Structural Motifs
Structural Motifs of Novel Metallothionein Proteins
... Zinc is critical to the continued health of an organism and is required for the proper functioning of a number of enzymes and transcription factors. With 5-20% of all cellular Zn associated with MT, structural ...
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Unusual Topological Arrangement of Structural Motifs in the Baboon Reovirus Fusion-Associated Small Transmembrane Protein
... p10 structural motifs, a predicted ectodomain cystine noose and the palmitoylated dicysteine motif in the endodomain, both of which are required for p10 fusion activity (46, ...tural motifs and (by ...
11
Intra- and Intersubtype Alternative Pak2-Activating Structural Motifs of Human Immunodeficiency Virus Type 1 Nef
... Pak2-activating motifs that differ from those found in subtype B and E ...Pak2-activating structural motifs that singly affect one Nef activity revealed a functional plasticity that has implications ...
6
Isomerisation of nido [C2B10H12]2 dianions : unprecedented rearrangements and new structural motifs in carborane cluster chemistry
... characterised. For ortho- and meta-carborane the experimental reduction produces 7,9 in both cases and computed pathways for both processes are also de fi ned; with ortho-carborane rearrangement occurs via 7,8, whereas ...
12
cis-active structural motifs involved in specific encapsidation of Moloney murine leukemia virus RNA.
... During expression of retroviral genomes, newly transcribed viral RNAs assume at least two functions. In additional to acting as mRNAs, unspliced viral transcripts are encapsidated into assembling particles as the viral ...
8
Conserved structural motifs located in distal loops of aphthovirus internal ribosome entry site domain 3 are required for internal initiation of translation.
... A comparison of picornavirus internal ribosome entry site (IRES) secondary structures revealed the exis- tence of conserved motifs located on loops. We have carried out a mutational analysis to test their ...
5
Protein function prediction using family-specific structural motifs
... or structural similarity may have the same function because their active sites could have remained conserved throughout the evolution unlike their remaining ...through motifs (local similarity), the main ...
113
Identification of Common Structural Motifs from Proteases, Kinases, and Phosphatases Using a New Structure Comparison Method
... in distance-based, and a genetic algorithm in secondary structure- based [6] comparisons. Dynamic programming algorithms have been used in both distance- [7-9] and secondary structure-based [8,10] comparisons. There are ...
5
First-Principles Exploration of the Structural Motifs of Chalcogenides and Their Relationship to Electronic and Photovoltaic Properties
... The predictive ability of the tolerance factor can be further enhanced by taking elec- tronegativity into account in a manner similar to Pearson,[108] and specifying a new gen- eralized t factor, t 0 = t∆χ(X-A)/∆χ(O-A), ...
150
Optical Fingerprints of Si Honeycomb Chains and Atomic Gold Wires on the Si(111) (5x2) Au Surface
... Experiment shows that the real surface is of mixed microdomain character [9,16,37], but we start by consid- ering the optical signal of a simple single domain. The RAS response for the original AN model ( C ), the ...
5
Characterization of amphioxus nebulin and its similarity to human nebulin
... Identification of a large molecule in muscle is important but difficult to approach by protein chemistry. In this study we isolated nebulin cDNA from the striated muscle of amphioxus, and characterized the C-terminal ...
5
Random generation of RNA secondary structures according to native distributions
... known structural motifs that may occur in unknotted RNA secondary ...any structural feature is modeled by one or more specific grammar rules with corresponding probabilities observed from real-life ...
46
Genetic Divergence of Rotavirus Nonstructural Protein 4 Results in Distinct Serogroup-Specific Viroporin Activity and Intracellular Punctate Structure Morphologies
... RVB and RVC NSP4s also have motifs characteristic of viro- porins. We used helical wheel diagrams to look at the orientation of the basic residues within the RVB and RVC putative viroporin domains. In RVB NSP4, ...
14
Theological ambiguities: a challenge to a constructive ecotheology in Africa
... Sindima shows that, the contemporary African society, basing on the above view as the key challenge. This is where he points out, as a result of Western influence, which has changed the African cosmology that informs ...
7
Time Series Motifs in Practice.
... The first approach attempts to label a time series by finding the class signatures, the subsequences that are likely to exist in a time series if it belongs to a certain class. Motif instances are found by a new motif ...
125
Pure early zygotic genes in the Asian malaria mosquito Anopheles stephensi
... VBRGGTA motifs, two similar regulatory motifs that activate early zygotic transcription were found to be enriched in the upstream sequences of the Drosophila and Aedes pEZGs [14], ...the structural ...
11
Ethnomathematics as Indonesia Batik Artwork in Mathematics Learning Two-dimensional Figure Materials
... The ability to think critically must be trained from an early age. As students progress into junior and senior high school, critical thinking skills, decision-making skills, and information gathering skills need to be ...
8
Impact of cancer mutational signatures on transcription factor motifs in the human genome
... In this study, we investigated the theoretical impact of cancer mutational signatures on regulatory elements of the non-coding genome and provided an outline of a Bayesian framework for motif alteration analysis using ...
14
Drug-Target Interaction Networks Prediction Using Short-linear Motifs
... We propose a new feature-based method to predict drug-target interaction which firstly introduces short-linear motifs (SLiMs) as protein features into this field. Dif- ferent from n-gram, SLiMs have biological ...
62
Woodard_unc_0153D_16573.pdf
... One way to design for new capsid variants is to build from a known serotype by adding mutations or motifs. This is the method used when adding the HS-binding motif to the various rAAV capsids. The addition of the ...
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