Th1, T helper 1 cells
The role of follicular helper CD4 T cells in the development of HIV 1 specific broadly neutralizing antibody responses
... are cells that localize to the lymph nodes, within well-defined structures called B-cell follicles ...(Fig. 1) [20, ...B cells as well as for the survival of memory B cells and antibody- ...
10
Frequencies of Circulating Th1-Biased T Follicular Helper Cells in Acute HIV-1 Infection Correlate with the Development of HIV-Specific Antibody Responses and Lower Set Point Viral Load
... mononuclear cells (PBMCs) were thawed, rested, and stained using a LIVE/DEAD Aqua dead cell staining kit (Thermo Fisher Scientific, Waltham MA, USA) per the manufacturer’s instructions, followed by staining with an ...
15
<em>Chlamydia trachomatis</em> recombinant MOMP encapsulated in PLGA nanoparticles triggers primarily T helper 1 cellular and antibody immune responses in mice: a desirable candidate nanovaccine
... potentiates T helper 1 (Th1) immune responses induced by a peptide derived from the recombinant major outer membrane protein (rMOMP) of Chlamydia trachomatis, and may be a promising vaccine ...
15
Local Expression of T Cell Subsets in Sensitized and Unsensitized Experimental Cystic Echinococcosis.
... immune cells and their contributions to ...of T cell subsets, T-helper 1 (Th1), T-helper 2(Th2), T regulatory ...and T cytotoxic (CD8) in sensitized ...
11
A multidrug resistance protein (MRP) like transmembrane pump is highly expressed by resting murine T helper (Th) 2, but not Th1 cells, and is induced to equal expression levels in Th1 and Th2 cells after antigenic stimulation in vivo
... CD4 1 T cell subset within LN of ...CD4 1 T ...gen-triggered T cells in situations of infectious diseases or in autoimmune diseases where the causing antigen is unknown and ...
9
Decreased T helper 17 cells in tuberculosis is associated with increased percentages of programmed death ligand 1, T helper 2 and regulatory T cells
... of Th1, Th2 and Th17 cells were lower in the patients with extra-pulmonary TB compared to those with pul- monary TB ...of Th1 cells in extra-pulmonary TB is not consistent with previous ...
8
Mesenchymal stem cells: a promising way in therapies of graft-versus-host disease
... stem cells; EVs: Extracellular vesicles; Th1: T helper cells 1; aGVHD: Acute graft-versus-host disease; Th2: T helper cells 2; APC: Antigen presenting ...
11
Cellular Immune Responses to Recombinant Mycobacterium bovis BCG Constructs Expressing Major Antigens of Region of Difference 1 of Mycobacterium tuberculosis
... difference 1 (RD1), such as pe35, cfp10, and ...selected T helper 1 [Th1], Th2, and anti-inflammatory cytokines, ...spleen cells from mice immunized with native BCGs and rBCGs ...
8
A melanoma helper peptide vaccine increases Th1 cytokine production by leukocytes in peripheral blood and immunized lymph nodes
... proliferating cells was determined on peptide-stimulated CFSE-labeled PBMC after phorbol 12-myristate 13-acetate (PMA; 40 ng/ml; Sigma-Aldrich) plus ionomycin (1 μM; ...dividing cells. For flow ...
11
Interleukin-22 Promotes T Helper 1 (Th1)/Th17 Immunity in Chlamydial Lung Infection
... Th17 cells, and there are data to sug- gest that IL-17 and IL-22 can cooperate in host defense against extracellular bacterial ...of Th1 and Th17 cell ...of T-cell ...
11
Imbalanced shift of cytokine expression between T helper 1 and T helper 2 (Th1/Th2) in intestinal mucosa of patients with post-infectious irritable bowel syndrome
... inflammatory cells, proinflammatory fac- tors, and immunological activation in the intestinal mu- cosa of PI-IBS patients ...immunological cells’ contact with certain foods and microorganisms would easily ...
6
Treatment with depleting CD4 monoclonal antibody results in a preferential loss of circulating naive T cells but does not affect IFN gamma secreting TH1 cells in humans
... ducing T helper 2 (TH2)-type cells in the anti-CD4 treated group was observed, numbers of IFN- g –producing T helper 1 (TH1)-type cells remained stable, resulting ...
8
Plasma levels of monokine induced by interferon-gamma/chemokine (C-X-X motif) ligand 9, thymus and activation-regulated chemokine/chemokine (C-C motif) ligand 17 in children with Kawasaki disease
... blood cells (WBC), C-reactive protein (CRP) and erythrocyte sedimentation rate ...(ESR). T cells activation has been reported to be participated in the immunological pathogenesis [3, 4], and some ...
6
Autophagy enhances mesenchymal stem cell-mediated CD4+ T cell migration and differentiation through CXCL8 and TGF-β1
... + T cells ...recruit T leukomonocytes, monocytes, ...+ T cells, as they are critical effectors of the immune adaptive response ...+ T cells can prolifer- ate and ...
13
Novel Role of CD8+ T Cells and Major Histocompatibility Complex Class I Genes in the Generation of Protective CD4+ Th1 Responses during Retrovirus Infection in Mice
... FV-erythroleukemia cells grown in the Cellmax artificial capillary cell culture system in Cellulosic MPS cartridges with a molecular mass cutoff of 30 kDa (Spectrum, Laguna Hills, ...AA41 cells were grown ...
7
Enhanced IgG4 production by follicular helper 2 T cells and the involvement of follicular helper 1 T cells in the pathogenesis of IgG4 related disease
... Tfh cells were defined as CD3 + CD4 + CD45RA - CXCR5 + cells, and Tfh1, Tfh2, or Tfh17 cell subsets as CXCR3 + CCR6 - cells, CXCR3 - CCR6 - cells, or CXCR3 - CCR6 + cells among Tfh ...
14
Immune contexture defined by single cell technology for prognosis prediction and immunotherapy guidance in cancer
... tumor, T cell activation was a continuous process. They found that B cells were enriched in lymph nodes, while naive T cells were concentrated in peripheral ...toxic T cells, ...
9
Interferon-γ promotes gastric lymphoid follicle formation but not gastritis in Helicobacter-infected BALB/c mice
... Formalin-fixed gastric tissue segments were stained with Harris’ Hematoxylin and Eosin or Giemsa and then assessed blind for histopathological changes [28] and Helicobacter felis colonisation levels [29], respectively. ...
9
The pro-inflammatory potential of T cells in juvenile-onset systemic lupus erythematosus
... + T cells are known to regulate B cell autoantibody production through provision of co- stimulatory signals and cytokines ...individual T cell subsets in JSLE whilst central to dis- ease progression ...
6
Helper T cells in flavivirus infection
... Recently the YF, West Nile dengue type 2 al., DEN2 encephalitis of yellow fever Rice et amino {SLE and virus genomes have been investigated 1985, 1986; Dalgarno et al., 1986a; amino-term[r] ...
238