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T-cell responses

Ly6Chi monocytes regulate T cell responses in viral hepatitis

Ly6Chi monocytes regulate T cell responses in viral hepatitis

... + T cell responses are essential for viral clearance, it remains largely unknown what regulates T cell–mediated viral ...anti-viral T cell immunity would be critical for ...

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CD160 isoforms and regulation of CD4 and CD8 T cell responses

CD160 isoforms and regulation of CD4 and CD8 T cell responses

... CD8 T-cell ...+ T-cell activation upon binding to MHC-I, or a co- inhibitory role on CD4 + T-cell activation upon binding to ...on T-cell activation, herein CD4 + ...

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Impact of IL-27 on regulatory T cell responses

Impact of IL-27 on regulatory T cell responses

... inflammatory responses during toxoplasmosis as well as other infections or autoimmune ...regulatory T (Treg) cells are critical to limit inflammation, their role during toxoplasmosis is controversial ...

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Human T-Cell Responses to Vaccinia Virus Envelope Proteins

Human T-Cell Responses to Vaccinia Virus Envelope Proteins

... memory T cells from vaccinated donors. VACV-specific T-cell lines (TCLs) were prepared from peripheral blood mononuclear cells (PBMC) from four ...⫹ T-cell responses. ...

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Glatiramer acetate (Copaxone) therapy induces CD8+ T cell responses in patients with multiple sclerosis

Glatiramer acetate (Copaxone) therapy induces CD8+ T cell responses in patients with multiple sclerosis

... Multiple sclerosis (MS) is an inflammatory, demyeli- nating disorder of the CNS with varied clinical presen- tations that range from clearly defined relapses and remissions (RRMS) to slow accumulation of disability with ...

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Asian Elephant T Cell Responses to Elephant Endotheliotropic Herpesvirus

Asian Elephant T Cell Responses to Elephant Endotheliotropic Herpesvirus

... elephant T cell responses at the cellular level have not been explored, in part because there are limited reagents to detect phenotypic (cell surface markers) and functional characteristics ...

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Human T-Cell Responses to the Glucosyltransferases of Streptococcus mutans

Human T-Cell Responses to the Glucosyltransferases of Streptococcus mutans

... the responses in saliva and serum induced by this protein are lower than those induced by ...ferent T-cell ...immune responses away from molecules essential for adherence and colonization to ...

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Antigen-Specific T-Cell Responses of Leprosy Patients

Antigen-Specific T-Cell Responses of Leprosy Patients

... human T-cell antigens of Mycobacterium leprae could improve treatment and help to disrupt the transmission of leprosy by directing diagnosis and vaccine ...for T-cell recall responses, ...

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Mature T cell responses are controlled by microRNA 142

Mature T cell responses are controlled by microRNA 142

... regulating T cell responses. T cell development was not affected in animals with a targeted deletion of Mir142; however, T cell proliferation was markedly reduced ...

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Regulation of autoimmune and anti‐tumour T‐cell responses by PTPN22

Regulation of autoimmune and anti‐tumour T‐cell responses by PTPN22

... immune cell types including lymphocytes, granulocytes and myeloid ...regulating T cell activation and effector ...anti-tumour T cell ...

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Polyfunctional T Cells Accumulate in Large Human Cytomegalovirus-Specific T Cell Responses

Polyfunctional T Cells Accumulate in Large Human Cytomegalovirus-Specific T Cell Responses

... individuals. T-cell responses to the CMV proteins pp65 and IE-1 were tested in all seropositive individuals and all individuals for whom serology was not available at the time of testing, which ...

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Reduced Hepatitis B Virus (HBV)-Specific CD4+ T-Cell Responses in Human Immunodeficiency Virus Type 1-HBV-Coinfected Individuals Receiving HBV-Active Antiretroviral Therapy

Reduced Hepatitis B Virus (HBV)-Specific CD4+ T-Cell Responses in Human Immunodeficiency Virus Type 1-HBV-Coinfected Individuals Receiving HBV-Active Antiretroviral Therapy

... HBV-specific T-cell responses, an overlapping peptide library was made by using the consensus sequence for genotype A HBV ...⫹ T cells (8, 28, ...for responses to genotypes B to D to be ...

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Effect of anti-IgE therapy on food allergen specific T cell responses in eosinophil associated gastrointestinal disorders

Effect of anti-IgE therapy on food allergen specific T cell responses in eosinophil associated gastrointestinal disorders

... specific T cell ...specific T cells, as well as decreased in vitro allergen specific T cell ...mast cell and basophil acti- vation in vivo, [8], which may result in decreased ...

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Age-related differences in polyfunctional T cell responses

Age-related differences in polyfunctional T cell responses

... on cell-mediated immunity in aging has been either on antigen specific vaccine or viral ...CD8+ T cells ...CD8+ T-cell subsets in older adults vaccinated with influenza ...related T ...

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MyD88 Intrinsically Regulates CD4 T-Cell Responses

MyD88 Intrinsically Regulates CD4 T-Cell Responses

... inflammatory responses in innate immune cells, but its role in the regulation of the adap- tive immune response and immunopathology is poorly defined (6, 23, ...affect T-cell responses? The ...

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Increased CD8+ T cell responses to apoptotic T cell-associated antigens in multiple sclerosis

Increased CD8+ T cell responses to apoptotic T cell-associated antigens in multiple sclerosis

... effector T cells undergoing apoptosis after performing their functions in inflammatory diseases, and the possible role of these apoptotic cells in ...totic T cells include prominent caspase-cleaved cellular ...

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B Cell Requirement for Robust Regulatory T Cell Responses to Friend Retrovirus Infection

B Cell Requirement for Robust Regulatory T Cell Responses to Friend Retrovirus Infection

... Regulatory T cells (Tregs) are immunosuppressive cells of the immune system that control autoimmune ...⫹ T cell responses. Unlike conventional T cells, the responding Tregs are not ...

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Podoplanin negatively regulates CD4+ effector T cell responses

Podoplanin negatively regulates CD4+ effector T cell responses

... on T cells may limit the persistence of aggressive T effector cells in the target ...gerated T cell responses, as suggested by inflammatory infiltrates in multiple organs in globally ...

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Recall T cell responses to bluetongue virus produce a narrowing of the T cell repertoire

Recall T cell responses to bluetongue virus produce a narrowing of the T cell repertoire

... bulk T cell responses corre- late weakly with the control of virus replication, whereas T cell responses to subdominant epitopes can play an important role in limiting infection ...

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Cd8+ T-Cell Responses in a Th2-Polarized Inflammatory Setting

Cd8+ T-Cell Responses in a Th2-Polarized Inflammatory Setting

... CD4+ T cells, it is increasingly appreciated that CD8+ T cells in these settings may either contribute to or reduce ...CD8+ T- cell responses in an inflammatory setting, mice deficient ...

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