Superparamagnetic Iron-Oxide (Uspio)
Ultrasmall superparamagnetic iron oxide nanoparticles acutely promote thrombosis and cardiac oxidative stress and DNA damage in mice
... Ultrasmall superparamagnetic iron oxide nanoparticles (USPIO, < 50 nm) have an iron oxide core that is monomer or polymer-coated/stabilized. They possess highly reactive surface, ...
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Ultrasmall cationic superparamagnetic iron oxide nanoparticles as nontoxic and efficient MRI contrast agent and magnetic-targeting tool
... ultrasmall superparamagnetic iron oxide nanoparticles caused no effects on hepatic and renal enzymes dosage as well as on leukocyte ...ultrasmall superparamagnetic iron oxide ...
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RADIATION DOSE ENHANCEMENT EFFECTS OF SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES TO THE T24 BLADDER CANCER CELL LINES IRRADIATED WITH MEGAVOLTAGE PHOTON BEAM RADIOTHERAPY
... reported. Superparamagnetic iron oxide nanoparticles (SPION) could also potentially have therapeutic properties that can be exploited to enhance radiotherapy ...
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Studying the effect of particle size and coating type on the blood kinetics of superparamagnetic iron oxide nanoparticles
... Purpose: Magnetic resonance imaging (MRI), one of the most powerful imaging techniques available, usually requires the use of an on-demand designed contrast agent to fully exploit its potential. The blood kinetics of the ...
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Superparamagnetic iron oxide nanoparticles conjugated with epidermal growth factor (SPION–EGF) for targeting brain tumors
... Abstract: Superparamagnetic iron oxide nanoparticles (SPIONs) conjugated with recombinant human epidermal growth factor (SPION–EGF) were studied as a potential agent for magnetic resonance imaging ...
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Optimizing superparamagnetic iron oxide nanoparticles as drug carriers using an in vitro blood–brain barrier model
... of superparamagnetic iron oxide nanoparticle (SPION) samples, the BBB was first examined and confirmed by an immunofluorescent stain and evaluating the transendothelial electrical ...
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Quantification of the internalization patterns of superparamagnetic iron oxide nanoparticles with opposite charge
... [6,7,27,28], superparamagnetic iron oxide NPs (SPIONs) were selected as systems to investigate NP internalization patterns; firstly qualitatively via flow cyto- metry (Fluorescence-Activated Cell ...
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Superparamagnetic iron oxide nanoparticles: magnetic nanoplatforms as drug carriers
... of iron with transition metal ions such as copper, cobalt, nickel, and manganese, are known to exhibit super- paramagnetic properties and also fall into the category of ...
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Magnetic resonance sentinel lymph node imaging and magnetometer-guided intraoperative detection in prostate cancer using superparamagnetic iron oxide nanoparticles
... A total of 50 consecutive patients with intermediate- or high-risk PCa (prostate-specific antigen [PSA] 10 ng/mL and/or Gleason score 7) scheduled to undergo transrectal SPION injection before magnetometer-guided sLND ...
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Evaluation of uptake and transport of cationic and anionic ultrasmall iron oxide nanoparticles by human colon cells
... ultrasmall superparamagnetic iron oxide nanoparticles (USPIO NPs) (iron oxide core 9–10 nm) coated with either cationic polyvinylamine (aminoPVA) or anionic oleic acid with human HT-29 ...
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Targeting experimental orthotopic glioblastoma with chitosan-based superparamagnetic iron oxide nanoparticles (CS-DX-SPIONs)
... Results: CS-DX-SPIONs nanoparticles showed a uniform diameter of 55 nm under TEM and superparamagentic characteristics as determined by T 1 (spin-lattice relaxation time) and T 2 (spin- spin relaxation time) proton ...
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Influence of synthetic superparamagnetic iron oxide on dendritic cells
... Under transmission electron microscopy, γ -Fe 2 O 3 nanopar- ticles were measured at an average diameter around 8.7 nm, and were seen as nearly spherical shapes (Figure 1A). A vibrating sample magnetometer demonstrated ...
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One-Pot Facile Synthesis of New 1, 2, 4-Triazolidine Derivatives Using Sodium Borohydride and Fe3O4 Magnetic Nanoparticles (MNPs)
... Recently, superparamagnetic iron oxide nanoparticles (SPIONs) have been intensively investigated because of their super paramagnetic properties, excellent catalytic activity in organic synthesis, ...
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MRI of Breast Tumor Initiating Cells Using the Extra Domain-B of Fibronectin Targeting Nanoparticles
... targeting superparamagnetic iron oxide nanoparticles (SPIONs) could be used as a magnetic resonance imaging (MRI) contrast agent for BTIC imaging in vitro and in ...
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In vitro Study of SPIONs-C595 as Molecular Imaging Probe for Specific Breast Cancer (MCF-7) Cells Detection
... agents to specifically target cancer cells has previously been demonstrated for several cancers [2,6-10] . Shahbazi- Gahrouei et al. [6,7] investigated the detection of ovarian cancer (OVCAR3) cells using C595 monoclonal ...
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Magnetic nanoparticles: preparation, physical properties, and applications in biomedicine
... magnetic iron oxide, directs nucleation, controls growth, and sterically stabilizes the resulting 5-nm superparamagnetic iron ...prepare superparamagnetic polymeric nanoparticles by ...
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<p>Strategies to enhance efficacy of SPION-labeled stem cell homing by magnetic attraction: a systemic review with meta-analysis</p>
... Abstract: Stem cells possess a promising potential in the clinical fi eld. The application and effective delivery of stem cells to the desired target organ or site of injury plays an important role. This review describes ...
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Low toxic maghemite nanoparticles for theranostic applications
... toxic superparamagnetic iron oxide nanoparticles (SPIONs) for theranostic applications in oncology having spherical shape and maghemite structure were produced using the fast microwave synthesis ...
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Remote magnetic targeting of iron oxide nanoparticles for cardiovascular diagnosis and therapeutic drug delivery: where are we now?
... Abstract: Magnetic resonance imaging (MRI) allows for an accurate assessment of both functional and structural cardiac parameters, and thereby appropriate diagnosis and validation of cardiovascu- lar diseases. The ...
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Magnetic particle imaging: current developments and future directions
... of superparamagnetic iron oxide nanoparticles ...SPIONs’ superparamagnetic characteristics, the fact that they are magnetically saturable, and the harmonic composition of the SPIONs’ response ...
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