistar Kyoto (WKY), spontaneously hypertensive rats (SHR) and stroke prone SHR (SHRSP) to particulate matter (PM) exposure
... Specific metal-metal interactions may be causing biological changes within the organs and cells. A significantly higher level of lead (Fig. 17B) as well as zinc (Fig. 15D) was measured in the livers of PM exposed ...
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Stimulation of Adipose Tissue Lipoprotein Lipase Activity Improves Glucose Metabolism and Increases High Density Lipoprotein Cholesterol in the Spontaneously Hypertensive Stroke-Prone Rat
... Insulin resistance syndrome (IRS), high blood pressure, elevated blood glucose and triacylglycerol-rich lipoproteins (TG-RL), as well as low levels of high-density lipoprotein (HDL-C) are disorders that combine to define ...
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Progesterone reduces erectile dysfunction in sleep-deprived spontaneously hypertensive rats
... Concerning hormone alterations, the present results are in line with our previous studies reporting a marked reduction in testosterone in PSD rats whereas progester- one levels were increased significantly. ...
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Association of chronic diabetes and hypertension in sural nerve morphometry: an experimental study
... in hypertensive rats are very likely to be explained by the morphological changes in endoneural microvessels associated with hyper- tension, as described before ...STZ-diabetic rats, but includes ...
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Effect of heme arginate administration on blood pressure in spontaneously hypertensive rats
... of spontaneously hypertensive rats (SHR) as compared with those of normotensive, Wistar-Kyoto (WKY), control rats during the period of rapid elevation of blood ...
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Moderate Effect of Flavonoids on Vascular and Renal Function In Spontaneously Hypertensive Rats
... the hypertensive load on vascular tissues, increased monocyte and platelet adhesion with the release of growth factors would contribute to the thickening of the vascular ...
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Prestroke Proteomic Changes in Cerebral Microvessels in Stroke-Prone, Transgenic[hCETP]-Hyperlipidemic, Dahl Salt-Sensitive Hypertensive Rats
... rat stroke model of ischemic- hemorrhagic stroke induced by early life sodium exposure in an inbred polygenic- hypertensive, transgenic-hyperlipidemic Dahl salt-sensitive (Dahl-S) rat, Tg25sp model ...
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Hypertension effects on p73 expression in the rat circumventricular organs and cerebrospinal fluid
... The SHRs present an elevation of blood pressure from 10 weeks of age and a progressive increase of ventricular size from 4 to 56 weeks of age (Ritter and Dinh, 1986). Martinez-Peña y Valenzuela et al. [6] described that ...
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Impairment of selectin mediated leukocyte adhesion to venular endothelium in spontaneously hypertensive rats
... between spontaneously hypertensive rats and Wistar Kyoto ...Kyoto rats, 10 microM histamine as well as 500 microM tertbutyl hydroperoxide promoted a significant reduction of venular leukocyte ...
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Parecoxib is neuroprotective in spontaneously hypertensive rats after transient middle cerebral artery occlusion: a divided treatment response?
... Anesthesia induction was accomplished within two min- utes in a chamber filled with 5% isoflurane (Baxter Isoflu- rane, Baxter Medical) in a 35/65% oxygen (O 2 ) and nitrous oxide (N 2 O) atmosphere. Following weighing ...
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