Th17/Treg balance
Pioglitazone stabilizes atherosclerotic plaque by regulating the Th17/Treg balance in AMPK-dependent mechanisms
... Previous studies have established the upstream signal- ing of AMPK [40]: liver-kinase B1(LKB1) and Ca(2+)/ calmodulin-dependent kinase kinase 2 (CaMKKβ), which induce phosphorylation at threonine (Thr-172) and acti- vate ...
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Vasoactive intestinal peptide ameliorates renal injury in a pristane-induced lupus mouse model by modulating Th17/Treg balance
... immune balance [10, ...of Treg subpopulations while decreasing the number of Th17 subpopulations to improve inflammation in asthmatic mice by regulating Th17/Treg balance and VIP ...
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Original Article Influence of Th17/Treg balance on progression of liver cirrhosis in patients with chronic hepatitis B
... (Th17/Treg) balance on progression of liver cirrhosis in patients with chronic hepatitis B ...of Th17 and Treg cells in peripheral blood ...calculated Th17/Treg ...between ...
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The Th17/Treg balance and the expression of related cytokines in Uygur cervical cancer patients
... that Th17 cells and Treg cells were closely related with malignant tumors such as gastric cancer, ovarian cancer and colon cancer ...of Th17 cells in the UCC group ...of Th17 cells in- creased ...
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Pingchuan formula improves asthma via restoration of the Th17/Treg balance in a mouse model
... regulates Treg/Th17 cells and their as- sociated ...the balance of Treg/ Th17 in an ovalbumin (OVA)-induced asthma mice model with dexamethasone (DEX) as a positive ...
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Overexpression of TGFβ1 in murine mesenchymal stem cells improves lung inflammation by impacting the Th17/Treg balance in LPS-induced ARDS mice
... of Th17/Treg, which is regulated by antigen-stimulated costimulatory molecules, antigen- presenting cells, cytokines, and intracellular signals ...of Th17/Treg [12], is expressed at low levels ...
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Original Article The scutellaria baicalensis stem-leaf total flavonoid regulates the balance of Th17/Treg in EAE rats
... whereas Treg cells play a pivotal role in maintaining the immune tolerance and immune ...that Th17 cells secrete pro-inflam- matory cytokine interleukin (IL)-17 [8, 9], Treg cells secrete soluble ...
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Alteration of Th17 and Treg cells in patients with unexplained recurrent spontaneous abortion before and after lymphocyte immunization therapy
... the Th17⁄Treg balance has challenged the conventional para- digm of Th1⁄Th2 hypothesis ...[4,5]. Th17 and Treg T cells have been described as two subsets that are distinct from Th1 and ...
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Original Article Distinct different sensitivity of Treg and Th17 cells to Fas-mediated apoptosis signaling in patients with acute coronary syndrome
... to Treg apopto- sis, but also suggested that targeting Treg apoptosis may be a therapeutic strategy to maintain Th17/Treg balance in ACS, further leading to plaque ...inhibiting ...
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Ginkgo biloba extract attenuates the disruption of pro-and anti-inflammatory T-cell balance in peripheral blood of arsenicosis patients
... the Th17/Treg balance was abnormal in peripheral blood mononuclear cells (PBMCs) of patients with arsenicosis caused by burning ...the Th17/Treg imbalance in patients with ...of ...
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Sirtinol regulates the balance of Th17/Treg to prevent allograft rejection
... of Treg cells and allograft survival in tissues such as the lung, kidney and liver ...low Treg cell counts ...the Th17/Treg balance, has outstanding potential as an immunosuppressive ...
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Original Article Th17/Treg cell imbalance in patients with early esophageal squamous cell carcinoma
... of Th17 and Treg cells in normal controls is balanced, and this balance is broken in patients with early ...of Th17 and Treg cells in the peripheral blood and their tissue expression ...
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Mesenchymal stem cells regulate the Th17/Treg cell balance partly through hepatocyte growth factor in vitro
... of Th17 cells to exert anti-inflammatory effects through the induction of a regulatory T cell phenotype in these cells ...the Th17/Treg cell ...differentiated Th17 cells and Treg cells ...
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Amelioration of autoimmune arthritis by adoptive transfer of Foxp3 expressing regulatory B cells is associated with the Treg/Th17 cell balance
... transfected with Foxp3 were transferred to DBA/1J mice on days 7 and 28 after the first immunization. Disease progression was monitored. In control mice, clinical dis- ease was apparent on day 21 after the first ...
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T cell unresponsiveness in a pediatric cystic fibrosis patient: a case report
... and Th17 differentiation (Figures 1B, C), but compared to control showed somewhat more Th17 and less Th1, con- sistent with our recent report of an innate predisposition ...
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Original Article Regulatory function of TH17/Treg ratios in the children suffering from adenoidal hypertrophy with complications
... and Th17 ones play a pivotal role in the pathogenesis of allergic rhinitis ...(AR). Th17 and Treg cells showed significant changes in children with ...of Treg cells. Whether the changes of ...
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Deletion of Smad3 improves cardiac allograft rejection in mice
... transplantation tolerance. Smad3 binding to the enhancer of Foxp3 gene is a necessary step in Treg induction [13, 14]. The finding from this study showed that mice lacking Smad3 impaired the Treg cell ...
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Differential regulation of human Treg and Th17 cells by fatty acid synthesis and glycolysis
... differentiated Treg cells demonstrated the highest oxidation of the FA palmitate compared with other effector T cell subsets ...Additionally, Treg cell differentiation was inhibited following treatment with ...
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Research Progress of Th17/Treg Cells and Their Transcription Factors in Autoimmune Diseases
... and Th17-associated cytokines were overexpressed in skin lesions and plasma of patients with psoriasis, which showed an increase in IL-23 and Th17 cells producing ...of Th17 cells and IL-17A ...
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Mdivi-1, a mitochondrial fission inhibitor, modulates T helper cells and suppresses the development of experimental autoimmune encephalomyelitis
... Our results show that Mdivi-1 reduced the number of in- flammatory cells while increasing the number of Treg cells in the CNS of EAE mice. How Mdivi-1 affects Th cell dif- ferentiation in EAE is unknown. Given ...
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