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target cell

Retrovirus infection: effect of time and target cell number.

Retrovirus infection: effect of time and target cell number.

... the target cell number, there was little effect on the extent of ...altering target cell number did not increase the effi- ciency of infection of a recombinant retrovirus ...of cell ...

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The Cell Biology of Systemic Hyperinflammation Resulting from Failed Cytolytic Target Cell Killing

The Cell Biology of Systemic Hyperinflammation Resulting from Failed Cytolytic Target Cell Killing

... the target cells revealed that one likely reason for cytokine hypersecretion in the latter is sustained Ca 2+ signaling, and this is related to the failure of the cells to disengage from their un- killed targets, ...

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Real Time Cell Analysis of Model Target Cell Lines Exposed to Purified Lipoprotein (a)

Real Time Cell Analysis of Model Target Cell Lines Exposed to Purified Lipoprotein (a)

... in vivo, as it might indicate a preferential cell processing for small isoforms by hepatic cells. Deposition and accumulation of Lp(a) particles in the atherosclerotic blood vessel wall exacerbates atherosclerotic ...

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Membrane Fusion Tropism and Heterotypic Functional Activities of the Nipah Virus and Hendra Virus Envelope Glycoproteins

Membrane Fusion Tropism and Heterotypic Functional Activities of the Nipah Virus and Hendra Virus Envelope Glycoproteins

... glioblastoma cell line, as target cells. The MT2 cell line is the first T-cell line examined that appears to express the HeV and NiV ...U373 cell line supported the highest level of ...

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Yersinia proteins that target host cell signaling pathways

Yersinia proteins that target host cell signaling pathways

... The other effector involved in antiphagocytosis, YopH, is homologous to eukaryotic tyrosine phosphatases (18) and has the highest activity of all tyrosine phosphatases known today (19). High expression of YopH alone is ...

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Cell to Cell Spreading of HIV 1 in Myeloid Target Cells Escapes SAMHD1 Restriction

Cell to Cell Spreading of HIV 1 in Myeloid Target Cells Escapes SAMHD1 Restriction

... through cell fusion during coculture with infected T cells were certainly excluded from the analysis performed by Puigdomènech and colleagues ...through cell fusion of infected T cells with iDC ...this ...

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LIPOSOMES: AN OVERVIEW

LIPOSOMES: AN OVERVIEW

... of target recognition molecules on lipid ...a target cell such as a tumor cell and specific molecules in the body (antibodies, proteins, peptides ...

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A New Traffic Congestion Forecast Model Based on City Cell

A New Traffic Congestion Forecast Model Based on City Cell

... the target city cell, it has four sides, for each edge E, the target cell flow from E to the adjacent cell, forming an escape force (Figure 3 F1), the adjacent cell from the edge ...

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An Autonomous Exploration Strategy for Cooperative Mobile Robots

An Autonomous Exploration Strategy for Cooperative Mobile Robots

... In all of the above mentioned works, there is no serious solution for the problem of overlap amongst the ro- bots. Moreover, the presented exploration algorithms have not been tested with different environments or with ...

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Herpes simplex virus-infected human fibroblasts are resistant to and inhibit cytotoxic T-lymphocyte activity.

Herpes simplex virus-infected human fibroblasts are resistant to and inhibit cytotoxic T-lymphocyte activity.

... The inhibition of anti-HSV CTL lytic activity by incubation with HSV-FB ranged from 61% at an effector/ target cell ratio of 50:1 to 81% at an effector/target cell ratio of 25:1 relative[r] ...

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Impact of Intra- and Interspecies Variation of Occludin on Its Function as Coreceptor for Authentic Hepatitis C Virus Particles

Impact of Intra- and Interspecies Variation of Occludin on Its Function as Coreceptor for Authentic Hepatitis C Virus Particles

... for cell-to-cell spread of ...in cell culture both as cell-free virions and in a direct cell-to-cell manner that does not seem to involve a cell-free virion ...whether ...

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Standardization and a multilaboratory comparison of Neisseria meningitidis serogroup A and C serum bactericidal assays. The Multilaboratory Study Group.

Standardization and a multilaboratory comparison of Neisseria meningitidis serogroup A and C serum bactericidal assays. The Multilaboratory Study Group.

... buffer, target strains, growth of target cells, target cell number, complement source and concentration, and methods for growth of surviving bacteria) which may affect the reproducibility of ...

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Determination of Infectious Retrovirus Concentration from Colony-Forming Assay with Quantitative Analysis

Determination of Infectious Retrovirus Concentration from Colony-Forming Assay with Quantitative Analysis

... with target cell type and number, transduction time, and concentration of polycation ...encounter target cells due to Brownian motion, their short half-lives, and the requirement for target ...

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Herpesvirus saimiri MicroRNAs Preferentially Target Host Cell Cycle Regulators

Herpesvirus saimiri MicroRNAs Preferentially Target Host Cell Cycle Regulators

... in cell cycle regulation are en- riched among the top miR-HSUR targets ...preferentially target cell cycle regulators. This is consistent with the T-cell oncogenic phenotype of HVS ...this ...

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Cell-to-Cell Transmission Is the Main Mechanism Supporting Bovine Viral Diarrhea Virus Spread in Cell Culture

Cell-to-Cell Transmission Is the Main Mechanism Supporting Bovine Viral Diarrhea Virus Spread in Cell Culture

... of cell-cell contacts, referred to as virological synapses, through the interaction of virus glycoproteins with receptors on the target ...the target cell to establish filopodial bridges ...

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Trans dominant cellular inhibition of DC SIGN mediated HIV 1 transmission

Trans dominant cellular inhibition of DC SIGN mediated HIV 1 transmission

... and target cell interac- tions. To evaluate whether cell contact is required for DMHT, Raji or Raji/DC-SIGN donor cells were preincu- bated with single-round infectious HIV-Luc/ADA, washed, and ...

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Missing the Target?—Targeted Therapy in Small Cell Lung Cancer

Missing the Target?—Targeted Therapy in Small Cell Lung Cancer

... [41] Heist, R.S., Fain, J., Chinnasami, B., Khan, W., Molina, J., Brainerd, V., Leopold, L. and Lynch, T. (2009) A Phase I/II [P1/P2] Study of AT-101 in Combination with Topotecan[t] in Patients with Relapsed or ...

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HSF1 Is Essential for Myeloma Cell Survival and A Promising Therapeutic Target.

HSF1 Is Essential for Myeloma Cell Survival and A Promising Therapeutic Target.

... selective inhibitor of the HSF1 pathway, CCT251236, in human myeloma cell lines, primary 77.. patient myeloma cells and a human myeloma xenograft model.[r] ...

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The spleen may be an important target of stem cell therapy for stroke

The spleen may be an important target of stem cell therapy for stroke

... The CNS regulates immune system activity mainly through complex humoural and neural pathways, in- cluding the hypothalamic-pituitary-adrenal (HPA) axis, vagus nerve (VN) and SNS [169]. Elevated cortisone, corticosterone ...

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Epiregulin as a therapeutic target in non-small-cell lung cancer

Epiregulin as a therapeutic target in non-small-cell lung cancer

... cancer cell; further- more, MEK inhibition downregulated EREG expression, accompanied by downregulation of the ETS1 transcription factor, which binds to the EREG ...

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