The rational for developing clinical outcome measures
Clinical outcome measures in juvenile idiopathic arthritis
... quantitative measures will in- crease the reliability of comparison of patient populations and the analysis of the effectiveness of current and novel therapeutic ...most outcome measures described in ...
8
Outcome Measures for Clinical Trials: Status of Task Force
... 1. CDISC data standard for MS: Will improve ability to compare data across studies, to interpret findings, and to analyze pooled datasets. 2. A database of pooled, de-identified clinical trial data mapped to the ...
17
The performance of the Health of the Nation Outcome Scales as measures of clinical severity.
... 19 with the HoNOS across different diagnostic categories. Therefore, future investigations of the HoNOS’s performance in a more disease specific context should include more specific measures. Second, there was a ...
37
Summary of Clinical Outcome Measures for Sports-Related Knee Injuries
... Reliability, validity, and responsiveness of four knee outcome scales for athletic patients. J Bone Joint Surg Am. 2001;83:1459-69 5) Greco NJ, Anderson AF, Mann BJ, Cole BJ, Farr J, Nissen CW, Irrgang JJ. ...
391
Outcome measures in clinical trials of treatments for acute severe haemorrhage
... of outcome measures commonly used in trials of haemostatic treatments, including all-cause and cause-specific mortality, blood transfusion and surgical ...
7
THERAPY DEVELOPMENT AND CLINICAL OUTCOME MEASURES FOR DUCHENNE MUSCULAR DYSTROPHY
... the clinical and genetic description of Becker patients, and the occurrence of asymptomatic subjects carrying intragenic deletions in the DMD gene 133 ...for clinical beneficial ...with clinical ...
163
Outcome measures in clinical trials of treatments for acute severe haemorrhage.
... appropriate outcome measures for clinical trials of haemostatic ...of outcome measures commonly used in trials of haemostatic treatments, including all-cause and cause-specific ...
8
<p>Developing a Preliminary Conceptual Framework for Guidelines on Inclusion of Patient Reported-Outcome Measures (PROMs) in Clinical Quality Registries</p>
... clinical domains, such as surgery, 27,28 spinal osteopathy services, 31 cancer, 30,32 and total joint arthroplasty. 29 Settings for PROs Data Collection In general, studies included in the review either provided ...
18
Developing core outcome sets for clinical trials: issues to consider
... the clinical setting; for example, for breast reconstructive surgery, which is an optional procedure undertaken for cosmetic purposes, the involvement of patients is more critical than in other ...
8
Responsiveness of clinical and ultrasound outcome measures in musculoskeletal systemic lupus erythematosus
... recent clinical trials of sifa- limumab and anifrolumab, the CLASI showed a high rate of responsiveness [34, ...composite outcome measure could be designed for mus- culoskeletal disease that offers similar ...
8
Outcome Measures for Traditional and
... 96 traditional and 42 accelerated graduates within the last 18 months. The research- ers queried nurse managers through focus groups about the readiness of these graduates to begin practice. The managers in this study ...
7
Clinical features, predictive factors and outcome of hyperglycaemic emergencies in a developing country
... Methods: This study was carried out in DM patients who presented to an urban hospital in Nigeria with hyperglycaemic emergencies (HEs). The information extracted included biodata, laboratory data and hospitalization ...
5
Interpreting the results of patient reported outcome measures in clinical trials: The clinician's perspective
... the outcome of interest that informed patients or informed proxies perceive as important, either beneficial or harmful, and that would lead the patient or clinician to consider a change in the ...
8
Guidance on the implementation of Patient Reported Outcome Measures (PROMs) in clinical palliative care
... in clinical care, following distinctive steps and illustrated by recommendations for the POS family ...good clinical practice is always reliant on sound clinical assessment and reasoning related to ...
36
Functional outcome measures for NF1-associated optic pathway glioma clinical trials
... NF1-OPG clinical trials is complicated by a number of factors, including the potential differential impact of VA vs VF loss, the use of parent proxy reporting, the wide age range of subjects enrolled, and the ...
12
Clinical outcome measures for monitoring physical function in pediatric obesity: An integrative review
... performance‐based measures of physical ...performance measures reported, only 6 minute‐timed‐walk (6MTW) was examined for test‐retest ...repeatability. Measures of flexibility, strength, aerobic ...
28
OBESITY DRUG OUTCOME MEASURES
... in clinical trials, may manifest with wide usage of obesity drugs – as with any drug used by a significant number of patients over a period longer than a clinical ...
29
Validity of Bronchiolitis Outcome Measures
... be caused by measurement error rather than change per se. 35 At the individual level, taking repeated measurements and averaging the value would reduce the measurement error with a factor √ k (k is the number of ...
12
Patient-reported Outcome Measures
... available measures, ideally in comparison with each other, will assist in the selection of the most appropriate ...within clinical practice, this may change over time, as clinicians become more familiar ...
8
Outcome Measures in Childhood Asthma
... Outcome Measures in Childhood Asthma David ...asthma outcome measures are either impractical or unreliable in preschool-aged ...ventional measures of pulmonary function such as spi- ...
8