Th2, T helper 2
Imbalanced shift of cytokine expression between T helper 1 and T helper 2 (Th1/Th2) in intestinal mucosa of patients with post-infectious irritable bowel syndrome
... the Th2-derived cytokine IL-10 was significantly lower in the intestinal mucosa of PI-IBS ...while Th2-derived cytokines decreased in PI-IBS patients, which implied that the Th1/Th2 balance was ...
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T-helper 1 versus T-helper 2 lymphocyte immunodysregulation is the central factor in genesis of Burkitt lymphoma: hypothesis
... of T-cell surveil- lance failure; the over-determination and the multifacto- rial infectious aetiology of BL ...a TH2-dominant immune profile serves a duo purpose of propagating B-cell proliferation and ...
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Local Expression of T Cell Subsets in Sensitized and Unsensitized Experimental Cystic Echinococcosis.
... of Th2 cells (Lundi et ...regulatory T cells (Babu et al. 2005). In addition to cytotoxic T cell which is known as cytotoxic T lymphocyte, cytolytic T cell, CD8+ T- cells or ...
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Decreased T helper 17 cells in tuberculosis is associated with increased percentages of programmed death ligand 1, T helper 2 and regulatory T cells
... With regards to the extent of disease, the percentages of Th1, Th2 and Th17 cells were lower in the patients with extra-pulmonary TB compared to those with pul- monary TB (Fig. 3) and might influenced the overall ...
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T Helper 1/T Helper 2 Cytokine Imbalance in Respiratory Syncytial Virus Infection Is Associated With Increased Endogenous Plasma Cortisol
... ⫹ T cells. These lymphocytes can be subdivided into 2 subsets, T helper 1 (Th1) and Th2, on the basis of the cytokine profiles they ...1 T cells produce interferon ␥ (IFN- ␥ ), ...
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The Role of Eosinophils in the Regulation of CD4+ T helper 2 Regulated Inflammation
... for T cell ...restricted T cells, and leads to physiological capping of the T cell receptor (Prakken et ...+ T cell proliferative responses, which are further enhanced by the co- expression of ...
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T Helper 2 Cytokines Inhibit Autophagic Control of Intracellular Mycobacterium tuberculosis
... of T cells secreting IL-4 or IL-13 in vivo can be much higher, our range included 10-fold ...upregulate Th2 cytokines (IL-4, IL-5, IL-10, and IL-13), whereas nonviru- lent strains induce Th1 cytokines and ...
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Differentiation of naive CD4+ T cells towards T helper 2 cells is not impaired in rheumatoid arthritis patients
... arthritogenic T-cell activity in RA patients, we have found that IL-7, in the context of synovial accessory cells, strongly stimulates T-cell IFN-γ and tumor necrosis factor alpha production without ...
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Treatment with depleting CD4 monoclonal antibody results in a preferential loss of circulating naive T cells but does not affect IFN gamma secreting TH1 cells in humans
... CD45RA(neg)/R0(pos) T cells. Notably, within the CD45RA(pos) subset, T cells with phenotypic evidence of prior activation, ...IL-4-producing T helper 2 (TH2)-type cells in the ...
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Determinant in Human Immunodeficiency Virus Type 1 for Efficient Replication under Cytokine-Induced CD4+ T-Helper 1 (Th1)- and Th2-Type Conditions
... cloned T-tropic HIV-1 (NL4-3) ...Figure 2 illustrates three JR-CSF-based recombinant viruses with substitutions involving corresponding proviral DNA fragments from NL4-3 and also six NL4-3-based recombinant ...
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Abnormal T regulatory cells (Tregs: FOXP3+, CTLA 4+), myeloid derived suppressor cells (MDSCs: monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC
... Fifty six women with LLABCs (>3 cm, T2-T4, N0-2, M0), enrolled in a study of NAC to evaluate the effect of the addition of capecitabine (Cap) to docetaxel (T) pre- ceded by adriamycin and ...
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Cell fate decision: T helper 1 and 2 subsets in immune responses
... mouse T cells is slow and peaks at approximately 2–3 days after T-cell activation, during which time there is substantial de novo synthesis of JNK protein ...of T-cell activation, at a time ...
10
Plasma levels of monokine induced by interferon-gamma/chemokine (C-X-X motif) ligand 9, thymus and activation-regulated chemokine/chemokine (C-C motif) ligand 17 in children with Kawasaki disease
... (ESR). T cells activation has been reported to be participated in the immunological pathogenesis [3, 4], and some pro- inflammatory cytokines of T cells, such as interleukin-4 (IL-4), interferon-gamma ...
6
SOCS2 regulates T helper type 2 differentiation and the generation of type 2 allergic responses
... produce, namely IL-4, IL-5, and IL-13. These type two cytokines drive elevated serum IgE and infiltration of Th2 cells, eosinophils, and baso- phils, which have been observed in patients with asthma and AD (Venge ...
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Multiple myeloma presenting as cutaneous leukocytoclastic vasculitis and eosinophilia disclosing a T helper type 1/T helper type 2 imbalance: a case report
... Our patient was diagnosed as having MM IgG-κ chain type, stage IIIA according to the Durie-Salmon system and stage II according to the International Sta- ging System. Following a definite diagnosis, she re- ceived a VRD ...
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Decoy receptors in the regulation of T Helper cell type 2 response
... major Th2 cyto- kines to such disease ...that Th2 responses are highly complex and might be regulated at many levels through a multitude of pathways, including temporal and spatial regulation of both ...
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HIV integrase and the swan song of the CD4 T cells?
... Considering NHP models, a simple question must be asked –WHY do these viruses, albeit “cytolytic” after in vitro stimulation, not cause in their hosts a very rapid depletion of CD4 T lymphocytes, in all models of ...
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Enhanced IgG4 production by follicular helper 2 T cells and the involvement of follicular helper 1 T cells in the pathogenesis of IgG4 related disease
... We observed that activated Tfh2 cells (CCR7 low PD- 1 high ) were increased in patients with IgG4-RD compared to patients with pSS or MCD, and compared to HCs. Importantly, the expression of CCR7 on T cells is ...
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A detailed phenotypic analysis of immune cell populations in the bronchoalveolar lavage fluid of atopic asthmatics after segmental allergen challenge
... subsets: T cells were identified as CD4 or CD8, as naïve (CD45RA) or memory (CD45RO), and surface phenotyped for CD28, CD25 or ...Regulatory T cells were identified by staining with CD4, CD25 and ...
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Helper T cells in flavivirus infection
... Recently the YF, West Nile dengue type 2 al., DEN2 encephalitis of yellow fever Rice et amino {SLE and virus genomes have been investigated 1985, 1986; Dalgarno et al., 1986a; amino-term[r] ...
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