T47D cells
Nobiletin Increased Cytotoxic Activity Of Doxorubicin On Mcf-7 Cells But Not On T47d Cells
... MCF-7 cells showed lower sensitivity to doxorubicin than T47D cells ...MCF-7 cells caused cells resistance to apoptosis triggered by ...caused cells evading the apoptosis ...
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PCP4/PEP19 promotes migration, invasion and adhesion in human breast cancer MCF-7 and T47D cells
... MCF-7 cells, loss of Bmi-1 reduced the mRNA and protein expression of PCP4/PEP19, whereas PCP4/ PEP19 knockdown decreased Bmi-1 mRNA and protein expression (Figures 3C and ...in cells treated with Bmi-1 or ...
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Epidermal growth factor suppresses induction by progestin of the adhesion protein desmoplakin in T47D breast cancer cells
... of T47D, ZR-75 and MCF-7 ...of T47D cells to R5020, a clear increase in desmoplakin I and II protein expression was found ...to T47D and ZR75 cells, progestin also induced desmoplakin ...
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Preclinical modeling of combined phosphatidylinositol 3 kinase inhibition with endocrine therapy for estrogen receptor positive breast cancer
... HER2-negative cells, however, and it was not clear how PIK3CA mutation impacts PI3K inhibitor sensitivity in the setting of estrogen ...mutant cells was not ...and T47D cells but not in BT-483 ...
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DOCKING, SYNTHESIS AND CYTOTOXIC TEST ON HUMAN BREAST CANCER CELL LINE T47D OF N (PHENYLCARBAMOTHIOYL) BENZAMIDE
... using T47D the breast cancer ...for T47D cells to obtain a series of standard working solution. T47D cancer cell culture is prepared in microplate with 96 wells in a form of a cell suspension ...
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Mucoxin (Acetogenin) Induce Expression of Pro-Apoptosis Proteins, Bax and P53, in T47D Breast Cancer Cells
... the T47D cell samples using easy-spin™ (DNA free) total RNA extraction kit from Intron ...the T47D cells were determined by quantitative PCR (qPCR) methods using RealMOD™ Green Real-time PCR Kit from ...
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Loss of plakoglobin promotes decreased cell-cell contact, increased invasion, and breast cancer cell dissemination in vivo
... of cells from the primary tumor ...MCF7 cells growing as spheroids on agar, demonstrating that these cells were able to form exten- sive bonds with surrounding ...Control T47D, which expressed ...
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Nuclear cathepsin D enhances TRPS1 transcriptional repressor function to regulate cell cycle progression and transformation in human breast cancer cells
... As Cath-D does not have a nuclear localization signal (NLS), we investigated whether mature Cath-D reaches the nucleus by binding to TRPS1. TRPS1 silencing did not prevent Cath-D accumulation in the nucleus of ...
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The dual role of asporin in breast cancer progression
... Asporin has been reported as a tumor suppressor in breast cancer, while asporin- activated invasion has been described in gastric cancer. According to our in silico search, high asporin expresion associates with ...
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Journal of Applied Pharmaceutical Science
... on T47D cells reduced the expression of Bcl-2, thus increased the sensitivity of the cancer ...of T47D cells with Doxo for 24 hours exhibited an increase of phosphorylated Akt ...The ...
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Downregulation of the tumor suppressor miR 16 via progestin mediated oncogenic signaling contributes to breast cancer development
... mPro-transfected T47D-Y cells), the same as Stat3, and also appears to be modulated by PR-mediated transcrip- tional tethering mechanisms (Figure 2C, C587A-PR-trans- fected T47D-Y ...and T47D ...
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Ovarian Follicle Disaggregation to Assess Granulosa Cell Viability
... lines; T47D, 184B5, (a) and KGN (b) were assessed using a standard Trypan Blue Exclusion ...KGN cells, or 930 viable T47D cells were made up to 100 µL, then subjected to four 1:2 ...of ...
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The role of estrogen receptor alpha in mediating chemoresistance in breast cancer cells
... in T47D breast cancer cells; rather, it increased sensitivity to chemother- apeutic agents in these ...in T47D cells increased after being treated with E2 for 12 days and that fulvestrant ...
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Antiproliferative and apoptotic effects of selective phenolic acids on T47D human breast cancer cells: potential mechanisms of action
... on T47D cell growth, we have concentrated on two out of the six phenolic acids: caffeic acid, which is the most potent, and PAA, which is a precursor for the synthe- sis of other more complex molecules ...
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Original Article IMP3 expression is associated with epithelial-mesenchymal transition in breast cancer
... lines. T47D-IMP3 cells exhibited a slight altera- tion in morphology, growing in elongated indi- vidual cells rather than tight aggregates (Figure ...231-siRNA-IMP3 cells grew in more ...
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Fbxo22 mediated KDM4B degradation determines selective estrogen receptor modulator activity in breast cancer
... Fbxo22-KO cells formed tumors of comparable size in all transplanted mice, indicating that Fbxo22 deletion, per se, did not affect T47D growth in female NOD/Scid ...Fbxo22-KO cells after TAM treat- ...
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<p>Circular RNA hsa_circ_0072309 inhibits proliferation and invasion of breast cancer cells via targeting miR-492</p>
... brief, the coding sequence of hsa_circ_0072309 was inserted into the PLCDH-cir vector (Ribobio, Guangzhou, China). The lentiviral vector was constructed by Hanbio (Shanghai, China). Transfection was performed in ...
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Trichostatin A enhances acetylation as well as protein stability of ERα through induction of p300 protein
... cancer cells [16,17]. When MCF7 or T47D cells were treated with TSA for a prolonged period, we also observed a similar downregulation of ERα, indicating that TSA may affect ERα activity through at ...
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<p>TRIM11 promotes proliferation and glycolysis of breast cancer cells via targeting AKT/GLUT1 pathway</p>
... in T47D cells trans- fected with siTRIM11-1 or ...transfected cells (Figure ...BT474 cells transfected with siTRIM11-1 or siTRIM11-2 (Figure 3G and ...
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Anti-Proliferative and Apoptotic Effects of Mucoxin (Acetogenin) in T47D Breast Cancer Cells
... the T47D cell apoptosis after mucoxin treatment in each hour group is ilustrated in Figure ...of T47D cells of each exposure hour group are presented in Table ...apoptotic cells between the ...
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