T helper type 2 (Th2)
Multiple myeloma presenting as cutaneous leukocytoclastic vasculitis and eosinophilia disclosing a T helper type 1/T helper type 2 imbalance: a case report
... chain type) with leukocytoclastic vasculitis and ...a T helper type 1/T helper type 2 imbalance and T regulatory cells, and was successfully treated with ...
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SOCS2 regulates T helper type 2 differentiation and the generation of type 2 allergic responses
... These type two cytokines drive elevated serum IgE and infiltration of Th2 cells, eosinophils, and baso- phils, which have been observed in patients with asthma and AD (Venge et ...
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Plasma levels of monokine induced by interferon-gamma/chemokine (C-X-X motif) ligand 9, thymus and activation-regulated chemokine/chemokine (C-C motif) ligand 17 in children with Kawasaki disease
... AST: Aspartate aminotransferase; C: Cys; CAA: Coronary artery aneurysm; CAL: Coronary artery lesions; CC: Cys-Cys; CK-MB: Creatine kinase-MB; CRP: C-reactive protein; CXC: Cys-X-Cys; CX3C: Cys-X-3Cys; EDTA: Ethylene ...
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Distinct gene expression profiles of human type 1 and type 2 T helper cells
... secreting Th2, respec- ...human type 1 and type 2 Th cells are still largely ...of Th2 cells remained ...polarized T helper cells and describe the comparative analysis of ...
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Purified protein derivative of Mycobacterium tuberculosis and excretory secretory antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production
... that T cells with stable Th1 or Th2 functional pattern exist not only in mice but also in humans and suggest that in the course of natural immunization certain infectious agents preferentially expand ...
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Follicular helper T cell signature in type 1 diabetes
... the type of immune response that underlies autoim- mune tissue destruction is a critical step in designing appropri- ate immunomodulatory ...of type 1 diabetes (T1D), current dogma holds that Th1 cells ...
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Imbalanced shift of cytokine expression between T helper 1 and T helper 2 (Th1/Th2) in intestinal mucosa of patients with post-infectious irritable bowel syndrome
... predominant type (C-IBS) or diarrhea-predominant type (D-IBS) according to the Roman III diagnostic criteria [7] were recruited for this study, including 20 PI-IBS patients with a history of acute enteritis ...
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Local Expression of T Cell Subsets in Sensitized and Unsensitized Experimental Cystic Echinococcosis.
... of Th2 cells (Lundi et ...regulatory T cells (Babu et al. 2005). In addition to cytotoxic T cell which is known as cytotoxic T lymphocyte, cytolytic T cell, CD8+ T- cells or ...
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Decoy receptors in the regulation of T Helper cell type 2 response
... the Th2 cytokine receptors have been identified in serum or urine, but their functional importance remains ...IL-13R 2 appears to have evolved to specifically inhibit the IL-13–mediated func- tions, though ...
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Determinant in Human Immunodeficiency Virus Type 1 for Efficient Replication under Cytokine-Induced CD4+ T-Helper 1 (Th1)- and Th2-Type Conditions
... IL-4-induced Th2-type culture cells with chi- meric ...IL-4-induced Th2-type culture with NL4-3, JR-CSF, JR-FL, or recombinant ...maintain Th2-type conditions. Figure 2 ...
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Treatment with depleting CD4 monoclonal antibody results in a preferential loss of circulating naive T cells but does not affect IFN gamma secreting TH1 cells in humans
... ducing T helper 2 (TH2)-type cells in the anti-CD4 treated group was observed, numbers of IFN- g –producing T helper 1 (TH1)-type cells remained stable, resulting ...
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Epidermal Growth Factor Receptor Expression Licenses Type 2 Helper T Cells to Function in a T Cell Receptor Independent Fashion
... that Th2 cells contribute to worm expulsion at the site of infection (Anthony et ...how Th2 cells are activated at the site of ...and Th2 cells (Oliphant et ...that Th2 cells, similar to ILC2, ...
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T-helper-1, T-helper-17, T-regulatory lymphocytes in hypertensive patients with diabetes mellitus type 2 or impaired glucose tolerance: association with clinical and metabolic parameters in a case control study
... Another clinical parameter closely related to immune factors in DM2 patients was glomerular filtration rate. It was inversely related to numbers of FoxP3+ Treg- lymphocytes, numbers of Th17- and IL-23R+ cells in intact ...
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T-helper 1 versus T-helper 2 lymphocyte immunodysregulation is the central factor in genesis of Burkitt lymphoma: hypothesis
... and T-cell mediated immune responses including child- hood HIV/AIDS in the African setting, adults with advanced HIV/AIDS in the Western setting and in post- transplant lymphoproliferative disorders ...of ...
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Relevance of tumor-infiltrating lymphocytes in breast cancer
... and, accordingly, a subset of patients with breast cancer present clear evidence of immune suppression and aggres- sive disease progression, potentially driven by mechanisms of tumor tolerance [3, 4]. In the elimination ...
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Th1/Th17 polarization persists following whole cell pertussis vaccination despite repeated acellular boosters
... or 2 decades despite continued boosts of both populations with aP (4–5 additional aP vaccinations are routinely administered in childhood and adolescence, and beginning in 1996, emergency room tetanus vaccinations ...
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Polarization of Allogeneic T-Cell Responses by Influenza Virus-Infected Dendritic Cells
... the T-cell ...and T cells treated with an amount of NA that was even smaller than that measured in supernatants of DC infected with high doses of PR8 released sialic acid into the ...When T cells ...
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How to Orient Yourself in the Wilderness
... abnormal T cell priming by RSV vaccination was demonstrated to be responsible for RSV disease (33, 95, ...producing T cells were shown to contribute to RSV protection as well as disease ...producing ...
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Abnormal T regulatory cells (Tregs: FOXP3+, CTLA 4+), myeloid derived suppressor cells (MDSCs: monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC
... the Th2 profile (IL-4, IL-5) was substantially and significantly increased; IL-10 was non significantly increased, and IL-6 showed no ...and Th2 profiles, except for IL-4, which resembled levels found in ...
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Decreased T helper 17 cells in tuberculosis is associated with increased percentages of programmed death ligand 1, T helper 2 and regulatory T cells
... + T lymphocytes through interactions between programmed cell death ligand-1 (PD-L1) from dendritic cells and PD-1 on T cells ...of T cell regulators, and the intracellular tail con- tains two ...
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