synaptonemal complex protein-3 (SYCP3)
Synaptonemal complex protein 3 is associated with lymphangiogenesis in non small cell lung cancer patients with lymph node metastasis
... Synaptonemal complex protein 3 (SCP3) is a DNA- binding protein and a structural component of the syn- aptonemal complex, which mediates the synapsis or homologous pairing of ...
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Synaptonemal Complex Protein 3 Transcript Analysis in Breast Cancer
... of SYCP3 transcripts in 47 breast tumors, 6 breast cancer cell lines (MCF7, SKBR3, T47D, BT474, MDA-MB-231 and MDA-MB 468), 5 normal breast and 2 testis tissues was studied by Real Time RT-PCR reac- ...of ...
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Effects of Guhanyangshengjing Tablet on Testosterone Synthesis and Expression of SYCP3 in the Testis of Aging Male Rats
... of synaptonemal complex protein 3 (SYCP3), a meiotic marker, in the testis tissue of aging male ...of SYCP3 in the GT-treated groups were all improved in a dose-dependent ...
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Corolla Is a Novel Protein That Contributes to the Architecture of the Synaptonemal Complex of Drosophila
... Since SIM analysis virtually always identified Corolla as a single track running between the lateral sides of the SC— a pattern very similar to Cona—we wanted to determine whether Corolla and Cona physically interact. To ...
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In Vivo Analysis of Synaptonemal Complex Formation During Yeast Meiosis
... (FU)/mg protein (Table teins extracted from the 120-kD band using MALDI- ...material protein was present in an ⵑ140-kD ...Spo22 protein. The gene that encodes this protein strings, punctate ...
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Phylogenies of Central Element Proteins Reveal the Dynamic Evolutionary History of the Mammalian Synaptonemal Complex: Ancient and Recent Components
... CR protein described in Drosophila melanogaster; and the Caenorhabdi- tis elegans CR proteins SYP-2, SYP-3, and SYP-4 (RefSeq: NP_504462, NP_492345, and NP_491960) as seeds to query public sequence ...
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Synaptonemal Complex Components Are Required for Meiotic Checkpoint Function in Caenorhabditis elegans
... In the absence of synapsis (for example, in syp-1 mutants), we can visualize pairing intermediates that typically precede and promote synapsis (MacQueen et al. 2002). Loss of PCH-2 further stabilizes pairing in syp-1 ...
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Drosophila Oocytes as a Model for Understanding Meiosis: An Educational Primer to Accompany “Corolla Is a Novel Protein That Contributes to the Architecture of the Synaptonemal Complex of Drosophila”
... bait protein is fused to the binding domain, and a prey protein is fused to the activating ...a protein interaction that happens in such a small number of ...
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Surface-spreading technique of meiotic cells and immunodetection of synaptonemal complex proteins in teleostean fishes
... During meiosis, specific events are required to promote genetic diversity and ensure the segregation of homolo- gous chromosomes. These events, including synapsis and meiotic recombination between homologous chro- ...
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Corona is required for higher-order assembly of transverse filaments into full-length synaptonemal complex in Drosophila Oocytes
... The synaptonemal complex (SC) is an intricate structure that forms between homologous chromosomes early during the meiotic prophase, where it mediates homolog pairing interactions and promotes the formation ...
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Approaching the Molecular Mechanism of Autophagy
... higher-order complex, and the delivery of this large complex to the vacuole requires the same set of proteins as starvation-induced autophagy and pexophagy ...membrane protein shown in vivo and in ...
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Role of a 300-Kilodalton Nuclear Complex in the Maturation of Trypanosoma brucei Initiator Methionyl-tRNA
... TbMT40 and TbMT53 are components of a nuclear 300-kDa complex. In a separate set of experiments, one aimed at puri- fying enzymes involved in the synthesis of the trypanosomatid cap 4 structure, we noted that ...
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Normal Synaptonemal Complex and Abnormal Recombination Nodules in Two Alleles of the Drosophila Meiotic Mutant mei-W68
... The meiotic phenotypes of two mutant alleles of the mei-W68 gene, 1 and L1, were studied by genetics and by serial-section electron microscopy. Despite no or reduced exchange, both mutant alleles have normal ...
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Organ culture of seminiferous tubules using a modified soft agar culture system
... of protein expression was determined using im- munocytochemistry (ICC) and immunohistochemistry (IHC) of colonies and frozen longitudinal section of STs, respectively (all antibodies were purchased from ...
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Characterization of a Critical Interaction between the Coronavirus Nucleocapsid Protein and Nonstructural Protein 3 of the Viral Replicase-Transcriptase Complex
... nucleocapsid protein (N) plays an essential structural role in virions through a network of interactions with positive-strand viral genomic RNA, the envelope membrane protein (M), and other N ...N ...
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Proteins.ppt
... 3) In ER, protected peptide chain is able to make complex protein structures to be used in cell membrane/outside. cell/lysosomes.[r] ...
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Hyperactivity of factor IX Padua (R338L) depends on factor VIIIa cofactor activity
... 3D, the appK D values of FIXa-R338L and FIXa-WT for FVIIIa in this assay were comparable (Table 1), which suggests that FVIIIa binds rFIXa-WT and rFIX-R338L similarly. These appK D values were used to determine the ...
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LKB1, A New Biomarker in Breast Cancer
... Figure 1. Estrogen signaling pathways. (A) Estrogen binds to its receptor ER α in the cytoplasm leading to its dimerization and its translocation into the nucleus to act through a genomic me- chanism, where it binds ...
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Localization of Single- and Low-Copy Sequences on Tomato Synaptonemal Complex Spreads Using Fluorescence in Situ Hybridization (FISH)
... Curtis, C. A., and A. J. Lukaszewski, 1991 Genetic linkage between lase-2 gene in barley (Hordeum vulgare). Genome 36: 517–523. C-bands and storage protein genes in chromosome 1B of tetra- Lichter, P., T. Cremer, ...
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Distribution of Crossing Over on Mouse Synaptonemal Complexes Using Immunofluorescent Localization of MLH1 Protein
... inhibitor cocktail to give a final total volume of 240 ml. A 20- on mammalian chromosomes recently became possible ml aliquot of cell suspension was placed on each of 12 slides, using fluorescent immunological detection ...
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