Synaptonemal complex protein 3
Synaptonemal complex protein 3 is associated with lymphangiogenesis in non small cell lung cancer patients with lymph node metastasis
... Synaptonemal complex protein 3 (SCP3) is a DNA- binding protein and a structural component of the syn- aptonemal complex, which mediates the synapsis or homologous pairing of ...
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Synaptonemal Complex Protein 3 Transcript Analysis in Breast Cancer
... gene; Synaptonemal Complex Protein 3 was de- tected in breast cancer tumors and five breast cancer cell lines, where it should not be normally ...
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Drosophila Oocytes as a Model for Understanding Meiosis: An Educational Primer to Accompany “Corolla Is a Novel Protein That Contributes to the Architecture of the Synaptonemal Complex of Drosophila”
... Localizing proteins via immunofluorescence requires at least two sets of antibodies. Primary antibodies are raised in different species (mouse, rabbit, rat, guinea pig, and chicken are the most common) and are selected ...
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Phylogenies of Central Element Proteins Reveal the Dynamic Evolutionary History of the Mammalian Synaptonemal Complex: Ancient and Recent Components
... CR protein described in Drosophila melanogaster; and the Caenorhabdi- tis elegans CR proteins SYP-2, SYP-3, and SYP-4 (RefSeq: NP_504462, NP_492345, and NP_491960) as seeds to query public sequence ...
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Corona is required for higher-order assembly of transverse filaments into full-length synaptonemal complex in Drosophila Oocytes
... The synaptonemal complex (SC) is an intricate structure that forms between homologous chromosomes early during the meiotic prophase, where it mediates homolog pairing interactions and promotes the formation ...
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Synaptonemal Complex Components Are Required for Meiotic Checkpoint Function in Caenorhabditis elegans
... relevant protein–protein interactions might not be recapitulated by yeast two-hybrid assays, these nega- tive data suggest that SYP-4 could uniquely interact with SYP-3 during ...
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In Vivo Analysis of Synaptonemal Complex Formation During Yeast Meiosis
... fluorescent protein (Figure ...By 3 hr many nuclei contained punctate fluorescent foci that we interpret to be due to the initiation of synapsis and the initial stages of SC formation at ...fluorescent ...
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Surface-spreading technique of meiotic cells and immunodetection of synaptonemal complex proteins in teleostean fishes
... During meiosis, specific events are required to promote genetic diversity and ensure the segregation of homolo- gous chromosomes. These events, including synapsis and meiotic recombination between homologous chro- ...
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Corolla Is a Novel Protein That Contributes to the Architecture of the Synaptonemal Complex of Drosophila
... Since SIM analysis virtually always identified Corolla as a single track running between the lateral sides of the SC— a pattern very similar to Cona—we wanted to determine whether Corolla and Cona physically interact. To ...
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The Puf RNA binding proteins FBF 1 and FBF 2 inhibit the expression of synaptonemal complex proteins in germline stem cells
... A crucial step in the development of the germline is the transition from an undifferentiated germ cell that divides by mitosis to a differentiating germ cell that is ready to begin meiosis. In animals, this transition ...
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Synaptonemal Complex Central Region Proteins Promote Localization of Pro-crossover Factors to Recombination Events During Caenorhabditis elegans Meiosis
... MutSg complex) and COSA-1 (a cyclin-related protein specific to metazoan meiosis) form multiple DSB-dependent foci in early pachytene prior to reducing down in number in late pachytene, marking the six CO ...
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A model for 3 methyladenine recognition by 3 methyladenine DNA glycosylase I (TAG) from Staphylococcus aureus
... binds 3-MeA but not adenine and binds protonated 3-MeA (pH ...neutral 3-MeA (pH ...of 3-MeA ...protonated 3-MeA ...DNA, 3-methyldeoxyadenosine can adopt a tautomer that has the ...
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Impact of mesenchymal stem cells’ secretome on glioblastoma pathophysiology
... with Protein Pilot software was used to assess the qual- ity of the identifications and positive identifications were considered when identified proteins and peptides reached a 5% local FDR [55, ...per ...
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Characterization of a Critical Interaction between the Coronavirus Nucleocapsid Protein and Nonstructural Protein 3 of the Viral Replicase-Transcriptase Complex
... replicase-transcriptase complex is assembled from 16 nsps that become autoproteolytically processed from two large polyproteins, which are translated from gRNA via a ribo- somal frameshift mechanism (1, ...N ...
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Proteins.ppt
... 3) In ER, protected peptide chain is able to make complex protein structures to be used in cell membrane/outside. cell/lysosomes.[r] ...
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LKB1, A New Biomarker in Breast Cancer
... Figure 1. Estrogen signaling pathways. (A) Estrogen binds to its receptor ER α in the cytoplasm leading to its dimerization and its translocation into the nucleus to act through a genomic me- chanism, where it binds ...
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Localization of Single- and Low-Copy Sequences on Tomato Synaptonemal Complex Spreads Using Fluorescence in Situ Hybridization (FISH)
... Fluorescence in situ hybridization (FISH) is a powerful means by which single- and low-copy DNA sequences can be localized on chromosomes. Compared to the mitotic metaphase chromosomes that are normally used in FISH, ...
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Hyperactivity of factor IX Padua (R338L) depends on factor VIIIa cofactor activity
... It is concerning, however, that higher FIX activity levels are being targeted and larger subject cohorts are being recruited without a clear understanding of the biochemical mechanism of FIX-R338L hyperactiv- ity. The ...
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GENETIC CONTROL OF SYNAPTONEMAL COMPLEXES IN DROSOPHILA MELANOGASTER
... Electron microscopists studying a (wide range of eucaryotic species (including fungi, flowerirlg plants, annelids, molluscs, crustaceans, spiders, insects, fish, amphibians, [r] ...
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Isolation of nuclear proteins from flax (Linum usitatissimum L ) seed coats for gene expression regulation studies
... a protein to bind a labeled DNA fragment in vitro, followed by electrophoretic separation of DNA-proteins complexes that migrate more slowly than free DNA ...nuclear protein extracts containing native ...
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