therapeutic index
Electrochemotherapy with cisplatin enhances local control after surgical ablation of fibrosarcoma in cats: an approach to improve the therapeutic index of highly toxic chemotherapy drugs
... a therapeutic gain when ECT is added to the surgical protocol and compare favorably with the results obtained by our group in a previous study of ECT in cats with soft tissue sarcomas ...the therapeutic ...
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Selective DNA PKcs inhibition extends the therapeutic index of localized radiotherapy and chemotherapy
... Our data with NU5455 indicates that there is the potential to realize a differential potentiation of radiation-induced DNA dam- age in tumor versus normal tissues by transient DNA-PKcs inhibition in vivo. This is based ...
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NanoDisk containing super aggregated amphotericin B: a high therapeutic index antifungal formulation with enhanced potency
... The biological basis for super aggregate AMB’s improved therapeutic index remains controversial, along with the mechanism of action and toxicity of the drug in general. One compelling line of evidence, ...
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Troubled by warfarin s narrow therapeutic index, numerous
... narrow therapeutic index, nu- merous medication and dietary interactions, and need for frequent monitoring, patients requiring long- term oral anticoagulation therapy have been seeking alterna- tives for ...
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Prophylactic Alpha Interferon Treatment Increases the Therapeutic Index of Oncolytic Vesicular Stomatitis Virus Virotherapy for Advanced Hepatocellular Carcinoma in Immune-Competent Rats
... the therapeutic index in tumor-bearing rats by prophylactic administration of IFN- ␣ ...novel therapeutic modality for patients with advanced HCC, as well as other types of ...
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Nanoparticulate <em>Quillaja saponin</em> induces apoptosis in human leukemia cell lines with a high therapeutic index
... ASAP in the KGI particulate form caused U937 cancer cell death at low concentrations; 30-fold lower than what was required to kill the normal human monocytes or DCs, ie, a high therapeutic index was ...
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NARROW THERAPEUTIC INDEX DRUGS A CRITICAL STUDY ON PRESCRIPTION TRENDS IN SOUTH INDIAN TERTIARY CARE HOSPITAL
... The therapeutic index (TI) is a comparison of the amount of a therapeutic agent that causes the therapeutic effect to the amount that causes ...terms therapeutic window or safety window ...
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PROSPECTIVE STUDY ON DRUG DRUG INTERACTIONS OF NARROW THERAPEUTIC INDEX DRUGS
... Narrow therapeutic index drugs are drugs where small differences in dose or blood concentration may lead to serious therapeutic failures and / or adverse drug reactions that are life- threatening or ...
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cause harmful and unwanted toxicity to normal cells. The therapeutic index of chemotherapy is
... The therapeutic index of chemotherapy is reported as 6:1 which means that for every 6 tumour cells killed by chemotherapy, one normal cell is killed 1 ...the therapeutic index has been ...
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Intestinally-restricted Janus Kinase inhibition: a potential approach to maximize the therapeutic index in inflammatory bowel disease therapy
... Results: Tofacitinib, dosed orally or intracecally, inhibited, with similar efficacy, oxazolone-induced colitis, represented by improvements in the disease activity index and its sub-scores (body weight, stool ...
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Deflazacort: therapeutic index, relative potency and equivalent doses versus other corticosteroids
... The efficacy of treatment was evaluated in each group at day 0, 90, 180, 240, and 360. Clinical efficacy parameters included: number of swollen joints; number of tender joints; pain measured by means of a Visual Analogue ...
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The characteristic index vs. the market index
... Characteristic Index benchmarks used, different estimation procedures neither changed the sign nor the significance of post-listing abnormal ...Market Index benchmarks used, different estimation procedures ...
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A Portfolio on the Therapeutic Relationship, Therapeutic Ruptures and Repairs, and Counselling Psychology
... strived to maintain an empathic and compassionate stance during the interview, attempting to enter participants’ world and allow participants’ stories to unfold without leading them or constraining them in any way. In ...
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Bile reflux index after therapeutic biliary procedures
... noted, therapeutic biliary procedures impair the function of the sphincter of Oddi, leading to uncontrolled flow of bile into the ...of therapeutic biliary procedures on DGR and the results are ...
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Index
... Boston College Annual Survey of Massachusetts Law (1980) "Index," Annual Survey of Massachusetts Law: Vol.s. uniform rules, 384-88 Commercial Law.[r] ...
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Index
... Boston College Annual Survey of Massachusetts Law (1983) "Index," Annual Survey of Massachusetts Law : Vol.[r] ...
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Index
... Boston College Annual Survey of Massachusetts Law (1982) "Index," Annual Survey of Massachusetts Law : Vol.[r] ...
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Index
... Boston College Annual Survey of Massachusetts Law (1981) "Index," Annual Survey of Massachusetts Law : Vol.. parent's religious indoctrination and to child, 96-7[r] ...
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Cumulative Index: Index Digest
... It has been accepted for inclusion in Montana Law Review by an authorized editor of The Scholarly Forum @ Montana Law.. Recommended Citation.[r] ...
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