Systems biology and the modelling loop
Modelling Systems Biology: Intertwinement and the ‘Real'
... Drawing upon the later work of Maurice Merleau-Ponty, Aud Sissel Hoel and I have proposed a non-dualist ontology around the notion of the measuring body. 25 The measuring body is an instantiation of what Merleau-Ponty ...
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Modelling gene regulatory networks: systems biology to complex systems
... The main strengths of the Boolean network model are its analytical tractability and the ease and efficiency with which it can be simulated. The primary limi- tations of the model are its perceived lack of applicability ...
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A cell in the loop approach to systems modelling and simulation of energy storage systems
... battery systems employ a topology using cells in both series and parallel, a further application of CILS would investigate a parallel connection of differentially aged ...
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Cohesin biology meets the loop extrusion model
... by loop extrusion? First, two strands which are genomically and spatially proximal could be trapped when the hinge domain opens and held within the ring ...
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Mathematical modelling in systems biology : cell cycle regulation during leaf development in Arabidopsis
... Furthermore, modelling results indi- cated that pavement cell growth rate is strongly regulated during develop- ment, peaking during the early leaf expansion phase, followed by a rapid reduction until shut down at ...
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Computational analysis of the interferon alpha signalling pathway using a systems biology modelling approach
... 14 R ESULTS M ODELLING OF THE IFN ALPHA SIGNALLING PATHWAY To examine the IFN-α signalling pathway and in particular the kinetic behaviour of its key components, a novel IFN-α signalling model was developed (Figure 4, ...
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SYSTEM DYNAMICS MODELLING OF CLOSED LOOP SUPPLY CHAIN SYSTEMS FOR EVALUATING SYSTEM IMPROVEMENT STRATEGIES
... closed loop supply chain activities might resolve environmental problems such as waste ...closed loop supply chain processes should not only be a concern at the final phase of the product life cycle, but ...
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System Dynamics modelling of closed loop supply chain systems for evaluating system improvement strategies
... 23 measures in anticipation of evolving environmental performance requirements (Savaskan, Bhattacharya & Wassenhove 2004). Several examples of government regulations can be considered. In Japan any products ...
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Quantitative modelling biology undergraduate assessment
... QM BUGS I results. An initial item analysis for the 19 QM understanding items indicated that overall the assessment was relatively difficult for the students. Ten of the 19 items had the correct response as the most ...
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Agent-based modelling in synthetic biology
... the modelling of reactors as they can be treated as a uniform entity where the availability of substrates is similar ...algal systems to understand how aspects of a photo-bioreactor and the non-uniform ...
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Stem cell biology meets systems biology
... mathematical modelling approaches related to these fields was complemented by talks that presented upcoming technologies, such as genome-wide screening approaches or the construction and analysis of synthetic ...
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Enactments of Systems Biology
... to systems biology? My first encounter with systems biology was through a course I was invited to teach on interdisciplinary research ...tackle modelling in the life ...and ...
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Bioinformatics and Systems Biology
... computational biology, especially when closely linked to ...modern biology, ranging from gene definition and alternative splicing to protein sequence, structure, function and interaction networks, with ...
Vision Systems with the Human in the Loop
... vision systems that apply machine learning and automatic reasoning in order to learn from what they ...vision systems can rate the relevance and consistency of newly acquired knowledge, they can adapt to ...
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Interactomes, manufacturomes and relational biology: analogies between systems biology and manufacturing systems
... Anticipatory Systems At a fundamental level cells, like factory production systems contain anticipatory sys- tems, and much of the mathematics associated with factories can be exploited for sys- tems ...
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HPAC Primary Secondary Loop vs. Primary Loop Only Systems
... P/S- and PLOVF-System Electrical-Energy Usage Chilled-water-pumping electrical- energy savings. The top graph in Figure 7 shows potential annual chilled-water-pumping electrical- energy savings for a P/S-loop sys- ...
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A Systems and Synthetic Biology Framework for Regulatory Systems
... Biological systems consist of large numbers of interacting components and involve processes operating across a variety of spatial, temporal and biological ...scales. Systems biology aims at ...
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Modeling formalisms in Systems Biology
... Systems Biology has taken advantage of computational tools and high-throughput experimental data to model several biological ...in Systems Biology including Boolean networks, Bayesian ...
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Dupuytren's: a systems biology disease
... broblast biology research. In the top-down branch of the systems biology approach, data maps generated by large scale experiments fi rst need to be annotated and subjected to statistical analysis in ...
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Mechanical and Systems Biology of Cancer.
... and systems biology models can ultimately facilitate the design of therapeutic strategies aimed toward modulating cancer phenotypes with known biophysical features, such as migratory plasticity, remodeled ...
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