The Nucleus Pulposus
Soft biomaterials as a substitute for the Nucleus Pulposus
... sample. Nucleus Pulposus samples reveal similar results between them, as well as the “Ravioli medium” ...the Nucleus Pulposus or the HM of ...
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Developing a novel functional disc emulator to investigate the nucleus pulposus replacement
... There are many patents [10 – 12], and several studies proposed prosthetic disc [13] that replaces the whole intervertebral disc, or they modeled the synthetic nucleus pulposus (NP), i.e., hydrogel [14, 15]. ...
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Novel immortal human cell lines reveal subpopulations in the nucleus pulposus
... Nucleus pulposus cell models and differentiation protocols Using primary tissue from scoliosis patients as starting material justifies the question whether the primary cul- ture and the immortalized cell ...
16
Curing Kinetics and Mechanical Properties of a Composite Hydrogel for the Replacement of the Nucleus Pulposus
... In Fig. 8, the two hydrogel systems were compared and it can be observed that the concentration of T3 does not influence signifi- cantly the mechanical properties. The values of stress vs strain for dried samples are ...
7
Injectable laminin-functionalized hydrogel for nucleus pulposus regeneration.
... a b s t r a c t Cell delivery to the pathological intervertebral disc (IVD) has significant therapeutic potential for enhancing IVD regeneration. The development of injectable biomaterials that retain delivered cells, ...
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Investigating the Cell Population of the Adult Human Nucleus Pulposus
... Low back and neck pain are prevalent conditions in developed societies, and are linked to degeneration of the intervertebral disc (IVD), where aberrant cell biology, particularly in cells of the nucleus ...
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Injectable bioadhesive hydrogels for nucleus pulposus replacement and repair of the damaged intervertebral disc
... 7.4 Conclusions In these studies, an injectable, bioadhesive hydrogel system was developed which has the potential to serve as a synthetic replacement for the nucleus pulposus of the intervertebral disc or ...
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A complex interaction between Wnt signaling and TNF α in nucleus pulposus cells
... nucleus pulposus. During development, the highly hydrated nu- cleus pulposus is populated by clusters of large vacuolated notochordal cells of distinct molecular ...herniation, nucleus ...
11
Original Article Identification and quantitative analysis of extracellular matrix in rabbit nucleus pulposus and cartilage
... into nucleus pulpo- sus cells and implanted into the degenerative intervertebral disc to repair or replace the degenerative disc tissues ...the nucleus pulposus cells and providing high quality ...
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The effects of oxygen tension and antiaging factor Klothoon Wnt signaling in nucleus pulposus cells
... in nucleus pulposus ...of nucleus pulposus cells. Nucleus pulposus is an avascular tissue, and in some species, pO 2 levels in large discs may be ...of nucleus ...
16
Hydrated nucleus pulposus extrusion in dogs: correlation of magnetic resonance imaging and microsurgical findings
... the nucleus pulposus of such discs was not degenerate, and the extrusion may only involve a little, not or only mildly degenerate part of the nucleus ...
10
Biochemical and Biomechanical Modulation of Nucleus Pulposus Cells Encapsulated in Novel Cellulose-Based Hydrogels
... the nucleus pulposus (NP) with a tissue engineered hydrogel scaffold may provide a biologic therapy capable of restoring the structure and mechanical function of the ...
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Creation of an injectable in situ gelling native extracellular matrix for nucleus pulposus tissue engineering
... surrounding tissue using endogenous enzymes [30–33]. However, to minimize immune rejection of the tissue and to prevent the need for systemic immunosuppression, it is essential to remove cells and antigens. ...
12
Spatial geometric and magnetic resonance signal intensity changes with advancing stages of nucleus pulposus degeneration
... The strength of the current study is using conventional MR images to evaluate the homogeneity and the progres- sive changes of T2-weighted MR signal intensity in the nucleus pulposus. This method needs no ...
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Acute Herniation of Nondegenerate Nucleus Pulposus: Acute Noncompressive Nucleus Pulposus Extrusion and Compressive Hydrated Nucleus Pulposus Extrusion
... TITLE: Acute Herniation of Nondegenerate Nucleus Pulposus: Acute Noncompressive Nucleus Pulposus Extrusion and Compressive Hydrated Nucleus Pulposus Extrusion6. AUTHORS: Steven De Decke[r] ...
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Spontaneous Regression of Herniated Nucleus Pulposus
... Reported here are 11 patients in whom there was unequivocal regression or disappearance of a herniated lumbar disk on follow-up CT study.. Two patients with herniated disks w[r] ...
5
The selective staining and ultrastructure of the rabbit nucleus pulposus
... This appearance is to be expected since osmium is known to preferentially stain the inner leaflet of the plasma membrane and with this method lanthanum has been shown to stain the cell[r] ...
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Laminin-Functionalized Polyethylene Glycol Hydrogels for Nucleus Pulposus Regeneration
... Studies were performed here to test for an ability of the newly synthesized PEG-LM111 biomaterial to promote NP cell retention and survival in the disc space, by following luciferase [r] ...
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Polyurethane scaffold with in situ swelling capacity for nucleus pulposus replacement
... (C) Disc height change of IVDs after dissection and free swelling culture overnight (intact), after partial nucleotomy (defect), after refilling with PU scaffold a[r] ...
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Polyurethane scaffold with in situ swelling capacity for nucleus pulposus replacement
... Polyurethane scaffold with in situ swelling capacity for nucleus pulposus replacement LI, Zhen, LANG, Gernot, CHEN, Xu, SACKS, Hagit, MANTZUR, Carmit, TROPP, Udi, MADER, Kerstin T. ...
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