THP-1 cells
Curcumin induces the apoptosis of human monocytic leukemia THP 1 cells via the activation of JNK/ERK Pathways
... THP1 cells (Figures 3B, 4D and 5), suggesting the tumor suppressor role of c-Jun and JunB in THP-1 ...induces THP-1 apoptosis via the activation of ERK/JNK path- ways and its downstream ...
8
Acanthamoeba castellanii (genotype T4) stimulates the production of interleukin-10 as well as pro-inflammatory cytokines in THP-1 cells, human peripheral blood mononuclear cells and human monocyte-derived macrophages
... Here, THP-1 cells, primary hu- man monocytes isolated from peripheral blood, and human monocyte-derived macrophages were either coincubated with tro- phozoites of a clinical isolate of Acanthamoeba ...
10
Metabolomic profiling of the immune stimulatory effect of eicosenoids on PMA-differentiated THP-1 cells
... In order to gain a comprehensive overview, further analysis was also carried out on the non-polar lipophilic metabolites in the cells using a reversed phase (RP) column. As shown in Figure 8A, PCA was employed for ...
26
Human amnion mesenchymal cells inhibit lipopolysaccharide-induced TNF-α and IL-1β production in THP-1 cells
... inflammatory cells associated with the pathologic process of inflammation ...of THP-1 cells, an immortalized human monocyte/macrophage cell line, to lipopolysaccharide (LPS) challenge as an ...
8
Release of human immunodeficiency virus by THP-1 cells and human macrophages is regulated by cellular adherence and activation.
... Ten days after infection with HIV-1RF, THP-1 cells were washed three times in PBS to remove all cell-free virus, resuspended in fresh medium, and cultured in nonadherent conditions in ti[r] ...
7
<p>CD40L inhibits cell growth of THP-1 cells by suppressing the PI3K/Akt pathway</p>
... T cells (purchased from Hlkbio ...of cells: THP-1 cells, NC-LV THP-1 cells, and CD40L-LV THP-1 cells (unless otherwise ...
7
Mono-ethylhexyl phthalate stimulates prostaglandin secretion in human placental macrophages and THP-1 cells
... immune cells can be important sources of uterotonic prostaglandins [36], the objective of the current study was to determine the influence of MEHP, a principle bioactive metabolite of DEHP, on prosta- glandin ...
8
Phagocytosis of hemozoin by RAW 264.7 cells, but not THP-1 cells, promotes infection by Leishmania donovani with a nitric oxide-independent mechanism
... blood cells, and rapidly phagocytized by host mononuclear ...PMA-differentiated THP-1 cells previously exposed to increasing amounts of HZ or its synthetic analogue -hematin ...264.7 ...
40
Evidence that HIV 1 restriction factor SAMHD1 facilitates differentiation of myeloid THP 1 cells
... treating THP-1 cells with ...T cells, which transit from a quiescent state to a dividing state following ...T cells in a quiescent ...T cells would delay entry into cell cycle ...
6
Effect of melittin on metabolomic profile and cytokine production in PMA-differentiated THP-1 cells
... Understanding the process of macrophage activation by LPS is important for the identification of suitable immune stimulators, and these metabolic shifts could therefore be useful in this type of research. Macrophages ...
21
Treating cancer stem cells and cancer metastasis using glucose-coated gold nanoparticles
... for THP-1 cells 36 hours, 60 hours, and 84 hours after irradiation, respec- ...killing THP-1 cells than MCF-7 ...MCF-7 cells, but the treatment effectiveness of Glu-GNP ...
13
HCV core protein binds to gC1qR to induce A20 expression and inhibit cytokine production through MAPKs and NF-κB signaling pathways
... HCV core protein was successfully expressed and purified, and proved to be a single band by SDS-PAGE and Western blot (Figure 1A). The protein contained 3 EU/mL of endotoxin and was quantified as 0.5 mg/mL by Bradford ...
13
APOC3 induces endothelial dysfunction through TNF-α and JAM-1
... JAM-1 is localized in and is an important component of the TJs in ECs. It mainly influences cell-cell adhesion. Moreover. JAM-1 was associated with the process of ex- udation, which is significant in AS. ...
8
Monocytes exposed to plasma from patients with Alzheimer's disease undergo metabolic reprogramming
... incubate THP-1 cells, a human monocyte cell line, with plasma from control, MCI and AD cohorts and assess the impact of the plasma on inflammatory readouts and on the metabolic profile of ...
26
Elucidation mechanism of different biological responses to multi-walled carbon nanotubes using four cell lines
... (Figure 1(A) a, d, g, j and m; Figure 2A, D and G). BEAS-2B cells were only exposed to VGCF at 1 µ g/mL concentration because VGCF at 10 µ g/mL caused many cell deaths in BEAS-2B ...ated ...
11
Citrullination as early stage indicator of cell response to single walled carbon nanotubes
... lung cells, our data proved that phagocytic THP-1 cells were highly sensitive to all SWCNTs samples (Figure 2), responding to the SWCNTs exposure with high levels of secreted pro-inflammatory ...
7
Structure and function of the long terminal repeats of feline leukemia viruses derived from naturally occurring acute myeloid leukemias in cats.
... Enhancer function of URE. To examine the enhancer func- tion of the URE and its repetitive structure, CAT reporter plasmids were constructed. SacI-EcoRV fragments which con- tained URE (nt 1968 to 2159 in ...
5
I. Ion Channels in Human THP-1 Monocytes
... have been reported in human monocyte-derived macro- phages (Nelson, Jow & Jow, 1990a). In human neutro- phils, an outwardly-rectifying Cl − conductance is acti- vated by cell swelling (Stoddard, Steinbach & ...
14
Intracellular activity of tedizolid phosphate and ACH-702 versus Mycobacterium tuberculosis infected macrophages
... over THP-1 cells an assay for cytotoxicity was carried on. THP-1 cells were transformed to macrophages as described previously [18] and then incubated at concentrations 16X the ...
5
Characterization of the immunomodulatory properties of alveolar bone-derived mesenchymal stem cells
... − cells (which have a lower immunostimulatory capacity towards anti-inflammatory macrophage differentiation) ...of THP-1 monocytic cells or macro- phages with aBMSCs or BMSCs were carried out ...
13