TARGETING INFORMATION RESIDES IN THE SIGNAL SEQUENCE
Sequential activation of human signal recognition particle by the ribosome and signal sequence drives efficient protein targeting
... a signal se- quence from the ribosome exit tunnel drives the majority of SRP into the proximal conformation in which SR recruitment can occur rapidly, thus delivering the translating ribosome to the ER ...of ...
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From Sequence to Information
... provide information about interaction between genes or ...two-component signal transduction systems in bacteria is able to recognize and respond to a variety of environmental stim- ...
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Targeting individual cells by barcode in pooled sequence libraries
... single-cell sequence library for reads from individual cells of ...relevant information out of such libraries with reduced sequencing ...lack sequence coverage can be tar- geted for deeper follow-up ...
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Identification of a Type 1 Peroxisomal Targeting Signal in a Viral Protein and Demonstration of Its Targeting to the Organelle
... PTS1 sequence in rotavirus VP4. We identified a tripeptide sequence (CRL) resembling the PTS1 sequence at the C terminus of VP4 of rotavirus strain ...tripeptide sequence at the C termi- ...
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An Endoplasmic Reticulum-Targeting Signal Sequence Enhances the Immunogenicity of an Immunorecessive Simian Virus 40 Large T Antigen Cytotoxic T-Lymphocyte Epitope
... ES sequence. Targeting determinant I and II/III peptides to the ER provided little, if any, enhancement of immunogenicity or antigenicity, suggesting that peptide trans- location into the ER for these ...
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PN Sequence Preestimator Scheme for DS SS Signal Acquisition Using Block Sequence Estimation
... the Division of Information and Communications Engineering, Daejeon University, Daejeon, Korea. Since March 2004, he has been on the faculty of Hanyang University, Seoul, Korea, where he is now an Associate ...
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Identification of a Cytoplasmic Targeting/Retention Signal in a Retroviral Gag Polyprotein
... that is present in type B and D viruses but absent from MuLV were severely impaired for capsid assembly (37). In summary, the data presented here suggest the existence of a novel mechanism by which a cytoplasmic protein ...
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Mapping the Golgi Targeting and Retention Signal of Bunyamwera Virus Glycoproteins
... Golgi targeting and retention signal has previously been shown to reside within the Gn ...Golgi targeting and retention signal of BUN glycoproteins resides in the TMD of the Gn ...
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Thylakoid Protein Targeting/Insertion by a Signal Recognition Particle in Chloroplasts
... of information provides an insight into the new types of interactions which may take place in this overall unique system of protein targeting especially in the transit complex formation step in the ...
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The N terminus of survivin is a mitochondrial targeting sequence and Src regulator
... Survivin 1–10 is a MTS By fusing the first 30 nucleotides of the human survivin gene to GFP cDNA we engineered MGAPTLPPAW – GFP. When expressed in HeLa cells we discovered that it localised to mitochondria (Fig. 2A). To ...
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Post Translational Membrane Protein Targeting by the Chloroplast Signal Recognition Particle
... this information, we estimated the CMC values for aggregate formation by LHCP and a number of LHCP variants as the X-intercepts from linear fits to data (Figure ...
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Structural Analysis of Hepatitis C Virus Core-E1 Signal Peptide and Requirements for Cleavage of the Genotype 3a Signal Sequence by Signal Peptide Peptidase
... core-E1 signal peptide is mainly a hydrophobic segment, which directs the nascent HCV polyprotein to the ER ...This signal sequence presumably plays a key part in arresting translation by host cell ...
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Signal sequence analysis of expressed sequence tags from the nematode Nippostrongylus brasiliensisand the evolution of secreted proteins in parasites
... that signal sequences reflect secretion into the parasite ...which signal-peptide-bearing proteins are truly exported by these multicellular organisms will be clarified by current proteomic analyses on ...
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Phoneme Sequence Modeling in the Context of Speech Signal Recognition in Language “Baoule”
... The speech signal is a complex form drowned in the noise. Its learning is part of complex intelligent activity [10]. By learning a starting model, we will build gradually an effective model for each of the ...
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Characterization of the signal sequence binding domain of Ffh by genetics and comparative analysis
... strain information based upon basic or advanced search parameters, ...strain information, ...v.) sequence similarity searches using BLAST, ...
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Application of an E. coli signal sequence as a versatile inclusion body tag
... Periplasmic expression has shown to be an effective strategy to produce eukaryotic proteins in E. coli. Ini- tially, we aimed to identify the most effective strategy to mediate the periplasmic localization of the ...
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Identification of a Membrane Targeting and Degradation Signal in the p42 Protein of Influenza C Virus
... the signal peptidase consensus sequence is not required for degradation, as p31 expressed alone or p31 expressed from the seg 6 ORF cDNA were degraded with nearly identical ...17-residue sequence ...
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Therapeutic targeting of the MEK/MAPK signal transduction module in acute myeloid leukemia
... Based on its ability to lower the apoptotic threshold, disruption of the MEK/MAPK module has been pro- posed as a novel approach to the chemosensitization of cancer cells (36). Although our findings support this concept, ...
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Sequence Information. Sequence information. Good web sites. Sequence information. Sequence. Sequence
... Linköping University & Karolinska Institutet 2 Sequence information Sequence Comparisons Pair-wise Multiple Database searches SRS Entrez Protein families Patterns Post-translational [r] ...
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Advances in Targeting Signal Transduction Pathways.
... Advances in Targeting the NF-kappaB Pathway. Targeting the NF-kappaB pathway has been shown to be a potential therapeutic approach in leukemia and other therapies. The NF-kappaB pathway is regulated in part ...
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