the outer mitochondrial membrane
Phosphatidylglycerol containing ER transport vesicles built and restore outer mitochondrial membrane and deliver nuclear DNA translation products to generate cardiolipin in the inner mitochondrial membrane
... crude mitochondrial pellet was suctioned off, the pellet was gently resuspended in five volumes of medium consisting of ...the Outer Mitochondrial Membrane ...Inner Mitochondrial Space ...
14
The Taz1p Transacylase Is Imported and Sorted into the Outer Mitochondrial Membrane via a Membrane Anchor Domain
... the membrane anchor is mutated (V224R), Taz1p alters its normal import course and does not reach the outer mitochondrial ...of membrane proteins and protect them from the aqueous environment ...
9
VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis
... the mitochondrial surface is closely apposed to ER membranes ...the outer mitochondrial membrane protein PTPIP51 and that a proportion of VAPB is present in ...
13
Schreiner, Bernadette (2013): Role of the AAA protease Yme1 in folding of proteins in the mitochondrial intermembrane space. Dissertation, LMU München: Fakultät für Biologie
... the outer mitochondrial ...of mitochondrial proteins regulate the morphological dynamics of the organelle (Shaw and Nunnari, ...the mitochondrial intermembrane space (Youle and van der Bliek, ...
127
Game and Players: Mitochondrial Apoptosis and the Therapeutic Potential of Ursodeoxycholic Acid
... and mitochondrial pathways of cell death (Li et ...subsequent mitochondrial translocation (Eskes et ...the outer mitochondrial membrane (Kim et ...induce mitochondrial ...
17
Two Membrane-Associated Regions within the Nodamura Virus RNA-Dependent RNA Polymerase Are Critical for both Mitochondrial Localization and RNA Replication
... integral membrane protein with MAR structures that play critical roles in RC formation, it is not yet clear how this interaction is ...tegral membrane proteins that interact with mitochondrial mem- ...
15
High expression of α-synuclein in damaged mitochondria with PLA2G6 dysfunction
... and membrane re- modeling [13, ...inner membrane pro- tein (cytochrome c oxidase, CCO), and positive for an outer membrane protein (translocase of the outer mitochondrial ...
16
Hepatitis B Virus HBx Protein Localizes to Mitochondria in Primary Rat Hepatocytes and Modulates Mitochondrial Membrane Potential
... from mitochondrial membrane depolarization ...on mitochondrial membrane depo- larization was examined; TNF- ␣ is a cytokine produced in the context of a chronic HBV infection and can be used ...
14
Therapeutic Modulation of Apoptosis: Targeting the BCL 2 Family at the Interface of the Mitochondrial Membrane
... 1. Mitochondrial membranes are sites of dynamic events during ...the outer mitochondrial membrane (OMM), membrane-associated BAX monomers (dark red) are found in close association with ...
9
Differential Proteomics Analyses Reveal Anxiety-Associated Molecular and Cellular Mechanisms in Cingulate Cortex Synapses
... The mitochondrial voltage-dependent anion channels (Vdac1, 2 and 3) facilitate metabolite flux by enabling transport of ATP, ADP, NADH, phosphocreatine, Ca 2+ and other small ions across the outer ...
18
Nifedipine and Nitrendipine Stimulate Cholesterol Hydroxylation in Rat
... inner mitochondrial membranes by a mechanism coupled to peripheral benzodiazepine receptors ...to mitochondrial peripheral benzodiazepine receptors in ...the outer mitochondrial ...
9
Apocynin prevents mitochondrial burdens, microglial activation, and pro-apoptosis induced by a toxic dose of methamphetamine in the striatum of mice via inhibition of p47phox activation by ERK
... For Western blot analysis of phospho (p)-p47phox, p- ERK, p-p38, p-JNK, Iba-1, cleaved caspase 3, and TH, striatal tissues were lysed in buffer containing a 200 mM Tris–HCl (pH 6.8), 1 % SDS, 5 mM EGTA, 5 mM EDTA, 10 % ...
22
The C-Terminal Region of Rift Valley Fever Virus NSm Protein Targets the Protein to the Mitochondrial Outer Membrane and Exerts Antiapoptotic Function
... integral mitochondrial outer membrane (MOM) protein, Tom20, or an endoplasmic reticulum marker, calreticulin, followed by incubation with Alexa Fluor-conjugated secondary antibodies (Molecular ...the ...
7
Meins, Thomas (2008): Structural basis of the mitochondrial voltage-dependent anion channel VDAC I. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... the outer mitochondrial membrane, but also gets influenced by these interactions, becomes obvious by further distinct shift changes at the Cterminal end of the Nterminal helix and its connecting ...
135
Detection of Chlamydia pneumoniae Specific Antibodies Binding to the VD2 and VD3 Regions of the Major Outer Membrane Protein
... tis. Notably, all sera that tested positive only for C. pneumoniae reacted with OMP2 from both C. pneumoniae and C. tracho- matis (Fig. 4B). Likewise, C. trachomatis immune sera dis- played OMP2 reactivity at ...
6
Neuroprotective Effects of Caffeine on a Maternally Separated Parkinsonian Rat Model
... Maternal separation plays a major role in affecting proper development of the neurocircuitry. These disruptions early in life have enduring effects and predispose the rat to be particularly vulnerable to ...
8
Cardiolipin Synthesis and Outer Membrane Localization Are Required for Shigella flexneri Virulence
... and outer membranes, is synthesized primarily by the putative cardiolipin syn- thase ClsA in Shigella ...its membrane, grew normally in vitro, and invaded cultured epithelial cells, but it failed to form ...
16
Preferential Packing of Acidic Glycosidases and Proteases into Bacteroides Outer Membrane Vesicles
... Sugar-hydrolyzing activity of OMV. The proteomic analysis of OMV revealed the presence of several proteins annotated as sugar hydrolases (see Table 1; also see Table S2 in the supplemen- tal material). These included ...
12
HIV 1 protease induced apoptosis
... the mitochondrial surface, likely at the inner ...this mitochondrial loca- lization was independent of HIV-1 PR ...cleave mitochondrial proteins, which would lead to loss of mitochondrial in- ...
15
Hematoma within the Outer Membrane of the Arachnoid Cyst Located in the Middle Fossa: A Mechanism of Development of Chronic Subdural Hematoma Associated with Arachnoid Cysts
... the outer membrane of the subdural hematoma demonstrated that the arachnoid cell layer on the inside of the outer membrane (facing the cyst cavity), and collagen fibers covered the outside of ...
7