The study of DNA complexes
Computational Methods for Mass Spectrometry-based Study of Protein-RNA or Protein-DNA Complexes and Quantitative Metaproteomics
... We developed the mzTab file format for communication and statistical downstream analysis of experimental results in proteomic and metabolomic studies. We chose a simple structured tabular-separated format and CV terms ...
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Theoretical Study of Structural Relationships and Electrochemical Properties of [DNA-Nucleotide Bases]@Cn Complexes
... of DNA and other nucleic acids to create self-assembling branched DNA complexes with useful ...properties. DNA is thus used as a structural material rather than as a carrier of biological ...
11
Photo-thermal effects in gold nanorods/DNA complexes
... sive study of the electrostatic interaction between an aqueous solution of positively charged GNRs dispersed in a negatively charged short chain DNA solution is ...the DNA melting in the prepared ...
9
High-resolution AFM imaging of single-stranded DNA-binding (SSB) protein DNA complexes
... In this article, we present high-resolution AFM images in air of ssDNA–E. coli SSB nucleoprotein filaments adsorbed on mica at both low and high ionic strengths. Partly and fully saturated ssDNA nucleoprotein filaments ...
8
Cleavage of Lipids and DNA by Metal Ions and Complexes
... at ~ pH 4.8. All of the ratios in Figure 2.7 are above 1, indicating that cerium(IV) hydrolyzes lipid vesicles of sphingomyelin and phosphatidylcholine more efficiently at lysosomal pH. Interestingly, under any given ...
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Study of Proteoforms, DNA and Complexes using Trapped Ion Mobility Spectrometry-Mass Spectrometry
... the study of kinetically trapped intermediates of ...this study, we presented the folding pathways between local, free energy minima of AT- hook peptide 3 (ATHP3) leading to multiple, stabilized ...
253
Reactivity and structural studies of metal complexes bound to DNA
... limited study of the effect of intervening mismatches on long-range guanine oxidation (10), and they concluded that any attenuation in long-range oxidation arose from a competition between trapping of a guanine ...
29
Direct observation of DNA threading in flap endonuclease complexes
... bifurcated DNA to generate sealable nicks has been the subject of debate since Lyamichev and co-workers proposed that the single-stranded 5′-flap branch might thread through a FEN protein 10 ...double-stranded ...
34
Highly disordered histone H1-DNA model complexes and their condensates.
... to study separately the stages before and after complex ...to study the effect of phosphorylation. We find that the complexes contain highly disordered CH1, and form phase-separated droplets, which ...
26
Impact of human MLL/COMPASS and polycomb complexes on the DNA methylome
... this study was to determine how histone modifications functionally interface with, or regulate, genome-wide CpG methylation ...PRC2 complexes on the human DNA methylome as these three marks have the ...
15
DNA Cleavage Activity of Copper (II) Complexes of Some Phosphonates
... buffer was used as a control. The reactions were carried out at 37 ˚C at different time points (0, 0.5, 1, 2, 6, 12 hours). A solution of loading dye (0.05% bromophenol blue, 5% glycerol, and 2 mM EDTA) was added to the ...
9
Synthesis, characterization, DNA binding, DNA cleavage, protein binding and cytotoxic activities of Ru(II) complexes
... to DNA and, thus, feature indeed ruthenium-based cisplatin analogs, other complexes rather possess modes of action similar to NAMI-A and attack metastases while being widely non-toxic to cancer cells in ...
8
Comparison of DNA lipid complexes and DNA alone for gene transfer to cystic fibrosis airway epithelia in vivo
... of DNA–lipid to DNA ...scribed DNA–lipid vectors. Therefore, we tested the hypoth- esis that DNA–lipid complexes were more effective than DNA alone at transferring CFTR cDNA to ...
10
Effect of TDP2 on the Level of TOP2-DNA Complexes and SUMOylated TOP2-DNA Complexes
... Abstract: DNA topoisomerase II (TOP2) activity involves a normally transient double-strand break intermediate in which the enzyme is coupled to DNA via a 5 0 -phosphotyrosyl ...covalent complexes ...
16
Metal complexes as DNA intercalators
... Os complexes containing multi heterocyclic aromatic ligands such as phen, phi or dppz, chrysi, phzi, dpq, dppn and eilatin ...specific DNA sites by matching the shape, symmetry, and functionalities of the ...
46
The Smc complexes in DNA damage response
... mediate DNA repair are not ...their DNA repair functions are separ- able from their major functions in sister-chromatid cohesion and chromosome ...the DNA repair func- tions of the Smc ...
11
An overview of the structures of protein DNA complexes
... and DNA to adopt distinct conformations, resulting in multispecific ...the DNA sequence it ...for DNA base recognition will be family specific, but with underlying trends such as the arginine-guanine ...
37
Bacteriophage T7 DNA Synthesis in Isolated DNA-Membrane Complexes
... DNA- membrane complexes from T7 infected cells were isolated and incubated in the standard reaction mixture, and the DNA was extracted as described in Methods. Repair of the isolated DNA[r] ...
8
Experimental Renal Disease Induced by DNA—Anti DNA Immune Complexes
... subendothelial deposits were seen. Sucrose density gradient analyses of sera immediately after antigen injections suggested the presence of immune complexes of DNA and antibody since both heavy sedimenting ...
12
Targeting DNA Mismatches with Luminescent Ruthenium Complexes
... progression, DNA mismatches are a promising target in the design of small molecule therapeutics and ...metal complexes are prime candidates, owing to their valuable spectroscopic and photophysical ...
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