Stromal cell-derived factor 1
Fibroblast like synoviocytes support B cell pseudoemperipolesis via a stromal cell–derived factor 1– and CD106 (VCAM 1)–dependent mechanism
... chemokine stromal cell–derived factor-1 (SDF-1), and that pertussis toxin or antibod- ies to the SDF-1 receptor (CXCR4) could inhibit B-cell ...β 1 integrin, ...
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Original Article Platelet-derived growth factor and stromal cell-derived factor-1 promote the skin wound repairing effect of bone mesenchymal stem cells: a key role of matrix metalloproteinase 1 and collagens
... growth factor (PDGF) and stromal cell- derived factor-1 (SDF-1) on BMSCs was also preliminarily ...growth factor (bFGF), interleukin 1β (IL-1β), PDGF, SDF-1, ...
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Study on the Relationship between Stromal Cell Derived Factor 1 (SDF 1) and Gastric Cancer
... cancer. Stromal cell-derived factor-1 (SDF-1, also known as CXCL12) is a member of the CXC chemokine family that binds to the receptor CXCR4 and participates in the body’s ...
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Expression of stromal cell derived factor 1 and CXCR7 ligand receptor system in pancreatic adenocarcinoma
... cancer. Stromal cell-derived factor 1 (SDF-1) is a chemotactic factor for T cells, monocytes, hematopoietic progenitor cells, dendritic cells, endothelial cells, and tumor ...
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Ultrasound-targeted stromal cell-derived factor-1-loaded microbubble destruction promotes mesenchymal stem cell homing to kidneys in diabetic nephropathy rats
... stem cell (MSC) therapy has been considered a promising strategy to cure diabetic nephropathy ...therapy. Stromal cell-derived factor-1 (SDF-1) plays a vital role in MSC ...
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p21Cip1 modulates arterial wound repair through the stromal cell–derived factor 1/CXCR4 axis in mice
... vascular cell growth and death critically regulates the determina- tion of both the composition of the healed arterial wall and lumi- nal ...the cell cycle and proliferate ...chemokine stromal ...
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Modulation of stromal cell-derived factor 1 alpha (SDF-1α) and its receptor CXCR4 in Porphyromonas gingivalis-induced periodontal inflammation
... as stromal cell- derived factor 1 alpha (SDF-1α), is constitutively expressed by human gingival fibroblasts (HGFs) and by human peri- odontal ligament (PDL) fibroblasts ...non-redundant ...
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Chemotaxis of primitive hematopoietic cells in response to stromal cell–derived factor 1
... Blocking of transmigration of CAFCs to an SDF-1 gradient with mAb CXCR4. To clarify that SDF-1 attracts primi- tive progenitor/stem cells via CXCR4, SDF-1 (100 ng/mL) was added in the lower chamber ...
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Pro inflammatory properties of stromal cell derived factor 1 (CXCL12) in collagen induced arthritis
... pooled. Cell suspensions were cultured for 6 days on a quartz substrate coated with a calcium phosphate film in the presence of macrophage colony-stimulating factor (M-CSF, 20 ng/ml) and receptor activator ...
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Directed migration of human neural progenitor cells to interleukin 1β is promoted by chemokines stromal cell derived factor 1 and monocyte chemotactic factor 1 in mouse brains
... In order to achieve endogenous repair, the first step for NPCs is to migrate to regions of brain injury before differ- entiating into cells with the correct phenotype and then in- tegrate appropriately into neuronal ...
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CXC chemokine ligand 12/Stromal cell-derived factor-1 regulates cell adhesion in human colon cancer cells by induction of intercellular adhesion molecule-1
... The cell surface ICAM-1 protein expression levels were determined by cell surface ELISA analyses (B, ...DLD-1 cell lysate after SDF-1 stimulation for the times indicated was ...
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TNF inhibits production of stromal cell derived factor 1 by bone stromal cells and increases osteoclast precursor mobilization from bone marrow to peripheral blood
... To determine whether the reduction in bone marrow expres- sion of SDF-1 induced by TNF leads to OCP mobilization, we treated wild-type mice with TNF using a subcutaneous injec- tion protocol shown previously to ...
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Stromal cell-derived factor 1 polymorphism in patients infected with HIV and implications for AIDS progression in Tunisia
... Allelic and genotypic frequencies were evaluated by tools used for population genetic analyses, ie, SPSS version 16.0 (SPSS Inc., Chicago, IL), as well as by calculating OR and P values. In fact, we had to do an ...
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SDF-1 Improves Renal Fibrosis in Type 2 Diabetes Mellitus Involving TGF-beta-mediated ECM via PI3K/AKT Signaling
... of stromal cell-derived factor-1 in the progression of renal injury in type 2 diabetic ...of stromal cell-derived factor-1, CXC chemokine receptor 4 ...
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Preconditioning of bone marrow-derived mesenchymal stromal cells by tetramethylpyrazine enhances cell migration and improves functional recovery after focal cerebral ischemia in rats
... that stromal cell-derived factor-1 (SDF-1) contributes largely to recruitment of stem cells to ischemic tissue by combining with its re- ceptor CXC chemokine receptor 4 (CXCR4) ...
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Children are not little adults: just ask their hematopoietic stem cells
... and cell cycling ...the cell cycle at much higher rates than that of adult HSCs; however, this increased frequency of cycling abruptly ceases 4 weeks after birth (see the related article beginning on page ...
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Stromal derived factor 1 (SDF 1) expression during early chick development
... of stromal cell-derived factor-1 and its receptor are also particu- larly noticeable in the developing cardiac, vascular and craniofa- cial system during organogenesis (McGrath et ...
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<p>CXCL13 Is A Biomarker Of Anti-Leucine-Rich Glioma-Inactivated Protein 1 Encephalitis Patients</p>
... other cell types into the ...B cell markers, such as CXCL13(B-lymphocyte chemoattractant, BLC) and BAFF (B cell activating factor), have been most extensively inves- tigated and are found to ...
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Remodeling the Microenvironment before Occurrence and Metastasis of Cancer
... growth factor-β; hStCs: Hepatic stellate cells; FN: Fibronectin; LOXL2: Lysy1 oxidase-like2; EMT: Epithelial mesenchymal transition; ER: Endoplasmic reticulum; YAP: Yes-associated protein; TAZ: Transcriptional ...
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Myoblast-conditioned media improve regeneration and revascularization of ischemic muscles in diabetic mice
... Results: Expression of HO-1 was lower in muscle satellite cells isolated from muscles of diabetic db/db mice when compared to their wild-type counterparts, what was accompanied by increased levels of Myf5 or ...
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