Therapeutic approaches
Developing therapeutic approaches for metachromatic leukodystrophy
... Notes: The figure shows the biosynthetic pathways of sulfatide, the sphingolipid that accumulates during metachromatic leukodystrophy MLD. The specific enzymes described in each step of the pathway are in italics. The ...
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Current therapeutic approaches for plantar fasciitis
... ing age, which may induce plantar fascia degeneration and increased mechanical overload, is considered a risk factor for PF, the true pathogenesis remains unknown. A literature search for “articles about plantar ...
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Novel therapeutic approaches in chondrosarcoma.
... Chondrosarcoma is a malignant tumor of bones, characterized by the production of cartilage matrix. Due to lack of effective treatment for advanced disease, the clinical management of chondrosarcomas is exceptionally ...
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Oligonucleotide therapeutic approaches for Huntington disease
... major approaches to therapeutic gene suppression (Figure ...Both therapeutic approaches require adequate in vivo delivery of drug; this critical aspect for drug development is discussed in ...
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Therapeutic approaches enhancing peripheral nerve regeneration
... research therapeutic ap- proaches, potentially orientated to accelerate nerve re- generation and recovery of nerve ...the therapeutic approaches discussed appears ...
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Therapeutic Approaches to Hypertension in Kidney Disease
... existed therapeutic approaches for the management of hypertension in patients with renal disease for reducing the risk of CVD and slowing the progression of kidney ...
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THERAPEUTIC APPROACHES FOR THE TREATMENT OF PULMONARY HYPERTENSION
... [17] They are used in patients with idiopathic pulmonary arterial hypertension (IPAH) who demonstrate a favorable response to acute vasodilator testing.. [1] In a la[r] ...
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Inclusion body myositis: therapeutic approaches
... the therapeutic dilemma in IBM ...this therapeutic dilemma is the prohibitive expense and occasional scarcity of this drug, along with the potential for side effects such as infusion reactions and ...
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Inflammasome inhibitors: promising therapeutic approaches against cancer
... Andrographolide is a labdane diterpenoid that has been isolated from the stem and leaves of Andrographis pani- culata [112]. Numerous studies have validated the facts that andrographolide can inhibit cell invasion and ...
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Multidisciplinary diagnostic and therapeutic approaches to pancreatic cystic lesions
... Within the group of mucinous PCNs, intraductal papillary mucinous neoplasms (IPMNs) involving the main pancreatic duct are the most worrisome, and surgical resection should [r] ...
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THERAPEUTIC APPROACHES FOR THE TREATMENT OF DIABETES MELLITUS
... The condition, if not under control, even after step 2, this is a call for the third step, which incorporates either oral triple therapy or introduction of basal insulin (condition appl[r] ...
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Cellular and vaccine therapeutic approaches for gliomas
... immunotherapeutic approaches [21,43-46] few have advanced from the Phase I/II experimental stage to Phase III testing, testimony of the small number of groups with a research focus in immunotherapy and the ...
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ADVANCED THERAPEUTIC APPROACHES TO SORES AND BURNS IN CHILDREN
... The therapy of burns in the last few years presented a progressive evolution and today we can use innovative materials and biotechnologies. The traditional dressings have been integrated with others that paved the way ...
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Therapeutic approaches in myelofibrosis and myelodysplastic/myeloproliferative overlap syndromes
... The multi-kinase inhibitor midos- taurin prolongs survival compared with placebo in combination with daunorubicin/cytarabine induction, high-dose consolidation, and as maintenance[r] ...
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Adaptive immunity in atherogenesis: new insights and therapeutic approaches
... The recognition that both innate and adaptive immunity due intimately involved in atherogenesis has provided novel targets to reduce the proinflammatory milieu of the developing atheroscle- rotic lesion, as discussed ...
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New Therapeutic Approaches for the Treatment of Huntington’s Disease
... therapeutic strategies for HD: (a) pharmacological strategy – e.g. replacement of the transmitter, (b) surgical strategy – replacement of degenerated neural tissue by neural graft. The first strategy, i.e. ...
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New therapeutic approaches in alcohol dependence: reduction of consumption as a step in the therapeutic goal
... a therapeutic course of modular treatment aimed at abstinence, the possibility of preven- tion to avoid evolution into more severe forms of alcohol- ism and the need to reduce the social and economic im- pact of ...
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A Review: Influenza and its Therapeutic Approaches
... and therapeutic solutions against epidemic and pandemic ...outbreaks. Therapeutic treatment option for pandemic, seasonal and zoonotic influenza viruses are antiviral neuraminidase ...
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Molecular characterization and targeted therapeutic approaches in breast cancer
... several therapeutic strategies for overcoming trastuzumab resistance have been devel- oped, including lapatinib, pertuzumab, and trastuzumab- DM1 (Table ...
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ALZHEIMER'S DISEASE THERAPEUTIC APPROACHES
... All the neurodegenerative diseases are age prevalent disorders that occur in many individuals commonly nowadays occurs due to the changes in the molecular mechanisms. There are a lot of evidences for neurodegenerative ...
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