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synovial sarcoma

Metastatic biomarkers in synovial sarcoma

Metastatic biomarkers in synovial sarcoma

... receptor with an important role in homing of hematopoietic stem cells and lymphocyte trafficking that has been found to promote cell migration, invasion and angiogenesis [52, 81]. The CXCR4 pathway has been shown to be ...

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Original Article The interaction of SS18 and β-catenin promotes tumorigenesis of synovial sarcoma

Original Article The interaction of SS18 and β-catenin promotes tumorigenesis of synovial sarcoma

... Synovial sarcoma is a high-grade soft tissue malignancy and has a specific chromosomal translocation t(X; 18), which leads to the fusion of the SS18 gene to one of three SSX genes (SSX1, SSX2 or ...of ...

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Original Article Primary renal synovial sarcoma: two cases and review of the literature

Original Article Primary renal synovial sarcoma: two cases and review of the literature

... spindle-cell components, it contains three sub- types: monophasic, biphasic and poorly differ- entiated according to cell compositions [8]. Poorly-differentiated SS is composed of sheets of round or spindled cells ...

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Synovial sarcoma presenting with huge mediastinal mass: a case report and review of literature

Synovial sarcoma presenting with huge mediastinal mass: a case report and review of literature

... Morphologically, synovial sarcoma can show several growth patterns and is basically divided into monophasic and biphasic ...biphasic synovial sarcoma which consists of proliferation of bland ...

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Case Report Primary synovial sarcoma of the kidney-A case report and literature review

Case Report Primary synovial sarcoma of the kidney-A case report and literature review

... for synovial sarcoma is to demonstrate the fusion of the SYT (Synonyms: SS18-synovial sarcoma transloca- tion, chromosome 18) gene on chromosome 18 to either SSX1 (synovial ...

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Synovial sarcoma of  the maxillary sinus: an extremely rare case with excellent response to chemotherapy

Synovial sarcoma of the maxillary sinus: an extremely rare case with excellent response to chemotherapy

... of synovial sarcoma arising from the maxillary sinus, which resulted in a clinically complete response to ...chemotherapy. Synovial sarcoma is a rare soft tissue malignant tumor, most commonly ...

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Monophasic synovial sarcoma presenting as a primary ileal mass: a case report and review of the literature

Monophasic synovial sarcoma presenting as a primary ileal mass: a case report and review of the literature

... with synovial sarcoma into low-risk and high-risk groups depending on their age, tumor size and grade as follows: low-risk group (patient age < 25 years, tumor size < 5 cm, and no histologic evidence ...

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Ileo-ileal Intussusception Caused by Primary Monophasic Synovial Sarcoma (SS) of the Ileum

Ileo-ileal Intussusception Caused by Primary Monophasic Synovial Sarcoma (SS) of the Ileum

... for synovial sarcoma of the extremities, surgical excision with a wide margin is the only curative therapy and offers the best outcome; however, the application to intra abdominal cases is largely unstudied ...

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Original Article Diagnostic value of TLE1 for synovial sarcoma: immunohistochemical analyses of genetically confirmed synovial sarcomas and nonsynovial sarcomas

Original Article Diagnostic value of TLE1 for synovial sarcoma: immunohistochemical analyses of genetically confirmed synovial sarcomas and nonsynovial sarcomas

... of synovial sarcomas, Bcl-2 positivity in ...of synovial sarcomas ...42 synovial sarcomas, including 8 biopsy ...for synovial sarcomas on small biopsy samples. In our study, some ...

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A 63 year old woman presenting with a synovial sarcoma of the hand: a case report

A 63 year old woman presenting with a synovial sarcoma of the hand: a case report

... Introduction: Synovial sarcoma is a high-grade, soft-tissue sarcoma that most frequently is located in the vicinity of joints, tendons or bursae, although it can also be found in extra-articular ...

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Case Report Primary mediastinal synovial sarcoma: a case report and literature review

Case Report Primary mediastinal synovial sarcoma: a case report and literature review

... Abstract: Primary mediastinal synovial sarcoma (PMSS) is a rare malignant soft tissue tumor with a poor progno- sis. Because of its rarity, the misdiagnosis rate remains high. To raise awareness of this ...

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Intraneural Synovial Sarcoma of Femoral Nerve: A Case Study with Review of Literature

Intraneural Synovial Sarcoma of Femoral Nerve: A Case Study with Review of Literature

... [3] Synovial sarcoma is a class of mesenchymal tumors with no apparent relation to synovial tissue and their likely origin is from primitive undifferentiated mesenchymal cells present at any ...

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Poorly differentiated synovial sarcoma is associated with high expression of enhancer of zeste homologue 2 (EZH2)

Poorly differentiated synovial sarcoma is associated with high expression of enhancer of zeste homologue 2 (EZH2)

... preclinical synovial sarcoma model, presumably by disrupting the interactions within this complex ...of synovial sarcoma may open novel therapeutic ...

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Primary cardiac synovial sarcoma that was continuous with the mitral valve caused severe thrombocytopenia: a case report

Primary cardiac synovial sarcoma that was continuous with the mitral valve caused severe thrombocytopenia: a case report

... in nonspecific constitutional symptoms such as short- ness of breath, weight loss, and anaemia-related fatigue and malaise [3]. However, severe thrombocytopenia has very rarely been reported in association with cardiac ...

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Phosphoproteomic Profiling Reveals ALK and MET as Novel Actionable Targets across Synovial Sarcoma Subtypes.

Phosphoproteomic Profiling Reveals ALK and MET as Novel Actionable Targets across Synovial Sarcoma Subtypes.

... of sarcoma cell lines characterized to date and identified novel tyrosine phosphorylation patterns, enhanced tyrosine kinases in specific subtypes, and potential driver ...Aska-SS synovial sarcoma ...

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Primary synovial sarcoma of the kidney: a case report of complete pathological response at a Lebanese tertiary care center

Primary synovial sarcoma of the kidney: a case report of complete pathological response at a Lebanese tertiary care center

... tissue sarcoma (STS) is a rare malignant tumor of mesenchymal origin having an incidence of 2–3 cases per 100,000, thus contributing to less than 1% of all adult ma- lignancies [1, ...2]. Synovial ...

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Primary synovial sarcoma of the right heart involving the tricuspid valve in an elderly Chinese woman: a case report

Primary synovial sarcoma of the right heart involving the tricuspid valve in an elderly Chinese woman: a case report

... Synovial sarcoma (SS) is a distinctive entity, approxi- mately 90 % of which arise in the extremities, with a pre- dilection for the regions adjacent to large ...cardiac synovial sarcoma ...

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Case Report Synovial sarcoma of the neck masquerading as a malignant second branchial cleft cyst

Case Report Synovial sarcoma of the neck masquerading as a malignant second branchial cleft cyst

... Synovial sarcoma is a rare, malignant mesen- chymal neoplasm that accounts for approxi- mately 8% of all soft tissue ...neck synovial sarcoma reported by Jernstrom in 1954, only 3% to 5% of ...

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Original Article Primary synovial sarcoma of the kidney: a rare and easily misinterpreted renal entity

Original Article Primary synovial sarcoma of the kidney: a rare and easily misinterpreted renal entity

... to synovial sarcoma, sarcomatoid RCC show classic RCC components with adequate sampling, which are mostly clear cell RCC, less common are chromophobe RCC, papillary RCC, unclassified RCC and collecting ...

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Poor treatment outcomes with palliative gemcitabine and docetaxel chemotherapy in advanced and metastatic synovial sarcoma.

Poor treatment outcomes with palliative gemcitabine and docetaxel chemotherapy in advanced and metastatic synovial sarcoma.

... pleomorphic sarcoma. Synovial sarcoma is generally regarded as a relatively chemosensitive sarcoma subtype, although radiological response assessments in synovial sar- comas are ...

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