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T cell response

Longitudinal Analysis of the Human T Cell Response during Acute Hantavirus Infection

Longitudinal Analysis of the Human T Cell Response during Acute Hantavirus Infection

... effector T cell response, we assessed regulatory T cells and the effect of in- hibitory receptors on responding effector T cells in the infected ...patients. T cells with a ...

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Antiviral T Cell Response Triggers Cytomegalovirus Hepatitis in Mice

Antiviral T Cell Response Triggers Cytomegalovirus Hepatitis in Mice

... T cell response parameters were evaluated in livers of BALB/c mice, comparing responses generated during lethal (v70) and sub- lethal (K181 ⫹ ) ...CD4 T cells were recovered from both groups ...

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The Cytomegalovirus-Specific CD4+ T-Cell Response Expands with Age and Markedly Alters the CD4+ T-Cell Repertoire

The Cytomegalovirus-Specific CD4+ T-Cell Response Expands with Age and Markedly Alters the CD4+ T-Cell Repertoire

... CD4 T-cell repertoire. As the CD4 T-cell response to CMV accumulates with age, it was felt important to assess the contribution of CMV carriage to the phenotype of the total CD4 ...

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The NK Cell Response to Mouse Cytomegalovirus Infection Affects the Level and Kinetics of the Early CD8+ T-Cell Response

The NK Cell Response to Mouse Cytomegalovirus Infection Affects the Level and Kinetics of the Early CD8+ T-Cell Response

... NK cell maturation and activation patterns in mice infected with WT MCMV or ⌬ m157 virus could not directly explain the differ- ences in the CD8 ⫹ T-cell ...immune response (37; reviewed in ...

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Human CD4+ T Cell Response to Human Herpesvirus 6

Human CD4+ T Cell Response to Human Herpesvirus 6

... CD4 T cell epitopes in HHV-6 is compli- cated by poor knowledge of the immune response to this virus, the low frequency of responding cells, the large number of proteins encoded by the HHV-6 genome ...

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Determining the Breadth of the Respiratory Syncytial Virus-Specific T Cell Response

Determining the Breadth of the Respiratory Syncytial Virus-Specific T Cell Response

... children. T cells play a critical role in clearing an acute RSV infection, as well as contributing to RSV-induced ...RSV-specific T cell response, using for the first time an overlapping ...

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Multiple specificities in the murine CD4+ and CD8+ T-cell response to dengue virus.

Multiple specificities in the murine CD4+ and CD8+ T-cell response to dengue virus.

... 1 T-cell clones isolated after primary den- gue virus infection, serotype-specific proliferative responses were more common than serotype-cross-reactive ...proliferative response to dengue-4 virus ...

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Dynamics of the Cytotoxic T Cell Response to a Model of Acute Viral Infection

Dynamics of the Cytotoxic T Cell Response to a Model of Acute Viral Infection

... acute response to a viral infection, viral antigen (Ag)-specific effector CD8 ⫹ T cell clones (also known as cy- totoxic T lymphocytes, or CTLs) become activated and expand as they recognize ...

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Promotion of a Subdominant CD8 T Cell Response during Murine Gammaherpesvirus 68 Infection in the Absence of CD4 T Cell Help

Promotion of a Subdominant CD8 T Cell Response during Murine Gammaherpesvirus 68 Infection in the Absence of CD4 T Cell Help

... CD4 T cells ...CD4 T cell help regulates this ...CD8 T cell response greatly expands well after the establishment of viral latency (35, ...inflationary response has been ...

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An Optimized CD8+ T-Cell Response Controls Productive and Latent Gammaherpesvirus Infection

An Optimized CD8+ T-Cell Response Controls Productive and Latent Gammaherpesvirus Infection

... ⴙ T cells effectively controlled acute replication of ␥ ...ⴙ T cells did not prevent the establishment of latency in the OTI/RAG ...OTI T cells in OTI/B6 animals, which express B cells—a major site ...

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Profile of human T cell response to leishmanial antigens  Analysis by immunoblotting

Profile of human T cell response to leishmanial antigens Analysis by immunoblotting

... a T cell response to a large and diverse pool of parasite ...of T cell immunoblotting appears to offer a powerful, rapid, and relatively simple approach to the identification of ...

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The specific T-cell response to antigenic peptides is influenced by bystander peptides

The specific T-cell response to antigenic peptides is influenced by bystander peptides

... IL-2 response of T cell hybridomas to a specific ...obtained T cell hybridomas responded very ...the T cell coreceptors CD28, CTLA-4, PD-1, ICOS, CD22 or LFA-1, ...

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A Highly Restricted T-Cell Receptor Dominates the CD8+ T-Cell Response to Parvovirus B19 Infection in HLA-A*2402-Positive Individuals

A Highly Restricted T-Cell Receptor Dominates the CD8+ T-Cell Response to Parvovirus B19 Infection in HLA-A*2402-Positive Individuals

... 2402-restricted T-cell response over time, the BV usage was markedly restricted even during acute ...new T-cell ...this response has not been compared with those of other HLA-A ⴱ ...

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Complex T-Cell Receptor Repertoire Dynamics Underlie the CD8+ T-Cell Response to HIV-1

Complex T-Cell Receptor Repertoire Dynamics Underlie the CD8+ T-Cell Response to HIV-1

... ⫹ T-cell response depends on the arsenal of T-cell receptor (TCR) clonotypes deployed to engage the targeted peptide-human leukocyte antigen class I (pHLA-I) ...⫹ T-cell ...

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FOXO3 Regulates the CD8 T Cell Response to a Chronic Viral Infection

FOXO3 Regulates the CD8 T Cell Response to a Chronic Viral Infection

... CD8 T cells was the result of diminished apoptosis and not of increased proliferation ...the cell surface ...CD8 T cell function and viral clearance in FOXO3L mice during the chronic phase of ...

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T Cell Response to Infection by the Porcine Reproductive and Respiratory Syndrome Virus

T Cell Response to Infection by the Porcine Reproductive and Respiratory Syndrome Virus

... 53. Feng, W. H., M. B. Tompkins, J. S. Xu, T. T. Brown, S. M. Laster, H. X. Zhang and M. B. McCaw. Thymocyte and peripheral blood T lymphocyte subpopulation changes in piglets following in utero ...

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Characterization of the human T cell response to in vitro CD27 costimulation with varlilumab

Characterization of the human T cell response to in vitro CD27 costimulation with varlilumab

... promote T cell dys- function or apoptosis through CD27 signaling in vitro [34, ...on T cells isolated from healthy individuals, cultured under controlled conditions, and demonstrated a ro- bust ...

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The characterisation of a T cell response to human rhinovirus

The characterisation of a T cell response to human rhinovirus

... 1994), as well as a transient production in Th2 clones (Yssel et al. 1994; Manetti et al. 1994). Consequently in a number of studies, the Thl priming effects of IL-12 have been shown to be dependent on the presence of ...

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Functional management of an antiviral cytotoxic T-cell response.

Functional management of an antiviral cytotoxic T-cell response.

... CTL response recognized almost all variant peptides ...CTL response with a monoclonal response, TCR-transgenic mice expressing a TCR specific for LCMV were also infected with ...of T cells ...

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T-cell response to cottontail rabbit papillomavirus structural proteins in infected rabbits.

T-cell response to cottontail rabbit papillomavirus structural proteins in infected rabbits.

... Here we have shown that the progression of papillomas to carcinomas is associated with an increased cellular immune response to viral structural proteins.. A similar increase in the resp[r] ...

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