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THIOPHENE RING

Synthesis and biological evaluation of pyridopyrimidinone derivatives containing thiophene ring as potential anti-inflammatory and antimicrobial agents

Synthesis and biological evaluation of pyridopyrimidinone derivatives containing thiophene ring as potential anti-inflammatory and antimicrobial agents

... In this study, certain 7-(Thiophen-2-yl)pyrido[2,3-d]pyrimidin-4(3H)-one derivatives were synthesized and evaluated for theirantimicrobial& anti-inflammatory activities. Results revealed that the compounds exhibited ...

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Design and synthesis of spiro derivatives containing a thiophene ring and evaluation of their Anti-microbial activity

Design and synthesis of spiro derivatives containing a thiophene ring and evaluation of their Anti-microbial activity

... displayed triplet at  3.83 ppm (J =10.6 Hz) due to benzylic proton (H-4) of pyrrolidine ring. The pyrrolidine ring proton of C-3 which is attached to the thiophenyl moiety appeared as a doublet at ´ 4.37 ( ...

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IN-VIVO ANTIMALARIAL STUDY OF PITC2 of Pluchea indica (L.) Less AGAINST Plasmodium berghei AND Plasmodium yolli MODEL

IN-VIVO ANTIMALARIAL STUDY OF PITC2 of Pluchea indica (L.) Less AGAINST Plasmodium berghei AND Plasmodium yolli MODEL

... PITC2 contains thiophene ring associated with three conjugated triple bond with one primary and one secondary hydroxyl group ( Figure 4c).. Based upon this point of evidence [r] ...

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(S) 2 (Meth­oxy­di­phenyl­methyl) 1 (thio­phen 3 yl­methyl)­pyrrolidine

(S) 2 (Meth­oxy­di­phenyl­methyl) 1 (thio­phen 3 yl­methyl)­pyrrolidine

... The assignment of the S absolute con®guration was based on our knowledge of the absolute con®guration of the starting material, (S)- proline, plus the fact that the synthesis reactions were such as to leave this ...

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2 Acetyl­phenyl 5 methyl­thio­phene 2 carboxyl­ate

2 Acetyl­phenyl 5 methyl­thio­phene 2 carboxyl­ate

... thiophene ring with the methyl C atom and carboxylate group (maximum deviation 0.041 AÊ; fragment A), the oxyphenyl ring with the central acetyl C atom (0.029 AÊ; B), and the acetyl group together ...

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(2E,7E) 2,7 Bis[(thio­phen 2 yl)methyl­­idene]cyclo­hepta­none

(2E,7E) 2,7 Bis[(thio­phen 2 yl)methyl­­idene]cyclo­hepta­none

... The title compound (Scheme 1, Fig. 1) crystallizes in the orthorhombic space group Pbcn. It has an E configuration with respect to the C6=C7 bond on both sides of the cycloheptanone ring. The central moiety ...

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(2E,4E) 8 Methyl 2,4 bis­(3 thienylmethyl­ene) 8 aza­bi­cyclo­[3 2 1]octan 3 one

(2E,4E) 8 Methyl 2,4 bis­(3 thienylmethyl­ene) 8 aza­bi­cyclo­[3 2 1]octan 3 one

... the thiophene rings on both sides of the tropinone ...the thiophene rings from the plane of the double bonds connecting the ...the thiophene ring π -electron systems with the C2═C6 double bond ...

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Design, synthesis, and biological activity of diaryl ether inhibitors of Toxoplasma gondii enoyl reductase

Design, synthesis, and biological activity of diaryl ether inhibitors of Toxoplasma gondii enoyl reductase

... the thiophene ring was carboxyl (16), which did not produce an effective inhibitor like the similar compound ...the thiophene-based inhibitors is compound 18 which showed a good inhibitory effect in ...

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Therapeutic importance of synthetic thiophene

Therapeutic importance of synthetic thiophene

... Madhavi et al. [34] developed a novel class of substi- tuted 2-(2-cyanoacetamido)thiophenes by cyanoa- cetylation of substituted 2-aminothiophene by using an effective cyanoacetylating agent, 1-cyanoacetyl- ...

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3,3,4,4,5,5 Hexa­fluoro 1 [2 methyl 5 (2 fluoro­phen­yl) 3 thien­yl] 2 (2 methyl 5 phenyl 3 thien­yl)cyclo­pent 1 ene, a new photochromic dithienylethene

3,3,4,4,5,5 Hexa­fluoro 1 [2 methyl 5 (2 fluoro­phen­yl) 3 thien­yl] 2 (2 methyl 5 phenyl 3 thien­yl)cyclo­pent 1 ene, a new photochromic dithienylethene

... planar thiophene ring systems have essentially identical geometry, and the dihedral angles between the central cyclopent-1-ene ring and the thiophene rings are ...

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The ethyl tetra­ester of ranelic acid

The ethyl tetra­ester of ranelic acid

... The bond lengths in the ring are comparable to those found in a single thiophene ring (Xu et al., 1998). The C1 C2 and C3 C4 distances (Table 1) show that they are C C double bonds (Zeng et al., ...

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Crystal structure of [4 (2 meth­­oxy­phen­yl) 3 methyl 1 phenyl 6 tri­fluoro­methyl 1H pyrazolo­[3,4 b]pyridin 5 yl](thio­phen 2 yl)methanone

Crystal structure of [4 (2 meth­­oxy­phen­yl) 3 methyl 1 phenyl 6 tri­fluoro­methyl 1H pyrazolo­[3,4 b]pyridin 5 yl](thio­phen 2 yl)methanone

... thiophene ring facilitates one of its ring C atoms to participate in the lone intermolecular C—H O hydrogen bond present in the crystal, leading to a characteristic C(5) chain graph-set motif linking ...

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Vol 6, No 6 (2017)

Vol 6, No 6 (2017)

... Thienopyrimidines derivatives continue to attract great interest due to the wide variety of interesting biological activities observed for compounds characterized by this heterocyclic system. This review results from the ...

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Electropolymerization of Thiophene on Stainless Steel and using for
Anticorrosion

Electropolymerization of Thiophene on Stainless Steel and using for Anticorrosion

... the thiophene unit, this peak missing in PT which implied that the thiophene unit was stable through the free radical electropolymerization and also shown that the electropolymerization happened at the ...

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Application of density functional theory in the synthesis of electroactive polymers

Application of density functional theory in the synthesis of electroactive polymers

... In the case of E-2-styrylthiophene XI, the highest spin population is located at the 5-position of the thiophene ring 0.211, although both 1”- and 2”-carbon atoms of the alkene spacer li[r] ...

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Di­methyl 1 (4 methyl­phen­yl) 8 (thio­phen 2 yl) 11 oxatri­cyclo­[6 2 1 02,7]undeca 2,4,6,9 tetra­ene 9,10 di­carb­oxy­late

Di­methyl 1 (4 methyl­phen­yl) 8 (thio­phen 2 yl) 11 oxatri­cyclo­[6 2 1 02,7]undeca 2,4,6,9 tetra­ene 9,10 di­carb­oxy­late

... six-membered ring adopts a boat conformation. The thiophene ring is disordered over two sets of sites with an occupancy ratio of ...4-methylphenyl ring and the major and minor components of ...

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Molecular and electronic structure of several 2,3 dithienylquinoxalines and their 2:1  complexes with silver(I) nitrate

Molecular and electronic structure of several 2,3 dithienylquinoxalines and their 2:1 complexes with silver(I) nitrate

... The HeI (21.2 eV) PE spectra for the three ligands are shown in Figure 3. We observe a noticeable difference in relative energies of the first peak of 1 in comparison with spectra of 2 and 3. This shift from 7.9 eV (for ...

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Design of co-crystals/salts of some Nitrogenous bases and some derivatives of thiophene carboxylic acids through a combination of hydrogen and halogen bonds

Design of co-crystals/salts of some Nitrogenous bases and some derivatives of thiophene carboxylic acids through a combination of hydrogen and halogen bonds

... involved in two one point supramolecular heterosyn- thons (Scheme 2c): one with the protonated nitrogen atom of trimethylene dipyridinium (N1-H1A…O2 = 2.5883(19)Å), a second with the adjacent carboxylic acid molecule ...

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Reaction of cis–[RuCl2 (DMSO)4 with some Aromatic Thioamides (RCSNHCOR’) in Presence Nitric Oxide and Pyridine

Reaction of cis–[RuCl2 (DMSO)4 with some Aromatic Thioamides (RCSNHCOR’) in Presence Nitric Oxide and Pyridine

... pyrrole ring (235 and 345 nm), substituted thiophene ring (295, 270 nm) and substituted benzene ring (260 nm) were present in the electronic spectra of (ETH, EPH, ATH, PTH), ESH and (CTH, PTH) ...

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Green Synthesis, Characterization, Photophysical and Electrochemical Properties of Bis-chalcones

Green Synthesis, Characterization, Photophysical and Electrochemical Properties of Bis-chalcones

... and thiophene bis-chalcones where ...and thiophene bis- chalcones were calculated front the onset oxidation potential of cyclic ...of thiophene bis-chalcone lies at ...and thiophene ...

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