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THE  FIRST  GENOME  SEQUENCES

First genome sequences of Achromobacter phages reveal new members of the N4 family

First genome sequences of Achromobacter phages reveal new members of the N4 family

... the genome of JWAlpha showed two de- letions which resulted in a much shorter orf18 with an unclear function and a missing gap of about 1,3 kb that contains a gene for a HNH endonuclease in ...

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Automated design of bacterial genome sequences

Automated design of bacterial genome sequences

... necessary first condition is to define a biologically meaningful fitness function that allows changes that are introduced during the evolution process to be ...

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Investigation of repetitive sequences in the human genome

Investigation of repetitive sequences in the human genome

... 6 Conclusion In chapter two, I first demonstrated the limitation of detecting repeat-mediated(NAHR) inversion from short-read sequencing technology. To solve this problem, I developed a new tool, npInv, to detect ...

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Ribosomal S27a Coding Sequences Upstream of Ubiquitin Coding Sequences in the Genome of a Pestivirus

Ribosomal S27a Coding Sequences Upstream of Ubiquitin Coding Sequences in the Genome of a Pestivirus

... its genome, at least three template switches are ...the genome of CP Rit might have evolved by two separate recombination ...intermediate genome with integration of either S27a or ubiquitin coding ...

8

Transmission of the yeast mitochondrial genome : the impact of intergenic sequences

Transmission of the yeast mitochondrial genome : the impact of intergenic sequences

... were first cut with an appropriate restriction enzyme, and then melted at 100° C for three min in the presence of 50 pg random primers prepared from calf thymus ...

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When are pathogen genome sequences informative of transmission events?

When are pathogen genome sequences informative of transmission events?

... Outbreak reconstruction We reconstructed outbreaker and phybreak simulations using the transmission tree inference algorithms in the outbreaker2 and phybreak packages, respectively, which implement the same models used ...

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Complete genome sequences of two insect-specific flaviviruses

Complete genome sequences of two insect-specific flaviviruses

... A maximum likelihood phylogenetic tree was estimated using the Bayesian Markov chain Monte Carlo method implemented in MrBayes version 3.2.3 [15] sampling across the default set of fixed amino acid rate matrices, with ...

5

Heterochromatic sequences in a Drosophila whole genome shotgun assembly

Heterochromatic sequences in a Drosophila whole genome shotgun assembly

... heterochromatic sequences using ...exceptions. First, computational results derived from Genscan were not judged by their scores, as it was empiri- cally determined that low-scoring Genscan results often ...

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A standard variation file format for human genome sequences

A standard variation file format for human genome sequences

... the first examples of fully sequenced individuals ...human sequences in the public ...whole genome re-sequencing ...personal genome analysis. In response we have developed GVF, the ...

9

Analysis of Human Genome Sequences to Identify Disease Genes

Analysis of Human Genome Sequences to Identify Disease Genes

... CSE, First Capital University of Bangladesh, Chuadanga-7200, ...A genome is the collection of DNAs that comprises an organism Each individual organism’s genome contains the genes and other DNA ...

12

CATH: comprehensive structural and functional annotations for genome sequences.

CATH: comprehensive structural and functional annotations for genome sequences.

... must first at- tempt to isolate the sequences associated with that ...domain sequences assigned to CATH superfamilies have been subclassified into func- tional families ...

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CATH: comprehensive structural and functional annotations for genome sequences

CATH: comprehensive structural and functional annotations for genome sequences

... must first at- tempt to isolate the sequences associated with that ...domain sequences assigned to CATH superfamilies have been subclassified into func- tional families ...

6

Genome-Wide Association Study of HIV Whole Genome Sequences Validated using Drug Resistance

Genome-Wide Association Study of HIV Whole Genome Sequences Validated using Drug Resistance

... HIV genome, there are some ...at genome-wide significance, though given many were nominally significant, this is likely to reflect small sample ...variants. First, we would have had greater power to ...

14

Returning individual research results for genome sequences of pancreatic cancer

Returning individual research results for genome sequences of pancreatic cancer

... usually reported back to participants, although arguments have been made that individual results should be made available in some circumstances [5-7]. Since the first draft of the sequence of the human gen- ome ...

8

FOXM1 binds directly to non consensus sequences in the human genome

FOXM1 binds directly to non consensus sequences in the human genome

... the first being direct inter- action of FOXM1 with target DNA occurring at the majority genomic binding sites, and second being recruit- ment or stabilization by chromatin bound proteins such as ...

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The 3' sequences required for incorporation of an engineered ssRNA into the Reovirus genome

The 3' sequences required for incorporation of an engineered ssRNA into the Reovirus genome

... reovirus genome using 50-nucle- otide deletions, single-nucleotide deletions and nucleotide deletions using ssRNAs with extended 5' sequences Figure 1 Survey of the minimum 3' terminal s2 ssRNA nucleotides ...

11

Inference of Homologous Recombination in Bacteria Using Whole-Genome Sequences

Inference of Homologous Recombination in Bacteria Using Whole-Genome Sequences

... the first 600 bp of genome 4 from the ancestor of genomes 3 and 9, whereas others present more uncertainty, for example the import at position 100 bp on genome 5 that could come from at least six ...

21

Human Cytomegalovirus Genome: Partial Denaturation Map and Organization of Genome Sequences

Human Cytomegalovirus Genome: Partial Denaturation Map and Organization of Genome Sequences

... HCMV DNA molecules to be subjected to partial denaturation or length measurements by electron microscopy were purified through sucrose sedimentation gradients alone; the leading half of [r] ...

16

Arrangement of repetitive sequences in the genome of herpesvirus Sylvilagus.

Arrangement of repetitive sequences in the genome of herpesvirus Sylvilagus.

... The arrangement of repetitive elements within the genome of the oncogenic primate herpesviruses herpesvirus saimiri and herpesvirus ateles is very similar to that of herpesvirus sylvilag[r] ...

5

Inverted repeat sequences in the genome of 'Rhodomicrobium vannielii'

Inverted repeat sequences in the genome of 'Rhodomicrobium vannielii'

... IR DNA hybridized to many bands in restriction digests of R ■ vanni eli i chromosomal DNA suggested that some of these sequences might be repeated within the R. vannielii genome. The crossed-blot ...

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