The multiple-marker study
Neurofilament light chain as a biological marker for multiple sclerosis: a meta-analysis study
... Introduction Multiple sclerosis (MS) is a disease of the central nervous system (CNS) usually characterized by relapsing episodes of neurological dysfunction, often followed some years later by progressive and ...
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The Response to Chemotherapy as Prognostic Marker in Multiple Myeloma
... with multiple relapses and/or ineligible for high dose of therapy, DXM alone increases life ...randomized study conducted on 488 pa- tients showed a significantly better progression-free surviv- al of ...
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Evaluation of a genome wide approach to multiple marker association considering different marker densities
... single marker regression, for the real data, and were at the position of the true QTL in the simulated ...single marker regression were large in the Bayesian analysis, while smaller effects were ...current ...
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Multiple marker-traits associations for maize agronomic traits
... Two of them, 3.04 and 8.05, are congruent with the region of associations between a marker and multiple traits identified in this study. Since the bin size of maize chromosome is relatively large and ...
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Saliva soluble HLA as a potential marker of response to interferon-β1a in multiple sclerosis: A preliminary study
... of multiple sclerosis (MS) is not presently ...biological marker of disease activity could potentially serve as a monitor of response to immu- nomodulatory treatment in ...biological marker of ...
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Urinary neopterin: An inflammatory marker of disease activity in multiple sclerosis.
... previous study which included several of the same patients but not the control subjects participating in the present study (Palmer et ...surrogate marker of inflammation in this ...
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Improvement in the diagnostics of iron deficiency anemia using multiple marker combinations
... this study, we investigated and evaluated the performance of a number of biomarkers, including ferritin, soluble transferrin receptor (sTfR), hepcidin, C-reactive protein ( CRP ) and combination markers containing ...
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A two step multiple marker strategy for genome wide association studies
... raise study-design and analytical issues that are still being ...the multiple testing ...a multiple-marker family-based association test used to obtain significance levels of regions at step ...
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Predictive Ability of NGAL as a Marker of Renal Damage: evaluation of Multiple Clinical Settings
... After transplantation, local NGAL production within DGF kidneys contributes to the high circulating level, reflecting the ischemia-reperfusion stress applied to the transplanted kidney before organ withdrawal, during the ...
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Data modeling as a main source of discrepancies in single and multiple marker association methods
... Conclusion Both SMA and haplotype-based methods performed sim- ilarly in detecting the most strongly associated SNPs. The use of raw data increased the number of positive results in comparison to corrected phenotypes. ...
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Comprehensive genomic profiling of IgM multiple myeloma identifies IRF4 as a prognostic marker
... M multiple myeloma (IgM MM) is an extremely rare subtype of multiple myeloma with a poor clinical ...this study, bone marrow aspirates of MM patients, including two cases of IgM MM, were analyzed by ...
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Appropriateness of tumor marker request: a case of study
... The study considered currently used tumour markers requested to all outpatients referred to the Local Health Authority Aulss3 of Veneto Region over one ...tumour marker tests requested for 52,536 patients ...
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Sandlike Appearance of Virchow Robin Spaces in Early Multiple Sclerosis: A Novel Neuroradiologic Marker
... observed multiple high-convexity VRSs, which simulate a sandlike appearance, on brain MR images in several patients during the first episode of neurologic symptoms suggestive of ...present study, we ...
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Loss of heterozygosity as a marker of homologous repair deficiency in multiple myeloma: a role for PARP inhibition?
... this study, we have characterized and quanti- fi ed the presence of global HRD-related LOH (HRD-LOH) in MM patients and have used it as an indicator of HRD that could provide a therapeutic rational for PARP ...
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IN SILICO DIAGNOSIS OF TUBERCULOSIS IN MULTIPLE SPECIES USING SINGLE NUCLEOTIDE POLYMORPHISM AS BIOLOGICAL MARKER
... Tuberculosis is a very deadly disease and the methods existing now to detect this disease will take more time. With the help of these SNP markers, it is easier to identify the disease and cure as soon as possible. SNP ...
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A Next-generation Marker Genotyping Platform (AmpSeq) in Heterozygous Crops: A Case Study for Marker-assisted Selection in Grapevine
... molecular marker types have been utilized for MAS in highly heterozygous crops, including simple sequence repeats (SSR) and single-locus or multi-locus SNP ...with multiple inter- speci fic ...
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Interleukin-6 as inflammatory marker referring to multiple organ dysfunction syndrome in severely injured children
... values display the extent of trauma only in the early period. The presented analysis has several notable limitations. Critics to the presented study could be remarked due to the fact that the MODS score used has ...
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Marker Assisted Breeding to Develop Multiple Stress Tolerant Varieties for Flood and Drought Prone Areas
... of marker-assisted breeding product for drought earlier in IR64 background (Sandhu and Kumar 2017) and now in the present study in Swarna-Sub1 background are successful examples that should encourage ...
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NFKB1 -94ins/delATTG polymorphism is a novel prognostic marker in first line-treated multiple myeloma
... non-randomized study where the decision between bortezomib and non-bortezomib protocols may have been biased in many cases, resulting in an increased number of low risk ISS and FISH patients in the non-bortezomib ...
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Bi-caudate ratio as a MRI marker of white matter atrophy in multiple sclerosis and ischemic leukocencephalopathy
... This retrospective study was conducted in the period from January 2018 to June 2019. It included 115 con- secutive patients (54 (47%) males and 61 (53%) females). The mean age was (+ SD) 52.51 years (+ 18.2); age ...
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