T helper cell
Identification of global regulators of T-helper cell lineage specification
... CD4+ T cells ...in T-helper cell lineage ...of T-helper cell ...early T- helper cell ...in T-helper cell ...
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Limited Breadth of a T-Helper Cell Response to a Human Immunodeficiency Virus Envelope Protein
... gp120-specific T-helper cell response so narrow in 1035 envelope-primed C57BL/6 mice? T-helper responses to the PKVSFEPIPIHYCAP region have been previously identified in independent ...
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Decoy receptors in the regulation of T Helper cell type 2 response
... the Fc domain has been shown to slow in vivo clearance of TNFR-Fc fusion proteins. Now that this novel regulatory role for IL-13R 2 has been identified, it will be important to address the mechanism by which this ...
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T4+ T helper cell function in vivo: differential requirement for induction of antiviral cytotoxic T-cell and antibody responses.
... Depletion of T4+ cells caused a pronounced suppression of antiviral antibody response 20-fold decrease but had minimal effect on virus-specific CTL response 90% of T helper cells, anti-L[r] ...
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T helper cell mediated-tolerance towards fetal allograft in successful pregnancy
... + T helper cells can recognize paternal HLA-C molecules only if HLA-C-derived peptides are presented by maternal APCs [1], these results are consistent with the possibility that, T cells in pregnant ...
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BATF regulates collagen induced arthritis by regulating T helper cell differentiation
... with protocols approved by the Animal Care and Ethics Committees of the Gwangju Institute of Science and Tech- nology. CIA was induced by a standard protocol [19, 20]. Mice were intradermally injected with incomplete ...
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Induction of rabies virus-specific T-helper cells by synthetic peptides that carry dominant T-helper cell epitopes of the viral ribonucleoprotein.
... To determine whether RNP-specific T-helper cells cross-reacted with the RNP or N protein from different rabies or rabies-related viruses, BALB/c mice were immunized with ERA BPL s.c., an[r] ...
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Myocardial infarction triggers cardioprotective antigen specific T helper cell responses
... T cell samples and the high frequencies found for some sequences (37) indicated a clonal expansion of these ...cardiac T cells had the highest Gini scores among all the groups (Figure 6C, P < ...
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Vaccine efficacy and T helper cell differentiation change with aging
... CD4 T cell ...antibody-dependent cell-mediated cytotoxicity [23]. Responding CD4 T cells differentiate into T follicular helper (Tfh) cells, which are required for germinal ...
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Identification of a T-helper cell epitope on the rotavirus VP6 protein.
... that are relevant for protection. Moreover, particular attention must be paid to heterotypic responses, since in humans there are at least four different epidemiologically important rota- virus G serotypes (35). The ...
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Influence of epitope polarity and adjuvants on the immunogenicity and efficacy of a synthetic peptide vaccine against Semliki Forest virus.
... Humoral response to either the B-cell epitope peptide B, the T-helper cell epitope peptide T or the combination peptide T-B, using Quil A as an adjuvant Peptide used for immunization' B [r] ...
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Immunoregulatory subsets of the T helper and T suppressor cell populations in homosexual men with chronic unexplained lymphadenopathy
... major helper subset for B cell responses, is normally represented in lymphadenopathy ...T4 T cell ...T8 T cells: the T8:TQ1- or T8:Leu-8- subset is elevated, whereas the T8:TQ1+ or ...
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Multiple myeloma presenting as cutaneous leukocytoclastic vasculitis and eosinophilia disclosing a T helper type 1/T helper type 2 imbalance: a case report
... 10–340 IU/mL), and 515 mg/dL (normal range, 3.3– 19.4 mg/dL), respectively. Serum protein electrophoresis disclosed a monoclonal spike in the γ-globulin region and urine electrophoresis also revealed a monoclonal spike. ...
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Helper T cells in flavivirus infection
... Recently the YF, West Nile dengue type 2 al., DEN2 encephalitis of yellow fever Rice et amino {SLE and virus genomes have been investigated 1985, 1986; Dalgarno et al., 1986a; amino-term[r] ...
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A regulatory effect of IL 21 on T follicular helper like cell and B cell in rheumatoid arthritis
... Moreover, IL-21 can directly act on B cells. IL-21 co- stimulation is capable of promoting plasma cells differ- entiation from CD27 + memory B cells, inducing class switch recombination and stimulating poorly responsive ...
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Transcriptional Regulation of T Helper 17 Cell Differentiation
... of T helper subsets, Th17, has recently been identified as an IL- 17-producing CD4+ Th cell, and its functions and regulatory mechanisms have been extensively characterized in immune ...Th17 ...
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Cell-Mediated Immune Response to Human Papillomavirus Infection
... Langerhans cell migration, and IL-10, produced by keratinocytes, which acts as an inhibitor of Langerhans cell migration ...Langerhans cell maturation into mature dendritic cells ...cervical ...
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Follicular helper T cell signature in type 1 diabetes
... target cell populations, including B cells, CD8 T cells, NK cells, and dendritic ...follicular helper T (Tfh) cells represent likely ...reassess T cell dif- ferentiation in a ...
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Ubiquitylation Regulates Cd4+ T Cell Activation and Effector Differentiation to Shape the Immune Response
... Jurkat T cells with Stub1 knocked-down via RNAi show decreased phosphorylation of IκBα, ubiquitylation of CARMA1 and transcription of IL-2 mRNA in vitro (Wang et ...regulatory T cells, Stub1 has been shown ...
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Local Expression of T Cell Subsets in Sensitized and Unsensitized Experimental Cystic Echinococcosis.
... In control unsensitized group, hydatid cystic lesions were detected in all animals included in the group with intact morphological features and scolices. In sensitized group, cysts were detected in 5 out of 10 animals ...
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