T-cell
Adult t cell leukemia/ lymphoma: from epidemiology to treatment
... (Human T cell leukemia / lymphoma virus type 1), an exogenous retrovirus discovered in humans, isolated in the United States, in ...+ T cells. These cells came from the peripheral blood of a patient ...
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Antiretroviral Therapy Reduces the Magnitude and T Cell Receptor Repertoire Diversity of HIV-Specific T Cell Responses without Changing T Cell Clonotype Dominance
... parent T cell populations ...epitope-specific T cell clonotypes to remain consistent despite a large decrease in the level of HIV antigen after the start of ...specific T cell ...
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T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice
... of T cells in the thymus, the maintenance of a peripheral T cell repertoire, and the activation of T cells in sec- ondary lymphoid organs rely on T cells recognizing antigen via the ...
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Superior T memory stem cell persistence supports long lived T cell memory
... identified T cells with a T SCM phenotype and stem cell–like properties in nonhuman ...Antigen-specific T SCM cells preferentially localized to LNs and were virtually absent from mucosal ...
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T cell receptor alpha , beta , and gamma genes in T cell and pre B cell acute lymphoblastic leukemia
... gamma-T cell receptor (TCR) gene activation within acute lymphoblastic leukemias (ALLs) that represent early stages of B and T cell ...
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Critical roles of Bim in T cell activation and T cell–mediated autoimmune inflammation in mice
... B cell lymphoma 2–interacting (Bcl2-interacting) mediator, maintains immunological tolerance by deleting autoreactive lymphocytes through ...Bim-deficient T cells had diminished cytokine production. Upon ...
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Identification of the human T cell lymphoma virus in B cell lines established from patients with adult T cell leukemia
... adult T cell ...expressed T cell markers, these two cell lines expressed B cell antigens and Ig light chains (kappa on CF-2, lambda on ...Human T cell lymphoma ...
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T cell repertoire remodeling following post transplant T cell therapy coincides with clinical response
... adoptive T cell therapy (ACT) approach to restore immunological control in patients with CMV compli- ...CMV-specific T cells using a customized peptide pool containing 30 HLA class I and ...
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The role of the T cell in autoimmune inflammation
... the T cell and some enhancing adhesion to target tissues, they all have the ability to augment the T-cell proliferative responses to antigenic ...
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Human T cell leukemia virus I associated T suppressor cell inhibition of erythropoiesis in a patient with pure red cell aplasia and chronic T gamma lymphoproliferative disease
... marrow T cell depletion. Patient Leu 2+ suppressor T cells spontaneously produced high titers of human gamma-interferon and resulted in a concentration-dependent selective inhibition (74-91%) of ...
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Survivin specific T cell receptor targets tumor but not T cells
... adoptive T cell therapy with genetically engi- neered αβ T cell receptors (TCRs) has resulted in encouraging responses in some patients ...to T cell activation, resulting in ...
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Alterations in cytotoxic and helper T cell function after infection of T cell clones with human T cell leukemia virus, type I
... OKT4+ T cell clone thus could simultaneously manifest both cytotoxic and helper T cell activities, and these activities were differentially affected after HTLV-I ...
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Relationship between systemic lupus erythematosus T cell subsets, anti T cell antibodies, and T cell functions
... differing T cell T4+/T8+ ratios and that the ratio correlated with clinical features of the ...blood T cell subsets in these patients were related to the specificity of anti-T ...
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The regulation of T cell homeostasis and autoimmunity by T cell–derived LIGHT
... activated T cells and downregulated on mature dendritic cells (DCs) ...on T, B, and other hematopoietic cells (31, ...costimulate T cell proliferation in combination with anti-CD3 mAb in vitro ...
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T regulatory cell chemokine production mediates pathogenic T cell attraction and suppression
... Future studies will be needed to define why Tregs from chil- dren with established T1D have a deficit in chemokine production. Some possibilities that could be tested include the following: defec- tive IL-2 signaling and ...
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T cell behavior at the maternal fetal interface
... of T cells at the maternal-fetal interface remains one of the most difficult problems in reproductive ...the T cells that populate the decidua have important roles in both normal and pathological ...
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Specific T cell activation in an unspecific T cell repertoire
... blood cell that circulate around our bodies, scanning for cellular abnormalities and infections (Figure ...Without T-cells, human immunity does not function optimally 1 ...of T-cell is present ...
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T cell homeostasis and systemic autoimmunity
... in T cell maturation may lead to a lymphocyte deficit in the periphery, and consequently, to the initiation of a home- ostatic, yet deleterious, anti-self ...
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T cell immunoengineering with advanced biomaterials
... enhanced T cell activation compared to cells stimulated using soluble agonist at the same ...efficient T cell proliferation for immunological assays has long relied on coating anti-CD3 and ...
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Compromised Influenza Virus-Specific CD8+-T-Cell Memory in CD4+-T-Cell-Deficient Mice
... was not reflected in any obvious (Fig. 2; Table 1) defect in the level of CTL effector function (in the BAL specimens) or in the capacity to produce IFN-␥ following short-term, in vitro stim- ulation with peptide (in the ...
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