THP-1 macrophages
Role of interleukin 1 beta in foam cell formation of THP 1 macrophages
... of THP-1 macrophages (Mфs). Human THP-1 monocytes were differentiated into macrophages by phorbol esters in vitro, then the macrophages were incubated with the absence of ...
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Effect of different concentrations of omega-3 fatty acids on stimulated THP-1 macrophages
... THP-1 macrophages. It is well accepted that EPA and DHA are associated with a lower risk of inflammatory diseases [7]. Their health effects are usually studied as a sum or combination. Thus, little ...
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Original Article Tanshinone IIA reduces oxidized low-density lipoprotein-induced inflammatory responses by downregulating microRNA-33 in THP-1 macrophages
... models. Macrophages-secreted pro-inflammatory factors play vital roles in the development of ...in THP-1 ...ox-LDL-stimulated THP-1 ...ox-LDL-stimulated THP-1 ...
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Enhanced uptake of multiple sclerosis-derived myelin by THP-1 macrophages and primary human microglia
... for THP-1 macrophages after 24 hours of incubation with ...by THP-1 macrophages after 24 hours of incubation with ...by THP-1 macrophages after 6 hours of ...
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Sulforaphane rescues amyloid-β peptide-mediated decrease in MerTK expression through its anti-inflammatory effect in human THP-1 macrophages
... attention as an alternative candidate for AD therapy due to its safety, efficacy, and blood–brain barrier penetration [14]. Indeed, sulforaphane can ameliorate the cognitive function of Aβ-induced AD acute mouse models ...
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The efficacy and mechanism of apoptosis induction by hypericin-mediated sonodynamic therapy in THP-1 macrophages
... Results: HY was sublocalized among the nuclei and the mitochondria, endoplasmic reticulum, Golgi apparatus, and lysosome in the cytosol of THP-1 macrophages. Under low-intensity ultrasound ...
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Attenuation of niacin-induced prostaglandin D<sub>2</sub> generation by omega-3 fatty acids in THP-1 macrophages and Langerhans dendritic cells
... Abstract: Niacin, also known as nicotinic acid, is an organic compound that has several cardio- beneficial effects. However, its use is limited due to the induction of a variable flushing response in most individuals. ...
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III. Ion Channel Expression in PMA-differentiated Human THP-1 Macrophages
... PMA-differentiated THP-1 macrophages ...in macrophages and related cells. Mouse peritoneal macrophages express I DR after one to four days in culture (Ypey & Clapham, 1984), which ...
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Caffeine Inhibits NLRP3 Inflammasome Activation by Suppressing MAPK/NF-κB and A2aR Signaling in LPS-Induced THP-1 Macrophages
... LPS-induced THP-1 macrophages were significantly reduced after pretreatment with ...in THP-1 macrophages by affecting MAPK/NF-κB signaling, in part by inhibiting A2aR-activated ...
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Apoptosis of THP-1 macrophages induced by protoporphyrin IX-mediated sonodynamic therapy
... necrotic THP-1 macrophages after PpIX-mediated SDT were determined by Hoechst 33342 and propidium iodide assay (A and B) and flow cytometry with double staining of Annexin V and propidium iodide ...
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Dual and Triple Epithelial Coculture Model Systems with Donor-Derived Microbiota and THP-1 Macrophages To Mimic Host-Microbe Interactions in the Human Sinonasal Cavities
... of THP-1- derived macrophages did not affect the growth of these bacterial ...donor 1, whereas for donor 2 a mild decrease in IL-8 levels was noted after 72 ...donor 1 derived ...
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Pepsin-pancreatin protein hydrolysates from extruded amaranth inhibit markers of atherosclerosis in LPS-induced THP-1 macrophages-like human cells by reducing expression of proteins in LOX-1 signaling pathway
... receptor 1 (LOX-1), leads to the expression of adhesion molecules such as intracellular adhesion molecule (ICAM), which is responsible for the monocytes adhesion to the endo- thelium ...
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Effect of n-3 fatty acids on the expression of inflammatory genes in THP-1 macrophages
... unstimulated macrophages, depending on the metabolic pathway of interest, the n-3 FA having the most import- ant effect is ...on macrophages were studied without induced inflamma- ...
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Mebendazole induced M1 polarisation of THP 1 macrophages may involve DYRK1B inhibition
... Previous studies have demonstrated that IL1β release require two signals. The first is provided by toll-like- receptor-mediated NF-kappaB activation whereas the second can be mediated by danger signals such as ...
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Original Article Ulinastatin reduces LPS-induced THP-1 macrophage M1-like characteristics
... type 1 macrophages (M1) when stimulated by lipopolysaccharide and proinflammatory ...μg/mL)-induced THP-1 ...transcription) 1, and STAT3 were detected by Western ...induced ...
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Human immunodeficiency virus type 1 envelope protein does not stimulate either prostaglandin formation or the expression of prostaglandin H synthase in THP-1 human monocytes/macrophages.
... 3, THP-1 monocytes did not significantly metabolize exogenous arachidonic ...the THP-1 cells with LPS, a known stimulator of PGHS-2 expression in macrophages, slightly enhanced pros- ...
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Intracellular Infections Enhance Interleukin-6 and Plasminogen Activator Inhibitor 1 Production by Cocultivated Human Adipocytes and THP-1 Monocytes
... of macrophages into adipose tissue, which in turn may exacerbate the inflammatory state in ...and THP-1 ...inhibitor 1 (PAI-1) were ...and THP-1 macrophages in a ...
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Eradication of intracellular Francisella tularensis in THP-1 human macrophages with a novel autophagy inducing agent
... of 1 - 5 μM ...human macrophages, THP-1 macrophages were exposed to 1 μM of AR-12, and then evaluated for evidence of autophagy by immunocytochemistry and Western blot ...human ...
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Metabolomic profiling of the immune stimulatory effect of eicosenoids on PMA-differentiated THP-1 cells
... Abstract: Honey bee venom has been established to have significant effect in immunotherapy. In the present study, (Z)-11-eicosenol-a major constituent of bee venom, along with its derivations methyl cis-11-eicosenoate ...
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Screening of compounds toxicity against human Monocytic cell line-THP-1 by flow cytometry
... As previously mentioned, we screened 36 initial compounds for disc sensitivity and MIC, Only the most promising seven compounds were chosen for further testing with the discussed assay. Different compounds within the ...
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