telomerase activity
Telomerase activity in human pleural mesothelioma
... minutes telomerase products were amplified using TS and ACX primers (35 cycles at 94°C for 30 s, 53°C for 30 s, and 72°C for 30 ...(Bio-Rad). Telomerase activity was graded as negative (6 bp ladder ...
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Case Report Mandibular central leiomyosarcoma with high telomerase activity: a case report
... of telomerase activity, however, this leiomyosarcoma has an abundant telomerase activity, which is one of the marker of cell proliferation (Figure ...
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Withania somnifera Root Extract Enhances Telomerase Activity in the Human HeLa Cell Line
... of telomerase activity in HeLa extracts employed the PCR-based telomeric repeat amplification pro- tocol (TRAP assay) is a modification of the assay described by ...
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Presence of Telomerase Activity with Undetectable P16 Gene Mutation in Malaysian Patients with Brain Tumor
... 1. Telomerase activity in various type of brain tumors is summarized in Table ...Overall, telomerase activity was detected in six cases of these tumors ...between telomerase ...
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Unusually stable abnormal karyotype in a highly aggressive melanoma negative for telomerase activity
... of telomerase in normal fibroblasts has been connected to karyotypic sta- bility ...test telomerase activity in cultured cells from 2 sub-cultures from both peritoneal ...
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Cascaded Electrochemiluminescence Signal Amplifier for the Detection of Telomerase Activity from Tumor Cells and Tissues
... of telomerase in 1985, various methods have been developed to evaluate telomerase activity ...measure telomerase activity. This technique can detect telomerase activity in ...
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Signaling through estrogen receptors modulates telomerase activity in human prostate cancer
... measure telomerase activity and telomere length in this group of tumors, since persistence of ER- β expression and subsequent telomerase induction may contribute to extending cell life span, thus ...
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KLF4 downregulates hTERT expression and telomerase activity to inhibit lung carcinoma growth
... and telomerase activity in lung cancer cell lines and a mouse ...promoter activity in cells infected with Ad-KLF4, and chromatin immunoprecipitation analysis demonstrated that endogenous KLF4 ...
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Poly (ADP-ribose) polymerase 3 (PARP3), a potential repressor of telomerase activity
... Our results suggest that the role of PARP3 in main- taining telomere integrity could be performed though regulation of telomerase activity. Therefore, depletion of PARP3 expression could result in a ...
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Glucose restriction decreases telomerase activity and enhances its inhibitor response on breast cancer cells: possible extra-telomerase role of BIBR 1532
... immortalization, telomerase has become an attractive target for selective cancer ther- ...the activity of ...of telomerase, immunotherapy using hTERT as a tumor- associated antigen, and gene therapy ...
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Fibroblast growth factor receptor 3 effects on proliferation and telomerase activity in sheep growth plate chondrocytes
... The purpose of the present study was to experimentally evaluate effects of altered FGFR3 expression on prolif- eration and telomerase activity in sheep growth plate chondrocytes. Wild type growth plate ...
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Telomere length and telomerase activity in non-small cell lung cancer prognosis: clinical usefulness of a specific telomere status
... An altered telomere length in cancer cells could give the ability to metastasize and cause recurrent disease and, in consequence, be a predictor of clinical outcome. Previous works concluded that careful assessment of ...
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NFX1-123 Increases hTERT Expression and Telomerase Activity Posttranscriptionally in Human Papillomavirus Type 16 E6 Keratinocytes
... and telomerase activity in vivo, we hypothesized that these regions would be necessary for the posttranscriptional activity of ...and telomerase activity in ...in telomerase ...
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The effect of high intensity interval training on telomere length and telomerase activity in non-athlete young men
... Materials and methods: 30 inactive students were selected as sample and randomly divided into two groups of exercise (15 people) and control (15 people) in this semi-experimental study. The exercise group performed 8 ...
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The antiretroviral agent saquinavir enhances hTERT expression and telomerase activity in human T leukaemia cells in vitro
... Telomerase activity was determined according to the telo- meric repeat amplification protocol ...ase activity was assayed in whole cell ...of telomerase activity were collected at the ...
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Effect of aromatase inhibitor (fadrozole) on proliferation, estradiol production and telomerase activity in pig granulosa cells in vitro
... The proliferative potential of small-follicle GC was significantly higher (P < 0.01) under all culture condi- tions. Estradiol production was suppressed (P < 0.01) in both granulosa cell populations cultured in the ...
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HIV-1 Induces Telomerase Activity in Monocyte-Derived Macrophages, Possibly Safeguarding One of Its Reservoirs
... FIG 3 (A) MDM were infected with different HIV strains (93BR020, HXB2, JRCSF, SF162, and IIIB), and after 12 days telomerase activity was studied by quantitative real-time PCR. MDM infected with SF162 and ...
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Significance of Telomerase Activity and Gene Expression in Colorectal Cancer
... study telomerase activity was found to have a tendency to be higher in tumor tissues compared to corresponding normal ...higher telomerase activity compared to early stage ...between ...
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Comparison of Telomerase Activity in Malignant and Benign Pleural Effusions
... of telomerase activity in the malignant bronchoalveolar lavages and pleural effusions were ...of telomerase activity to be above 80% ...of telomerase activity was similar to ...
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Telomerase activity is required for bleomycin induced pulmonary fibrosis in mice
... for telomerase activity includes a reverse transcriptase that adds on telomeric repeats at the end of chromosomes using an RNA ...This telomerase core enzyme consists of the telomerase RNA ...
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