thiazolidin-4- ones
Synthesis and Antimicrobial Activity of 1-Thiazolidin-4-ones
... phenylpropanoyl)-3-(substituted aryl)-1-thiazolidin -4-ones, to each second step product (0.02mol) thioglycolic acid (0.03 mol) was mixed in dry benzene and the reaction mixtures were refluxed for 6h ...
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Synthesis and Evaluation of Some 2–Aryl–3–[Substituted Pyridin–2–Yl]-Amino/Methylamino Thiazolidin-4-Ones
... pyridin-2-yl]-amino/methylamino thiazolidin- 4-ones have been synthesized by cyclocondensation of [substituted pyridin-2-yl]-araldehydehydrazone and N-Methyl [substituted ...
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SYNTHESIS OF 3 (1 – BENZYL – 1H – BENZO [D] IMIDAZOL – 2 – L AMINO) – 2 – (3 – ARYL – 1 PHENYL – 1H – PYRAZOL – 4 – YL) THIAZOLIDIN – 4 ONES AND THEIR ANTIMICROBIAL ACTIVITIES
... 1h - Benzo [D] Imidazol – 2 - L Amino) – 2 - (3 – Aryl - 1- Phenyl - 1h - Pyrazol - 4 - Yl) Thiazolidin - 4- Ones (4a- f) in 41-65% yield. All the synthesized compounds were screened for ...
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2-ARYL-3-(5-PHENYL[1,2,4]TRIAZOLO[4,3-C]QUINAZOLIN-3-YL)-1,3-THIAZOLIDIN-4-ONES AS HCV NS5B RNA POLYMERASE INHIBITORS
... it was thought of interest to design and synthesize a novel series of 2-aryl-3-(5-phenyl[1,2,4]triazolo[4,3-c] quinazolin-3-yl)-1,3-thiazolidin-4-ones 4a-k that are structurally related to the ...
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SYNTHESIS AND CHARACTERIZATION OF VARIOUS 3 (6 SUBSTITUTED 3 HYDROXY 2,2 DIMETHYL 3,4 DIHYDRO 2HBENZOPYRAN 4 YL) 2 SUBSTITUTED 1,3 THIAZOLIDIN 4 ONES AND THEIR ANTIHYPERTENSIVE ACTIVITY
... The present work was aimed at exploring a series of novel 3-(6- substituted-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-benzopyran-4-yl)- 2-substituted-1,3-thiazolidin-4-ones by utilizing ...
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Synthesis and antibacterial screening of some 2 (p substituted benzylidene) 3 (5 ethyl 1,3,4 thiadiazol 2 yl)thiazolidin 4 ones
... Present study describes the synthesis of a series of 2-(p-substituted benzylidene)-3-(5-ethyl-1, 3, 4-thiadiazol-2-yl) thiazolidin-4-ones. The compounds were characterized by spectral ...
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Synthesis and antibacterial screening of some 2 (p substituted benzylidene) 3 (5 propyl 1, 3, 4 thiadiazol 2 yl) thiazolidin 4 ones
... The syntheses of 2-(p-substituted benzylidene)-3-(5-propyl-1, 3, 4-thiadiazol-2-yl) thiazolidin-4-ones were achieved following the steps outlined in the scheme. Reaction of compound 1 with ...
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Synthesis, Characterization and Antiproliferative Activity of Some Novel 2-(Substitutedphenyl)-5-Methyl-3-(Phenylamino)-1,3-Thiazolidin-4-Ones
... Chemotherapy is the primary therapeutic modality of treatment for the both localized and metastatic cancers. The newly synthesized 1,3-thiazolidin-4-one analogues (4a-g) at different concentration (10, 20, ...
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Synthesis and Antimicrobial Activities of Some New Azetidin-2-ones and Thiazolidin-4-ones
... thiazolidine-4-one (3a):1-β-[(N-benzenesulphonyl) anilino]propionylamido-2-(4-hydroxy)benzylidene hydrazine (2a, 4.23 g, 0.01 mol), thioglycoloic acid (0.9 g, 0.015 mol) in dry benzene was refluxed for 8–10 ...
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Synthesis and pharmacological evaluation of azetidin-2-ones and thiazolidin-4-ones encompassing benzothiazole
... Various 7-chloro-6-fl uoro-2-arylidenylaminobenzo(1,3)thiazole (2a-h) have been synthesized by the condensation of 7-chloro-6-fl uoro-2-aminobenzo(1,3)thiazole (1) with different aromatic aldehydes. The Schiff ’s bases ...
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Synthesis and Antimicrobial Activity of 2-(2- ketothiophen-yl)-3-(substituted aryl)- 5-{methylene-(4-haloaryl)}-1- thiazolidin-4-ones
... that 4-thiazolidinones possessing thiazole nucleus have been shown to have manifold biological activities such as antiviral, anti- HIV, anticancer, anticonvulsant, analgesic, anti- inflammatory, antihistaminic, ...
5
AN EFFICIENT, GREENER MICROWAVE ASSISTED MULTI COMPONENT ONE POT SYNTHESIS OF [1, 3, 4] THIADIAZIN 2 YL THIAZOLIDIN 4 ONES
... 3, 4] thiadiazin-2-ylamine 3(a-c) and [1, 3, 4] thiadiazin- 2-yl)- thiazolidin- 4- one 6(a-f) derivatives with excellent yield under microwave irradiation, which attains completion in 5 - 7 ...
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Antiinflammatory, analgesic and antipyretic activity of certain thiazolidinones
... for thiazolidin-4-one derivatives tested in the present study for having action similar to ...unsubstituted thiazolidin-4-ones and substitution at 5-position with spiro group did not ...
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Journal of Applied Pharmaceutical Science
... The ongoing spread of multidrug-resistant bacteria demands an intensive search for new antibacterial agents. In the present study, a series of new 1,3-thiazolidin-4-ones has been synthesized and ...
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Synthesis, characterization and antimicrobial activity of 2,3 disubstituted thiazolidin 4 one derivatives
... Various protocols are reported for the synthesis of thiazolidin-4-ones [1]. Basically it involves three component reactions of an amine, a carbonyl compound and a mercapto acid. These methods can be ...
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Synthesis of 5-arylidine-2-(3, 4, 5-trimethoxyphenyl)-3-(4-phenylthiazol-2-yl) Thiazolidin-4-one Derivatives as a Novel Class of Antimicrobial Agents
... 5~arylidine~2~(3, 4, 5~ trimethoxyphenyl)~3~(4~phenylthiazol~2~yl) thiazolidin~4~ones (5a-k) have showed some interesting antibacterial activity against bacterial strains ...compound ...
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Syntheses of New Thiazolidinones and Their Microbial Activity
... The acid hydrazide (I & IV) on condensation with different aromatic aldehydes yielded the substituted benzal hydrazines (IIa-e & Va-e) which on cyclization with thioglycolic acid in presence of anhydrous ...
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ANTI BACTERIAL ACTIVITY OF 3 (4 ARYL SUBSTITUTED 3 – YL) – THIAZOLIDIN 4 – ONE AND THEIR DERIVATIVES
... RESULTS AND DISCUSSION: Based on the literature review an attempt was made to synthesize some thiazolidin-4-one compounds by microwave oven. The antibacterial screening of the synthesized compounds were ...
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New synthetic uses for chiral 1,3 dioxolan 4 ones
... work continued on using simple and readily available α-amino and α-hydroxy acids to produce enantiomerically pure chiral precursors for the synthesis of natural products. This led them to investigate the electrophilic ...
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Thiazol-4-ones containing Azetidin-2-one
... A mixture of compound 7 (0.01mole) and triethylamine (0.1mole) was dissolved in 1,4-dioxane (10ml), kept in an ice bath, and stirred for 30 mins. To this, a cold solution of chloroacetyl chloride (0.01mole) was added ...
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