thiolated-chitosan
Thiolated chitosan modified PLA PCL TPGS nanoparticles for oral chemotherapy of lung cancer
... including thiolated chitosan-modified PCL nanoparticles, unmodified PLA-PCL-TPGS nanoparticles, and thiolated chitosan-modified PLA-PCL-TPGS ...characterized. Thiolated chitosan ...
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Thiolated chitosan nanoparticles as a delivery system for antisense therapy: evaluation against EGFR in T47D breast cancer cells
... Abstract: Thiolated chitosan has high transfection and mucoadhesive ...from chitosan-based particles while a lower and more sustained release of only 22% ± 8% was measured for thiolated ...
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Curcumin-incorporated Thiolated Chitosan/alginate Nanocarriers: Physicochemical Properties and Release Mechanism
... Herein, the development of thiolated chitosan (Cys-CS)/ALG NPs for curcumin delivery was reported, which could be used for colorectal cancer treatment. The mucoadhesive properties of Cys-CS could help ...
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Thiolated chitosan nanoparticles for enhancing oral absorption of docetaxel: preparation, in vitro and ex vivo evaluation
... of thiolated chitosan coated on poly methyl methacrylate cores as a carrier for oral delivery of ...both thiolated polymers and colloidal particles, these nanoparticles can be proposed as a drug ...
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Design, Characterization and Anti-ulcerogenic Effect of Amoxicillin trihydrate Thiolated Chitosan Mucoadhesive Microspheres for Effective Treatment of H. pylori
... loaded thiolated chitosan microspheres were prepared by emulsifying method using liquid paraffin light and heavy in ratio of 50:50 as a dispersing medium and glutaraldehyde used as a cross-linking ...the ...
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Synthesis of Novel N-Acyl Thiolated Chitosan Derivatives and their Assessment for Toxicity and Antimicrobial Activity in Vitro
... of chitosan at amino position results in increase in its water ...some chitosan conjugates with thiol containing moieties have shown swelling property in alkaline ...a Thiolated Chitosan ...
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Chemical coupling of thiolated chitosan to preformed liposomes improves mucoadhesive properties
... with thiolated chitosan, has been successfully synthesized and ...between chitosan-TGA and the ...with chitosan-TGA represents a promising strategy to create a mucoadhesive oral delivery ...
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THIOLATED CHITOSANS: A NOVEL MUCOADHESIVE POLYMERS: A REVIEW
... about thiolated chitosan which are gaining popularity because of their high mucoadhsiveness and extended drug release ...of chitosan with coupling reagents bearing thiol functions leads to the ...
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Chitosans Versus Thiolated Chitosans As Polymers In Mucoadhesive Drug Delivery - A Comparitive Study
... different thiolated chitosan derivatives have been synthesized: chitosan-thio glycolic acid conjugates, chitosan- cysteine conjugates and chitosan-4-thio-butyl-amidine ...
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Reducible Poly (2 Dimethylaminoethyl) Methacrylate Block Polyvinylimidazole: Synthesis, Transfection Activity in Vitro
... tant in gene delivery, for example, the transfection activity of thiolated chitosan was better than that of crossed-chitosan by disulfide bonds [29], the transfection efficiency of rPDMA[r] ...
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DEVELOPMENT OF THERMOGELLING HYDROGELS BASED ON A POLOXAMER 407 / CHITOSAN MIXTURE FOR SKIN APPLICATION
... / Chitosan mixtures. Thiolated or not for the treatment of certain skin ulcers like Buruli Ulcer after having synthesized 2- Iminothiolane or Thiobutylamidine (TBA), intermediate for the synthesis of ...
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Synthesis and characterization of thiolated hexanoyl glycol chitosan as a mucoadhesive thermogelling polymer
... nated thiolated polymers, that contain thiol functional moieties has been ...backbone, thiolated polymers have the ability to form a covalent disulfide bond with the mu- cous layer, leading to enhanced ...
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Peroral insulin delivery : new concepts and excipients
... as chitosan and its quaternized derivatives have been studied extensively for their role as multifunctional permeation enhancers to enhance the permeation of hydrophilic macromolecules in peroral drug ...delivery. ...
195
SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL STUDIES OF BIODEGRADABLE POLYMERS AND THEIR POLYMER METAL COMPLEXES
... Metal complexes of chitosan-salicylaldehyde polymer was prepared by using molar ratio (1:1) of the polymer and metal salts. The preparation of Cu(II) complex is carried out by dissolving 3.90 g(0.001 mol) of ...
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SYNTHESIS AND CHARACTERIZATION OF CHITOSAN (CS)/ CELLULOSE ACETATE (CA) /POLYVINYL ALCOHOL (PVA) TERNARY BLEND
... recycling of polymers and packaging. Polyvinyl alcohol (PVA) and its derivatives are hydrophilic and have reactive hydroxyl groups [11] and hence can be easily modified with other reactive functional groups to obtain ...
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PREPARATION, CHARACTERIZATION AND OPTIMIZATION OF THIOPECTIN BASED MUCOADHESIVE MICROSPHERES OF SALBUTAMOL SULPHATE
... using Thiolated Pectin polymers to enhance its stability and bioavailability and In-Vitro release of ...with Thiolated Pectin showed superior results compared to other ...
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Preparation of Chitosan Copper Complexes: Molecular Dynamic Studies of Chitosan and Chitosan Copper Complexes
... copper chitosan consists of Copper strip (anode) and Platinum strip (cathode) was immersed in the electrolytic solution suspended at a distance 5 cm from each other by Plati- num ...
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Functional aligned porous materials via directional freezing and frozen UV initiated polymerization
... Composite materials are defined as materials made up from two or more materials with different physical or chemical properties. When they are combined they produce a material with characteristics that are different from ...
175
High performance liquid chromatographic analysis of reduction products of a thiolated DNA for immobilization on gold nanoparticles
... usually thiolated and forms Au-S covalent bond to the surface of gold ...of thiolated DNAs that mostly employ Dithiothreitol ...a thiolated DNA with DTT is analyzed in this paper with high ...
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Application of Nanopore of Solid Membrane for Recognition of fluorescent Pseudomonas
... of an electrochemical immunosensor. Traditionally, electrochemical immunosensor were obtained by immobilizing the recognition element (either antibody or antigen) directly on the surface of the working electrode. To ...
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