TCF-4
<p>TCF-4 Regulated lncRNA-XIST Promotes M2 Polarization Of Macrophages And Is Associated With Lung Cancer</p>
... Recently, TCF-4 was reported to elevate with devel- opment of lung cancer, and inhibition of TCF-4 could suppress lung cancer cells proliferation, invasion growth both in vitro and in vivo, ...
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KIF23 is an independent prognostic biomarker in glioma, transcriptionally regulated by TCF-4
... Kinesin family member 23 (KIF23), a nuclear protein and a key regulator of cellular cytokinesis, has been found to be overexpressed as an oncogene in glioma. However, the prognostic and clinicopathological features of ...
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KIFC1 is activated by TCF-4 and promotes hepatocellular carcinoma pathogenesis by regulating HMGA1 transcriptional activity
... The KIFC1 promoter sequence was cloned into the pGL3-Basic plasmid. The Super TOPflash luciferase re- porter vector served as a positive control of Wnt/β-ca- tenin pathway activation. Renilla activities were analyzed ...
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Gastrin is a target of the β catenin/TCF 4 growth signaling pathway in a model of intestinal polyposis
... dominant-negative TCF-4 expres- sion ...potential TCF-binding site –103 CCCATTCCT ...wild-type TCF- 4–binding site found on the human gastrin promoter from –103 to –90, a mutated ...
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Evidence for Regulation of Long Terminal Repeat Transcription by Wnt Transcription Factor TCF-4 in Human Astrocytic Cells
... of TCF-4 is not restricted to lym- phoid tissue, and several studies suggested its involvement in a variety of developmental processes, including neurogenesis ...and TCF-4, in human astrocytic ...
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Identification of Novel T Cell Factor 4 (TCF-4) Binding Sites on the HIV Long Terminal Repeat Which Associate with TCF-4, β-Catenin, and SMAR1 To Repress HIV Transcription
... between TCF-4 binding to the HIV LTR and association with the nuclear ...143 TCF-4 binding site diminished SMAR1 binding to the LTR by approximately 50% ...whether TCF-4 directly ...
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Roles of β-catenin, TCF-4, and survivin in nasopharyngeal carcinoma: correlation with clinicopathological features and prognostic significance
... β‑catenin, TCF‑4, and ...β‑catenin, TCF‑4, and ...β‑catenin, TCF‑4, and survivin was higher in NPC tissues than in CNP ...β‑catenin, TCF‑4, and survivin were ...
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Human Immunodeficiency Virus-Restricted Replication in Astrocytes and the Ability of Gamma Interferon To Modulate This Restriction Are Regulated by a Downstream Effector of the Wnt Signaling Pathway
... expression. TCF-4 inhibition abrogates restriction of HIV replication in untreated/ non-IFN- ␥ -primed ...the TCF-4 dominant-negative (DN) mutant or GFP construct, keeping the DNA amount ...
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Novel naphthoquinone analogs that target Wnt/β Catenin/TCF4 signaling pathway and clonogenic activity of colon carcinoma cells
... al., 2013; Lepourcelet et al., 2004; Wei et al., 2010; Handeli et al., 2008; Saraswati et al., 2010; Watanabe et al., 2011; Lepourcelet et al., 2004; Barker and Clevers, 2006; Lu et al., 2004) Most of these compounds are ...
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Original Article miR-140-5p inhibits proliferation, invasion, and promote apoptosis of non-small cell lung cancer cells through targeted inhibition of Wnt signaling pathway
... β-catenin, TCF-4, PCNA, E-cadherin, N-cadherin, Bcl-2 and Bax in each group were detected using quantitative real-time PCR (qRT-PCR) and Western ...β-catenin, TCF-4, PCNA, N-cadherin and Bcl-2 ...
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miR 34a Inhibitor May Effectively Protect against Sevoflurane Induced Hippocampal Apoptosis through the Wnt/β Catenin Pathway by Targeting Wnt1
... of TCF-4, Cyclin D1, β-catenin, and Wnt1 in hippocampal neurons exposed to sevoflurane, while anti-miR-34a exerted the reverse effects, suggesting that miR-34a inhibitor activates the Wnt/β-catenin pathway ...
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Role of β-Catenin and TCF/LEF Family Members in Transcriptional Activity of HIV in Astrocytes
... ticated assessment of HIV infection in astrocytes demonstrated a considerable level of HIV Env in astrocytes from HAD patients and up to 3% in the absence of HAND (10), which is similar to the size of the HIV pool in the ...
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Active β-Catenin Signaling Is an Inhibitory Pathway for Human Immunodeficiency Virus Replication in Peripheral Blood Mononuclear Cells
... of TCF (13, 17). TOPflash is a TCF reporter plasmid containing two sets of three copies of wild-type TCF binding sites driven by the thymidine kinase minimal prompter and upstream of a luciferase ...
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Original Article Expression of β-catenin and axin in metaplastic breast carcinomas
... β-catenin, Tcf-4 and Axin protein are key molecules in wnt signaling ...β-catenin, Tcf-4 and Axin proteins were examined in 40 MBC tissues and 43 invasive ductal carcinoma (IDC) tissues with ...
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ROLE OF GSTP, TCF, ELMO1, TRPC1, IL-10 GENE POLYMORPHISM IN DIABETIC NEPHROPATHY
... The GSTs are a multigenic super family of detoxification enzymes that are important for cell protection against oxidative break, as well as the biotransformation of xenobiotics, due to their acting on a wide variety of ...
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Examination of effects of GSK3β phosphorylation, β-catenin phosphorylation, and β-catenin degradation on kinetics of Wnt signaling pathway using computational method
... Recent advances have further illustrate how phosphoryla- tion and dephosphorylation of major components in the wnt pathway affect the stability of β-catenin and its TCF transcription activity [3-7]. It has been ...
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Biomimetic TCF Bleaching of Pulp by Simple Inorganic Complexes of Cupric/Cobalt Acetate
... to increase the reactive efficiency of peroxide. For examples, high temperature is usually necessary to obtain high reactive ability of bleaching agents. However, under alkaline conditions, high temperature accelerates ...
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Acceptability of a moringa-added complementary soft porridge to caregivers in Hammanskraal, Gauteng province and Lebowakgomo, Limpopo province, South Africa
... Results: Sensory evaluation results showed that the acceptability of the two traditional complementary foods decreased as the level of moringa leaf powder increased. Caregivers indicated in the focus-group discussions ...
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Totally chlorine-free bleaching of prehydrolysis soda pulp from plantation hardwoods consisting of various lignin structures
... During the prehydrolysis, hemicelluloses and other organics are dissolved in the prehydrolysate (PHL). The major reactions include depolymerization and disso- lution of hemicellulose [4, 7], along with further ...
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Complex modulation of androgen responsive gene expression by methoxyacetic acid
... Array 4, testosterone + MAA ...and 4 (effects of testoster- one in the absence and presence of MAA, respectively), and, to a lesser extent, between arrays 2 and 3 (effects of MAA in the absence and presence ...
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