Therapeutic Potential
The therapeutic potential of epigenetic manipulation during infectious diseases.
... interesting therapeutic approach as it would be possible to either target RomA speci fi cally to prevent the trimethylation of H3K4 or use histone acetyl transferase or CRISPR-Cas9 (as discussed below) to inhibit ...
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AN OVERVIEW OF THERAPEUTIC POTENTIAL OF THYMOQUINONE
... increasing the activity of quinine reductase, superoxide dismutase, catalase and glutathione transferase and inhibition of NF-κB activity 50 . Toxicological Studies: Increased interest in phytomedicine, brings health ...
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REVISITING ANCIENT THERAPEUTIC POTENTIAL OF AYURVEDIC BHASMA
... ABSTRACT: With the advent of nanotechnology, it has become important to realize the immense potential of ayurvedic bhasma which had been there for centuries. The study of ayurvedic bhasma as nanomedicine is an ...
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The therapeutic potential of modulating the ceramide/sphingomyelin pathway
... Manipulation of ceramide levels may also enhance the effectiveness of some cancer therapies. Wanebo and coworkers showed that the addition of ceramide enhances taxol-mediated apoptotic death of Tu138 head and neck tumor ...
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The Therapeutic potential of lentivector delivered RNAi
... Many of the human cancer genes identified to date involve chromosomal translocations (Futreal et al. 2004). Where the chromosomal translocation results in a chimeric mRNA that contains a tumour-specific sequence at the ...
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The therapeutic potential of plant flavonoids on rheumatoid arthritis
... novel therapeutic approach targeting rheumatoid arthritis by combined administration of morin, a dietary flavanol and non-steroidal anti-inflammatory drug indomethacin with reference to pro-inflammatory cytokines, ...
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Neuroinflammation in Parkinson’s disease and its potential as therapeutic target
... Minocycline is a semi-synthetic, second-generation tetracycline analog, which, as a lipophilic molecule, can easily get through the BBB and has been reported to have anti-inflammatory and neuroprotective properties in ...
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Hapln2 in neurological diseases and its potential as therapeutic target
... its potential role in the UPP, it has been identified as a contributor to the pathological processes in several neurological ...the therapeutic potential of Hapln2 in neurological ...
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Sphingolipid and ceramide homeostasis : potential therapeutic targets
... thase demonstrated mammalian toxicity [93]. In contrast the post-ceramide divergence represented by the absence of IPC synthase and inositol-based sphingolipids in mammalian cells, highlights the therapeutic ...
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Placenta-derived cells for acute brain injury
... motor function, sensory function, balance, joint range of motion, and joint pain, and by Functional Independence Measure (FIM) 127 , a multi-item rating scale assessing self- care, bowel and bladder management, mobility, ...
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Therapeutic potential of flavonoids in spinal cord injury
... numerous others. TCM has provided classic herbal medicine for treating spinal cord injury diseases in the clinic for many years. It was found that the main active components are flavonoids by using modern pharmacological ...
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The biology of DHX9 and its potential as a therapeutic target
... DHX9’s interaction with an extensive and varied array of nuclear and cytoplasmic protein and nucleic acid partners indicates that it holds a privileged position as a central regulator of gene expression. Although much ...
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The immunocytokine NHS-IL12 as a potential cancer therapeutic
... Targeted delivery of IL-12 might turn this cytokine into a safer, more effective cancer therapeutic. Here we describe a novel immunocytokine, NHS-IL12, consisting of two molecules of IL-12 fused to a tumor ...
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COMPLEMENTARY THERAPEUTIC POTENTIAL: A FOCUS ON POLYHERBAL PRODUCTS IN HYPERGLYCEMIA
... available therapeutic options many herbal medicines have been recommended for the Treatment of diabetes medicinal plants have the advantage of having no side effects (Mohseni-Salehi et ...
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Sgo1 is a potential therapeutic target for hepatocellular carcinoma
... The idea of targeting cancer cells through the activation of spindle assembly checkpoint is being actively exploited. Vinca alkaloids block microtubule polymerization and thereby prevent the formation of a proper spindle ...
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Diabetes: Symptoms, Cause and Potential Natural Therapeutic Methods
... Diabetes mellitus has become a global disease and there is an ever increasing rate for diabetes worldwide due to sedentary lifestyle, unhealthy diet and excessive body weight. Insulin signaling pathway is the key pathway ...
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Assessment of antioxidant potential of Tinospora cordifolia (Stem extract) as a therapeutic strategy
... generating bacteria such as streptococci and pneumococci as well as by the phagocytic cells at the sites of bacterial infection (Yang et al., 2003). Glutathione -S-transferases (GSTs), is a cytosolic multifunctional ...
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The potential therapeutic value of therapist stuckness in systemic practice
... a therapeutic question in response to a feeling of “uncomfortableness” with the client group stories [Teresa: 10], brought into focus the subsumed voices, which comprised of the here-and-now experiencing-voices, ...
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Therapeutic potential of Tephrosia purpurea
... Tephrosia purpurea Linn. (Leguminoseae), commonly known in Sanskrit as Sharapunkha is a highly branched, sub-erect, herbaceous perennial herb. In Ayurvedic literature this plant has also given the name of “Sarwa ...
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The potential of deferasirox as a novel therapeutic modality in gastric cancer
... Recently, several studies have investigated the potential of deferasirox as an anti-neoplastic agent. Deferasirox has been reported to inhibit NF-κB activity in blood samples from patients with myelodysplastic ...
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