Stromal-derived factor-1
Occurrence of Stromal Derived Factor-1 Polymorphism In Kenyan Population
... stimulating factor) binds on to the CXCR4 coreceptor, it down regulates the invasion of the CD4+ T-cells by the HIV (Yuan et ...- 1 o c c u r s i n i t s w i l d f o r m w i t h guanine/guanine (G/G) in its ...
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Stromal derived factor 1 (SDF 1) expression during early chick development
... respectively. Stromal-derived factor-1 (SDF-1/CXCL12), a ligand of the chemokine receptor, CXCR4, is involved in providing cells with directional cues as well as in controlling their ...
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Nef Proteins from Diverse Groups of Primate Lentiviruses Downmodulate CXCR4 To Inhibit Migration to the Chemokine Stromal Derived Factor 1
... type 1 (HIV-1) and the majority of HIV-2 Nef proteins tested did not have such strong ...chemokine stromal derived factor 1 ...
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Expression of stromal cell derived factor 1 and CXCR7 ligand receptor system in pancreatic adenocarcinoma
... tumor cells, including breast cancer cells, pancreatic cancer cells, and hepatocellular carcinoma cells [8,9]. Recently, a novel receptor for SDF-1, called CXCR7, has been identified and it has been hypothesized ...
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Modulation of stromal cell-derived factor 1 alpha (SDF-1α) and its receptor CXCR4 in Porphyromonas gingivalis-induced periodontal inflammation
... as stromal cell- derived factor 1 alpha (SDF-1α), is constitutively expressed by human gingival fibroblasts (HGFs) and by human peri- odontal ligament (PDL) fibroblasts ...non-redundant ...
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Migration towards SDF-1 selects angiogenin-expressing bone marrow monocytes endowed with cardiac reparative activity in patients with previous myocardial infarction
... Following these considerations, immunomagnetically and antigenically sorted CD133 + or CD34 + PCs have been proposed for cardiovascular cell therapy [18-20]. Another attractive option is to select cells on the basis of ...
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Pro inflammatory properties of stromal cell derived factor 1 (CXCL12) in collagen induced arthritis
... We also considered the possibility that CXCL12 favours CIA development by somehow affecting systemic cytokine produc- tion. In wild-type DBA/1 mice immunized to develop CIA, we found production of circulating ...
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Children are not little adults: just ask their hematopoietic stem cells
... as stromal cell–derived factor 1 [SDF-1]), a chemokine previously implicated in stem cell trafficking to the marrow cavity and shown to be expressed by cells within the hematopoietic ...
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<p>CXCL13 Is A Biomarker Of Anti-Leucine-Rich Glioma-Inactivated Protein 1 Encephalitis Patients</p>
... activating factor), have been most extensively inves- tigated and are found to be elevated in autoantibody-asso- ciated CNS disorders; while helper T cell2 (Th2) and Th17 cytokines, such as interleukin (IL)4, ...
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Paclitaxel-activated astrocytes produce mechanical allodynia in mice by releasing tumor necrosis factor-α and stromal-derived cell factor 1
... Paclitaxel has been suggested to elicit pain by engaging microglia and neurons via TLR4 [16, 25]. However, we have showed that the astrocytic inhibitor L-α-AA signifi- cantly attenuated P-APS and found that paclitaxel- ...
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Modulation of Feline Immunodeficiency Virus Infection by Stromal Cell-Derived Factor
... Intriguingly, CrFK cells were recognized by the cross-spe- cies-reactive anti-CXCR4 antibodies whereas Mya-1 cells were not, despite CXCR4 mRNA being abundant in both cell lines (56). Such anomalies have been ...
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Phenotypic correction of Fanconi anemia cells in the murine bone marrow after carrier cell mediated delivery of lentiviral vector
... of stromal derived factor-1α (SDF-1α) and traffic FANCC expressing LV to Fancc –/– murine hematopoietic stem and progenitor cell (HSPC) target cells, with subsequent trans- duction (TD) and expansion ...
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Ultrasound-targeted stromal cell-derived factor-1-loaded microbubble destruction promotes mesenchymal stem cell homing to kidneys in diabetic nephropathy rats
... When introduced into circulation, the MBs remained mostly intact, and no obvious bioeffect was induced under this condi- tion. In addition, they were limited to circulating only within blood vessels and reflected much ...
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SDF-1 Improves Renal Fibrosis in Type 2 Diabetes Mellitus Involving TGF-beta-mediated ECM via PI3K/AKT Signaling
... of stromal cell-derived factor-1 in the progression of renal injury in type 2 diabetic ...of stromal cell-derived factor-1, CXC chemokine receptor 4 and F4/80 were ...
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<p>The anti-apoptotic effect on cancer-associated fibroblasts of B7-H3 molecule enhancing the cell invasion and metastasis in renal cancer</p>
... in vitro demonstrated that B7-H3 + CAFs plays a signi fi cant role in tumor growth and metastatic progression. The orthotopic xenograft tumor model of nude mice was also established to further con fi rm the effect of B7-H3 ...
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Myoblast-conditioned media improve regeneration and revascularization of ischemic muscles in diabetic mice
... Results: Expression of HO-1 was lower in muscle satellite cells isolated from muscles of diabetic db/db mice when compared to their wild-type counterparts, what was accompanied by increased levels of Myf5 or ...
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Leptomeningeal Carcinomatosis as a Presentation of Relapse in Adenocarcinoma of Colon: A Case Report and Review Ramchandani Santosh 1, Ashish Manne1 , Ankit Madan 1and Ravi Kumar Paluri 1*
... growth factor (VEGF) and stromal cell derived factor (SDF)-1 levels in patients with neoplastic meningitis (NM) due to breast cancer, lung cancer and ...
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The involving progress of MSCs based therapy in atherosclerosis
... them, stromal cell-derived factor 1 (SDF-1), recruiting BMSCs from their origin such as bone marrow, and their receptor CXC chemokine recep- tor 4 (CXCR4), for BMSCs being localized to ...
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Chemotaxis of primitive hematopoietic cells in response to stromal cell–derived factor 1
... Blocking of transmigration of CAFCs to an SDF-1 gradient with mAb CXCR4. To clarify that SDF-1 attracts primi- tive progenitor/stem cells via CXCR4, SDF-1 (100 ng/mL) was added in the lower chamber ...
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Study on the Relationship between Stromal Cell Derived Factor 1 (SDF 1) and Gastric Cancer
... The structure and interaction mechanism of SDF-1 and its receptor CXCR4 are the basis for exerting its pathological and physiological functions. Studies [12] have found that overexpression of SDF-1 induces ...
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