The Human Genome
Sequencing the Human Genome
... to human health with the ethical ...care, human genome sequencing has, and will continue to have, a large impact on our understanding of human history, evolution, and general ...the ...
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The Sequence of the Human Genome
... the human genome sequence is not as finished as the Drosophila genome was with an effective 13-fold ...the human genome in less than 1 year. Human genome sequencing was ...
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On the sequencing of the human genome
... the human genome. The international Human Ge- nome Project (HGP) used the hierarchical shotgun approach, whereas Celera Genomics adopted the whole-genome shotgun (WGS) ...the human ge- ...
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The PCNA pseudogenes in the human genome
... Background: The proliferating cell nuclear antigen (PCNA) is a key protein in the eukaryotic DNA replication and cell proliferation. Following the cloning and characterisation of the human PCNA gene, the question ...
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Body maps on the human genome
... the human genome ...“ genome homunculus ” : a multi-dimensional, genome-wide body representation extending across chromosome territories of the entire spermcell ...
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Cell maps on the human genome
... How, if at all, do these cartographic phenomena relate to the rest of genetic physiology? Is so extensive a struc- ture as a genomic map merely functionless ornament upon the genome’s terra incognita? As mentioned ...
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CHALLENGES IN THE HUMAN GENOME PROJECT
... repeating experiments than by querying a database. Should that happen, the project could reasonably be called a failure. Some genomic database and software problems are fairly straightforward. Others will push the ...
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2 The Human Genome Project
... The Human Genome Project (HGP) is a worldwide research initiative with the goal of analyzing the complete sequence of human DNA to identify all of the ...the human genome is thus the ...
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Decoding the human genome sequence
... the Human Genome Project was made possible by the remarkable international collaboration which developed from the early ...the genome map ...generating genome sequence information on a large ...
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DNA transposons in the human genome
... the human genome, but they have not been active for the past 37 million ...the human genome any more, many genes made out of their domesticated sequences are ...
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THE HUMAN GENOME PROJECT A REVIEW
... of human genome epidemiology ...the Human Genome Epidemiology Network (HuGE Net) will continue to benefit from the contributions of researchers writing HuGE reviews in their own specialty ...
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14.3 Studying the Human Genome
... Summarize the methods of DNA analysis. State the goals of the Human Genome Project and explain what we have learned so far. Lesson Summary Manipulating DNA Since the 1970s, techniques have been developed ...
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Inversion variants in the human genome: role in disease and genome architecture
... the human genome and to use this map to explore the characteristics and distribution of this form of ...about human inversions and their contribution to human ...of human variation and ...
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Alu pair exclusions in the human genome
... of human Alu size distribution The RepeatMasker scan of the hg18 human genome assembly identifies potential Alu fragments as small as 12 ...haploid genome size of ...the human ...
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The accessible chromatin landscape of the human genome
... The accessible chromatin landscape of the human genome Robert E. Thurman 1,* , Eric Rynes 1,* , Richard Humbert 1,* , Jeff Vierstra 1 , Matthew T. Maurano 1 , Eric Haugen 1 , Nathan C. Sheffield 2 , Andrew ...
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The genetics of regulatory variation in the human genome
... Challenges and approaches for identifying regulatory regions One of the major challenges ahead is to identify the DNA sequences that carry the cis signals for regulation of the spatial and temporal expression of all of ...
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A draft annotation and overview of the human genome
... Concluding remarks The human genome is a capacious resource that will support years of intensive investigation. The quality of the draft sequence has now reached the point that genetic maps can truly be ...
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Endogenous retroviruses in the human genome sequence
... HERVs and disease HERVs have frequently been proposed as etiological cofac- tors in chronic diseases such as cancer, autoimmunity and neurological disease [13]. Unfortunately, despite intense effort from many groups, ...
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A draft annotation and overview of the human genome
... the Human Genome Project to enter a new phase, in which the entire sequence can be analyzed to identify genes, regulatory regions and other genomic elements and ...the genome, as disparate data ...
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The Human Genome: A Patenting Dilemma
... At present, it is uncertain whether publication of sequence data would ren- der downstream discoveries obvious. 267 Much depends on how quickly biotech- nology advances,[r] ...
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