Th17/Treg imbalance
Variation of Peripheral Th17/Treg Imbalance in Patients with Idiopathic Membranous Nephropathy After Cyclosporin a Treatment: A Prognostic Marker of Idiopathic Membranous Nephropathy
... controls, Th17%, levels of IL-17 and TNF-α were up-regulated, whereas Treg% and TGF-β level were down-regulated in the peripheral blood of IMN ...This imbalance was more pronounced in the high-risk ...
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Original Article Peripheral Th17/Treg imbalance in patients with atherosclerotic cerebral infarction
... of Treg cells ...of Treg cells, and positively cor- related with the frequency of Th17 ...Moreover, Treg and Th17 cells from ACI patients were more susceptible to the influence of ox- ...
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Valproic acid ameliorates coxsackievirus B3 induced viral myocarditis by modulating Th17/Treg imbalance
... Histone deacetylases (HDACs) are part of a vast family of enzymes involved in chromatin remodeling that play a key role in the differentiation and immune function of T cells [10, 11]. Inhibition of HDAC activ- ity is ...
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Original Article Regulatory function of TH17/Treg ratios in the children suffering from adenoidal hypertrophy with complications
... the Th17/Treg ratios in both peripheral blood and local adenoid tissues were higher in the children suffering from AH complicated with OME, which means decreased Treg cells com- pared to the ...
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The ratio of Th17/Treg cells as a risk indicator in early acute respiratory distress syndrome
... between Th17 and Treg cells has been suggested as a new paradigm for a number of different inflammation and autoimmune diseases ...in Th17 and Treg cells, we used Th17/Treg to ...
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Original Article Distinct different sensitivity of Treg and Th17 cells to Fas-mediated apoptosis signaling in patients with acute coronary syndrome
... of Th17/Treg imbalance in ACS patients are still ...of Th17 and Tregs to Fas-mediated apoptosis which could lead to Th17/Treg imbalance in ACS ...of Th17 and ...
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Original Article Imbalance of Th1/Th2 and Th17/Treg promoting schistosome egg granuloma formation
... hand, Th17 and Treg cells have many obviously difference in differentia- tion and regulation ...mechanism. Th17 cells are derived from the naive Th cells induced by low concentrations of TGF-β and ...
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Ginkgo biloba extract attenuates the disruption of pro-and anti-inflammatory T-cell balance in peripheral blood of arsenicosis patients
... the Th17/Treg balance was abnormal in peripheral blood mononuclear cells (PBMCs) of patients with arsenicosis caused by burning ...the Th17/Treg imbalance in patients with ...of ...
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<p>Changes and Clinical Significance of Detailed Peripheral Lymphocyte Subsets in Evaluating the Immunity for Cancer Patients</p>
... individuals, Treg cells played an important role in the maintenance of ...increased Treg cells in various tumors have been ...of Treg/Th17 was closely related to immunity and immune ...The ...
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Imbalance of Th17/Treg in the Pathogenesis of Mice with Paraquat-induced Acute Lung Injury
... the imbalance of Th17/Treg cells may be involved in the pathogenesis of ...of Th17 cells and lower expression of CD4+CD25+Treg cells has been shown in the poisoned group compared with ...
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Original Article Metformin regulates Th17/Treg cell balance and reduces hyperplastic synovium via activating AMPK and inhibiting mTOR in a collagen-induced arthritis rat model
... by Th17, has synergistic effects with tumor necrosis factor- (TNF-)α, IL-1β and IL-6 in cases of RA ...understood. Th17 and Treg cells often act with each other, and ...
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The Toll-like Receptor 2 (TLR2)-related Immunopathological Responses in the Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis
... In MS and EAE, the rupture of the blood-brain barrier (BBB) and migration of activated leukocytes occur into the CNS. 11 The DCs migrate across the inflamed BBB and trigger the differentiation of myelin specific naïve ...
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Differential regulation of human Treg and Th17 cells by fatty acid synthesis and glycolysis
... activated Treg cells utilize both glycolysis and oxidative phosphorylation to a greater extent than activated Tconv ...of Treg or Tconv, we also performed Seahorse analysis on freshly sorted Treg and ...
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Research Progress of Th17/Treg Cells and Their Transcription Factors in Autoimmune Diseases
... of Th17 in IBD remains controversial. Some believe that Th17 cells can mediate intestinal inflammation by releasing inflammatory factors, while others believe that Th17 cells have a protective effect ...
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Deletion of Smad3 improves cardiac allograft rejection in mice
... and Treg cells et al [34], It is highly possible that inhibition of IL-10 expression in Smad3 KO mice during cardiac allograft rejection may be associated with inhibition of macrophage infiltration and importantly ...
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Sirtinol regulates the balance of Th17/Treg to prevent allograft rejection
... of Treg cells and allograft survival in tissues such as the lung, kidney and liver ...low Treg cell counts ...the Th17/Treg balance, has outstanding potential as an immunosuppressive ...
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Mdivi-1, a mitochondrial fission inhibitor, modulates T helper cells and suppresses the development of experimental autoimmune encephalomyelitis
... The proper functioning of mitochondria in T cells is crit- ical for their activation, differentiation, and function [19]. T cell plasticity is influenced by their metabolism and ATP demand, where mitochondrial morphology ...
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Imbalance of Th17 Cells and Regulatory T Cells in Tuberculous Pleural Effusion
... As shown in Fig. 4C, CFSE ⫹ CD4 ⫹ T cells were gated to exclude CD39 ⫹ Tregs, and expression of IL-17 was examined. We noted that substantial amounts of Th17 cells could be FIG. 4. Latency-associated peptide (LAP) ...
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Treg/Th17 imbalance and its clinical significance in patients with hepatitis B-associated liver cirrhosis
... Tregs, Th17 cells mediate inflammatory responses and play an important role in autoimmune diseases, tumors, and infectious ...diseases. Th17 cells secrete a variety of cytokines, the main of which are ...
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The changes and its significance of Th17 and Treg cells and related cytokines in patients with tuberculosis pleurisy
... of Treg cells ...and Th17 cells, but no significant correlation between IL-6 levels and Treg ...and Treg cells in peripheral ...from Treg cells. Research showed that IL-6 was a key ...
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