THIOUREA DERIVATIVES
SYNTHESIS, PHARMACOLOGICAL EVALUATION AND LIGAND-PROTEIN INTERACTION STUDY OF HYBRID UREA AND THIOUREA DERIVATIVES AS ANTIHYPERGLYCEMIC AGENTS
... urea/thiourea derivatives were binding to the active site of α-glucosidase enzyme with the hydrophobic interactions, noncovalent and hydrogen bond ...
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Design, Synthesis and Bioevaluation of New Urea/Thiourea Derivatives of 3,5 dichloro 4 hydroxy aniline
... The antifungal strains, Aspergillus niger, Candida albicans and Fusarium oxysporum were used to investigate antifungal potency of the newly synthesized urea and thiourea derivatives 3(a-j) using the agar ...
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Design, Synthesis, and Docking Study of Acyl Thiourea Derivatives as Possible Histone Deacetylase Inhibitors with a Novel Zinc Binding Group
... acyl thiourea derivatives (4 and 5) was achieved successfully starting from adipic acid (4a) and pimelic acid (5a) ...acyl thiourea functionality as a ...
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Corrosion Inhibitive Effect of Synthesized Thiourea Derivatives on Mild Steel in a 15% HCl Solution
... synthesized thiourea derivatives, namely, 1-(3- mercapto-5-(pyridin-4-yl)-4H-1,2,4-triazol-4-yl)-3-phenylthiourea (MPTP), 1-(3-mercapto-5-(pyridin- 4-yl)-4H-1,2,4-triazol-4-yl)-3-(4-methoxyphenyl) ...
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Synthesis and antimicrobial evaluation of urea and thiourea derivatives of sulfonic acid
... and thiourea derivatives are known to posses various pharmacodynamic applications as antibacterial [21], antifungal [22], anticancer [23], antiinflammatory [24], antiviral [25], potent inhibitors of ...
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Synthesis and Preliminary Inhibition Study of Carbonyl Thiourea Derivatives on Corrosion of Mild Steel in Acidic Media
... of thiourea is the best organic compound that can be used as corrosion ...carbonyl thiourea derivatives as shown in Figure 1 and to investigate their inhibition efficiency on corrosion of mild steel ...
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Synthesis, docking study and biological evaluation of some new thiourea derivatives bearing benzenesulfonamide moiety
... The molecular model of the new thiourea derivatives was done using MOE software suite 10.2008. Follow- ing geometry optimization, a systematic conformational search was carried out to RMS gradient of 0.05 Å ...
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Synthesis, Identification, Theoretical And Experimental Studies For Carbon Steel Corrosion Inhibition in Sea Water for New Urea and Thiourea Derivatives linkage to 5 Nitro Isatin Moiety
... 5-Nitroisatin derivatives (1-4) was found to be effective inhibitors for carbon steel corrosion in ...Isatin derivatives possess a wide range of biological activities, therefore, they used as a safety and ...
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TREATMENT OF THYROTOXICOSIS IN CHILDREN WITH THIOUREA DERIVATIVES
... obvious reason. She was then given methylthiouracil, 300 mg. In spite of the large doses thyrotoxicosis persisted. Furthermore, the thyroid had increased in size. Methylthiouracil was di[r] ...
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Synthesis and Characterization of Some New Derivatives of Thiourea and Study of Their Biological Activity
... of thiourea functionality [1]. Thiourea, having a considerably wide range of applications ...and thiourea differ significantly because of the difference in electronegativity between sulfur and ...
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SYNTHESIS, SPECTRAL CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF NOVEL UREA/THIOUREA DERIVATIVEST. Narasaiah, C*. NagarajuDOWNLOAD/VIEW
... and thiourea derivatives had been discovered which exhibited broad spectrum of biological activities such as herbicidal [4], inhibition of nitric oxide [5], anti-viral [6] and analgesic properties ...and ...
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Synthesis and Antibacterial Activity of Urea and hiourea Derivatives at C 8 Alkyl Chain of Anacardic Acid Mixture Isolated from a Natural Product Cashew Nut Shell Liquid (CNSL)
... screened for their antibacterial activity [27] against some of the pathogenic bacteria viz. E. coli (MTCC443), P. aeruginosa (MTCC424), S. aureus, (MTCC96) and S. pyogenes (MTCC443) using agar well diffusion method ...
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DOCKING, SYNTHESIS AND CYTOTOXIC TEST ON HUMAN BREAST CANCER CELL LINE T47D OF N (PHENYLCARBAMOTHIOYL) BENZAMIDE
... and thiourea derivatives which is more lipophilic with better membrane penetration so that its activity is more ...of thiourea derivatives, as 1-(4-acetamidophenyl)-3-(4-tert- butylbenzoyl) ...
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Synthesis of Thiazole and Oxazole Derivatives by Organic Clay as a Novel Method and their Biological Evaluation
... thiazolane derivatives have been synthesized using activated acetylenic compounds and thiourea derivatives ...oxazole derivatives were prepared from condensation of bromo trimethoxyphenyl ...
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Therapeutic Aspects of Sulfonylureas: A Brief Review
... Mahdavi M et al, synthesized a series of 3-aroyl-1-(4-sulfamoylphenyl)thiourea derivatives containing sulfonamide moiety as 15-lipoxygenase (15-LOX) inhibitors. The most potent compound (3- methyl benzoyl ...
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A comparative study of the metal binding behavior of alanine based bis-thiourea isomers
... then, thiourea compounds have extensively been used as the building blocks of hetero- cyclic analogues ...benzoyl derivatives of thiourea have gained a great deal of importance in the present ...day. ...
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SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME METHYL 4 (1H BENZO[d] IMIDAZOL 2 YL) PHENYL CARBAMODITHIOATE AMINE DERIVATIVES
... benzimidazole thiourea derivatives show moderate to high degree of antimicrobial as well as antifungal activity, but no one is better than standard drug norfloxacin and ...nitrophenyl) thiourea shows ...
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“COMPARATIVE STUDY OF MICROWAVE AND CONVENTIONAL SYNTHESIS AND PHARMACOLOGICAL ACTIVITY OF PYRIMIDINES: A REVIEW” by Chandak Shilpa, Sharma Dipak, Sharma Vimukta, Dubey Arti, India.
... Chalcone derivatives are important starting materials for the synthesis of different classes of heterocyclic compounds such as pyrazolines, thiophenes and pyrimidines, ...
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QSAR Studies of Thiourea, Thiazolidinedione and Thioparabanic Acid Derivatives of 4-Aminoquinoline as Antimalarial Agents
... some thiourea, thiazolidinedione and thioparabanic acid derivatives of 4-aminoquinoline required for antimalarial activity and to obtain predictive two- and three-dimensional (2D and 3D) QSAR models, which ...
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Vol 8, No 9 (2019)
... 3,4-dihydropyrimidin-2(1H)-thione derivatives from aldehydes, ethyl acetoacetate and urea or thiourea using glycerol as an organo OH-acid, green and reusable catalyst is ...
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