T pallidum
Immunoglobulin G subclasses of fluorescent anti Treponema pallidum antibodies: evidence for sequential development of specific anti T pallidum immunoglobulin G responses in patients with early syphilis
... A second observation often cited to support immune suppression during early syphilis is the absence of positive skin reactions to treponemal antigens in patients with primary and seconda[r] ...
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Borrelia burgdorferi and Treponema pallidum: a comparison of functional genomics, environmental adaptations, and pathogenic mechanisms
... Treponema pallidum subspecies pallidum, the agent of venereal ...contrast, T. pallidum must be grown in the testicles of live rabbits to obtain bacte- ria for experimental use ...
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Examining the validity and reliability of the Activities Specific Balance Confidence Scale 6 (ABC 6) in a diverse group of older adults
... of T. pallidum antibodies in human serum or ...serum, T. pallidum antibodies specifically were bound to the immunized antigens on the ...
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Evaluation of a PCR Test for Detection of Treponema pallidum in Swabs and Blood
... the T. pallidum genome in patients with primary and secondary syphilis, with a concordance of ...of T. pallidum, as previously shown ...which T. pallidum was detected only by the ...
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Detection of the A2058G and A2059G 23S rRNA Gene Point Mutations Associated with Azithromycin Resistance in Treponema pallidum by Use of a TaqMan Real Time Multiplex PCR Assay
... Sensitivity and specificity of the real-time triplex PCR. The limit of detection of the triplex PCR assay was 1 to 10 genomic copies per reaction mixture with serial dilutions of purified genomic DNA or 629-bp 23S rRNA ...
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Lipoprotein-Dependent and -Independent Immune Responses to Spirochetal Infection
... Despite numerous reports documenting the proinflamma- tory activities of microbial lipoproteins and corresponding syn- thetic analogs, strategies for assessing the in situ biological activities of these proinflammatory ...
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Evidence for Posttranslational Protein Flavinylation in the Syphilis Spirochete Treponema pallidum: Structural and Biochemical Insights from the Catalytic Core of a Periplasmic Flavin Trafficking Protein
... Reconstitution of the T. pallidum flavinylation reaction by Ftp_Tp in Escherichia coli. Recently, it has been reported that the Ftp proteins of Vibrio harveyi (Ftp_Vh) and Klebsiella pneumoniae (Ftp_Kp) can ...
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Detection of Treponema pallidum by a sensitive reverse transcriptase PCR
... of T. pallidum, but none of these has shown a clear advantage in sensitivity over ...23 T. pallidum organisms when RNA equivalents are used to make ...
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Treponema pallidum Surface Immunofluorescence Assay for Serologic Diagnosis of Syphilis
... of T. pallidum. Treponema pallidum subsp. pallidum (Nichols strain), originally purchased from the Statens Serum Institut, Copenhagen, Denmark, was maintained in adult male New Zealand White ...
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Development of tissue inflammation accompanied by NLRP3 inflammasome activation in rabbits infected with Treponema pallidum strain Nichols
... model, T. pallidum infec- tion presents with the progression of macrophage activa- tion and mononuclear cell infiltration at the sites of the experimental inoculation ...in T. pallidum ...
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Rapid Multiplexed Immunoassay for Simultaneous Serodiagnosis of HIV 1 and Coinfections
... We note that the human IgG and anti-human IgG control spots have been designed to give fluorescence signal compara- ble to that of a typical seropositive sample. Obviously, both total human IgG and the goat anti-human ...
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Diagnosing Genital Ulcer Disease in a Clinic for Sexually Transmitted Diseases in Amsterdam, The Netherlands
... T. pallidum. In most countries around the world, syphilis ranks as the second most frequent cause of GUD, with a worldwide prevalence in patients of 2 to 25%, depending on the study population. In the STD ...
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Alzheimer's disease - a neurospirochetosis. Analysis of the evidence following Koch's and Hill's criteria
... Spirochetes are able to evade host defense mechanisms and establish latent and slowly progressive chronic infec- tion. They employ a broad range of strategies to overcome antigenic recognition, phagocytosis and ...
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Evaluation of the Recombinant Protein TpF1 of Treponema pallidum for Serodiagnosis of Syphilis
... Treponema pallidum subsp. pallidum, and diagnosis with sensitive and specific meth- ods is a challenging process that is important for its prevention and ...the T. pallidum Nichols strain and ...
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Specific immunofluorescence staining of Treponema pallidum in smears and tissues
... pallidum in chancre smears 15 can easily be stained with specific fluorescein-labeled anti- T.pallidum conjugate absorbed with Treponema phagedenis.. However, this conjugate has not been[r] ...
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Long Term In Vitro Culture of the Syphilis Spirochete Treponema pallidum subsp pallidum
... the T. pallidum subspecies, ...isolate T. pallidum and other pathogenic Treponema directly from tissues or body fluids using the in vitro culture ...vitro-cultured T. pallidum ...
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A longitudinal evaluation of Treponema pallidumPCR testing in early syphilis
... Taylor Square Private Clinic was established in 1981 as Australia’s first private sexual health clinic and has one of the highest case-loads of HIV-infected MSM patients in Australia [11]. All high-risk patients are ...
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Treponema pallidum Immunohistochemistry is positive in human intestinal Spirochetosis
... that Brachyspira species are capable of tissue invasion. However, it is not possible to definitively confirm the species of these organisms within the lamina propria in view of the fact that the T. pallidum ...
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Sequence Variation of Rare Outer Membrane Protein β Barrel Domains in Clinical Strains Provides Insights into the Evolution of Treponema pallidum subsp pallidum, the Syphilis Spirochete
... Treponema pallidum subsp. pallidum, has undergone a dramatic resurgence in the United States, particularly among men who have sex with men ...diverse T. pallidum subsp. pallidum strains ...
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THE INFLUENCE OF TERATOGENS IN THE DEVELOPMENT OF MENTAL DISORDERS - eSciPub Journals
... But it stands out also that congenital syphilis may be responsible for neurological damage due to Treponema pallidum trend breaking into the irrigation system and brain drain blood [r] ...
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