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TARGETS FOR THE PRIORITISATION, INVESTIGATION AND

Interactive online application for the prediction, ranking and prioritisation of drug targets in Schistosoma haematobium

Interactive online application for the prediction, ranking and prioritisation of drug targets in Schistosoma haematobium

... the prioritisation strategy applied here had a substantial ef- fect on the score distribution (Table 1 and ...drug targets between the present and earlier ...

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Investigation of mitochondrial targets for cardioprotection

Investigation of mitochondrial targets for cardioprotection

... An important consideration for the suitability of the model of ischaemia-reperfusion presented here is the invasive nature of the surgical protocol concerning: (1) open-chest preparation of the animal and (2) direct ...

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Investigation of JAK2 targets in haematological malignancy

Investigation of JAK2 targets in haematological malignancy

... Our data shows it is clear that combining JAK2 inhibition with disruption of PML leads to a significant increase in apoptosis of JAK2 V617F containing cell lines, although t[r] ...

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Investigation of novel PKC targets in the regulation of autophagy

Investigation of novel PKC targets in the regulation of autophagy

... 22 4.2. Decipher Lentiviral shRNA library Transduction DECIPHER lentiviral shRNA library, Mouse Module 1: Pathway Targets comprises 27,000 shRNAs targeting 5,000 gene sequences and carries a puromycin-resistance ...

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A Numerical Investigation of Blast Loading and Clearing on Small Targets

A Numerical Investigation of Blast Loading and Clearing on Small Targets

... larger targets whose loading is dominated by the diffraction phase and demonstrated excellent correlation with experimental ...small targets, Hudson [11] observed that ‘as an approximation, we may write ...

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Automatically Creating Realistic Targets for Digital Forensics Investigation

Automatically Creating Realistic Targets for Digital Forensics Investigation

... potentially around-the-clock access to these facilities. In this paper, we discuss FALCON (Framework for Laboratory Exercises Con- ducted Over Networks), our architecture for the automatic creation, deployment, and ...

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Investigation into the effects of project delivery methods on LEED targets

Investigation into the effects of project delivery methods on LEED targets

... All of the case studies either achieved or exceeded their LEED target and seven achieved their schedule and budget goals due to the IPD process. There were five projects that were able to exceed the LEED target. Out of ...

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Qualitative investigation of targets for and barriers to interventions to prevent psychosis relapse

Qualitative investigation of targets for and barriers to interventions to prevent psychosis relapse

... retrospective investigation. Fourthly, further investigation of the help seeking process in re- lapse is warranted, for example regarding the role of at- tachment style, and service related barriers to help ...

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Investigation of oxygen targets and hypoxic adaptation in paediatric critical illness

Investigation of oxygen targets and hypoxic adaptation in paediatric critical illness

... reported prescribing oxygen saturation targets. Clinicians working in a regional centre were less concerned with oxygen toxicity. Further, only 26.5% of the re- spondents considered oxygen related lung injury to ...

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Functional investigation of prognostic biomarkers and therapeutic targets in glioma brain tumors

Functional investigation of prognostic biomarkers and therapeutic targets in glioma brain tumors

... Further investigation revealed an increase in the percentage of cells in S- phase corresponding to Rapamycin and Actinomycin D co-treatment compared with Actinomycin D treatment alone, whereas no major difference ...

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TITLE: Amplified Genes in Breast Cancer: Molecular Targets for Investigation and Therapy

TITLE: Amplified Genes in Breast Cancer: Molecular Targets for Investigation and Therapy

... The following experiments were performed to distinguish among these alternatives First, we studied when micronuclei are generated during the cell cycle of Colo320 DM cells The cells we[r] ...

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Passenger Management by Prioritisation

Passenger Management by Prioritisation

... through prioritisation was not sufficient to balance the disadvantages which ...direct prioritisation of such a group on the other hand led directly to an improvement in their boarding ...appropriate ...

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Prioritisation of Network Security Services

Prioritisation of Network Security Services

... simple prioritisation strategy and highlights its limitations, section 3 details how connectivity in modern IT networks has evolved and how this has impacted the security risks, resulting in our ...

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Self-prioritisation in social cognition

Self-prioritisation in social cognition

... Sorensen, 1999; A. R. Conway et al., 2001; Wood & Cowan, 1995). For example, own- name stimuli have been found to survive the “attentional blink” (Shapiro, Caldwell, & Sorensen, 1997). The attentional blink ...

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Incorporating seascape connectivity in conservation prioritisation

Incorporating seascape connectivity in conservation prioritisation

... Representation targets for individual habitats similarly preference larger contiguous habitat patches, an effect further augmented by the use of Marxan’s BLM, which acts to priori- tise areas in which contiguous ...

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Report of the Research Prioritisation Steering Group

Report of the Research Prioritisation Steering Group

... ambitious targets of generating 40 per cent of electricity from renewables by 2020, including 500 MW from ocean energy, which will be vital to ensuring that we meet our greenhouse gas emissions targets by ...

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Risk analysis and prioritisation

Risk analysis and prioritisation

... a prioritisation exercise while the second is a more detailed risk assessment which is intended for the purpose of supporting legislative developments and also allowing policy makers to gather more information if ...

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Bridge approach guardrail prioritisation

Bridge approach guardrail prioritisation

... 6.2.1 Identification of Site The starting point of the prioritisation procedure is to determine which bridge approach guardrail sites are going to be included in the prioritisation. Each of these bridge ...

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Vaccine Research Question Prioritisation

Vaccine Research Question Prioritisation

... • Research into communities that have been disproportionately impacted and that have still not been factored into the prioritisation of the vaccination order, e.g. BAME communities. It would be interesting to see ...

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ADVICE NOTE: PRIORITISATION FOR DESTINATION MANAGEMENT PLANS. Advice note: Prioritisation for Destination Management Plans

ADVICE NOTE: PRIORITISATION FOR DESTINATION MANAGEMENT PLANS. Advice note: Prioritisation for Destination Management Plans

... of prioritisation varying in complexity; however for the purposes of a DMP the simplest and most useful is outlined in the diagram below: One of the most straightforward methods of prioritisation is through ...

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