Therapeutic Doses
Toxicological evaluation of therapeutic and supra-therapeutic doses of Cellgevity® on reproductive function and biochemical indices in Wistar rats
... supra-therapeutic doses, an increased GSH level was obtained in addition to elevated SOD and CAT ...Highest doses of CGV reduced GST activity in treated ...supra-therapeutic doses of ...
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Gender specific distribution of mefloquine in the blood following the administration of therapeutic doses
... at therapeutic dosage, to assess its correlation with the occurrence of treatment-related adverse events, and to explore the necessity of adjusting treatment guidelines for ...standard therapeutic ...
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Central Anticholinergic Syndrome on Therapeutic Doses of Cyproheptadine
... child on hemodialysis weighing only 17 kg devel- oped CAS after cyproheptadine was prescribed as an appetite enhancer. The intended daily dose was 8 mg (0.5 mg/kg). The parents mistakenly admin- istered him two ...
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Gigantic retroperitoneal hematoma as a complication of anticoagulation therapy with heparin in therapeutic doses: a case report
... Case presentation: We report the case of a patient with coronary artery disease who presented with transient ischemic attack, in whom anticoagulant therapy with heparin precipitated a ma[r] ...
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ANALYTICAL STUDY OF MERCURY AND SAATHILINGAM USED IN SIDDHA MEDICINE BY THE PROCESSES OF SUTHTHI
... methods, therapeutic doses, disease condition(severity of the diseases), age and strength of the patient, duration of drug uses and anupanam(vehicle) of the mercury and saathilingam containing drugs ...
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Synthesis and pharmacological study of 4 (2 oxopropylidene) 1,5 benzodiazepin 2 one and its alkylated derivatives
... We have studied the psychotropic activity of 4-acetonylidene-1,5 benzodiazepine -2 -one and its alkylated derivatives. The results indicate that the products tested were not toxic at therapeutic doses and ...
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IDENTIFICATION AND QUANTIFICATION OF LUPEOL IN FORMULATION CONTAINING FICUS SPECIES USING HIGHPERFORMANCE THIN LAYER CHROMATOGRAPHY
... a therapeutic and chemopreventive agent for the treatment of inflammation and ...effective therapeutic doses exhibits no toxicity to normal cells and tissues, [13] and protective against glutamate ...
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EFFECT OF THERAPEUTIC LITHIUM CARBONATE DOSES ON RAT BRAIN CONTENT OF MOOD REGULATING NEUROTRANSMITTERS
... reduction of inositol 1, 4, 5-trisphosphate (IP3) levels [26]. An Ample evidence elucidated that dysfunction of serotoninergic neurotransmission in CNS is involved in the evolution of anxiety, depression and memory ...
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The combination therapy with alfacalcidol and risedronate improves the mechanical property in lumbar spine by affecting the material properties in an ovariectomized rat model of osteoporosis
... sub-therapeutic doses was more effective than the each monotherapy; (2) in the suppression of bore resorption and the amelioration of microstructural parameters, the effects of ALF and RIS were considered ...
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Anti-Inflammatory and Analgesic Activity of Dopamine Antagonists and their Interaction with Aspirin in Wistar Rats
... clinical doses and their synergistic activity with SAI dose of ...the therapeutic doses of aspirin, provided the observations of the present study could be extrapolated to human ...
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Report of the Subcommittee on Disease-Related Pain in Childhood Cancer
... In the treatment of the pain and air hunger associated with terminal malignancy, therapeutic doses of opioids should not be limited by excessive concerns regarding respiratory depression[r] ...
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Journal of Applied Pharmaceutical Science
... long-term therapeutic doses of benzodiazepines was well tolerated in all patients when judged by the absence of precipitated seizures, psychosis, or other serious withdrawal symptoms, or the need for ...
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... to therapeutic doses and duration of antibiotics, they prescribed and dispensed these antibiotics inappropriately regardless to actual clinical needs of their ...
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Dose-linearity of the pharmacokinetics of an intravenous [C-14]midazolam microdose in children
... and scientific challenges. Children are vulnerable, and so exposing them to (almost) therapeutic doses of drugs for a nontherapeutic rea- son, as in a phenotyping study, may not be ethically acceptable. ...
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Deflazacort: therapeutic index, relative potency and equivalent doses versus other corticosteroids
... The anti-inflammatory effect of corticosteroids is one of the main reasons for the use of these therapeutic agents. Several studies on adrenal steroids with glucocorticoid activity have led to the synthesis of new ...
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Galleria mellonella (greater wax moth) larvae as a model for antibiotic susceptibility testing and acute toxicity trials
... of bacteria and incubated for 2 h at 37 °C [3, 12, 13]. After the incubation the larvae were injected in the last right proleg with the lowest dose of antibiotic (5 mg/ kg body weight) and returned to incubation at 37 ...
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Implementation and evaluation of an algorithm for the management of scabies outbreaks
... two doses of ivermectin one week apart and does not expli- citly consider the application of permethrin as a thera- peutic option [3], the Centers of Disease Control and Prevention (CDC) guideline not even ...
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The combined effects of extracorporeal membrane oxygenation and renal replacement therapy on meropenem pharmacokinetics: a matched cohort study
... wide therapeutic index of meropenem, highly variable CrCL between ECMO patients based on modal- ity and intensity of RRT used, loss in the ECMO circuit and preponderance of less susceptible organisms in this ...
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Antifungal activity of <em>Cardiospermum halicacabum</em> L. (Sapindaceae) against <em>Trichophyton rubrum</em> occurs through molecular interaction with fungal Hsp90
... Introduction: Dermatophytosis is a superficial fungal infection limited to the stratum corneum of the epidermis, or to the hair and nails, and constitutes an important public health problem because of its high prevalence ...
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Influence of Tetracyclines on Inflammation and their Interaction with Aspirin in Male Wistar Rats
... subtherapeutic doses of various tetracyclines used in the present study showed mutual synergistic anti-inflammatory activity, without significant ulcerogenicity of gastric ...
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