Thymic epithelial cells
Growth hormone in the presence of laminin modulates interaction of human thymic epithelial cells and thymocytes in vitro
... smaller thymic volume and diminished output of naive T-lymphocytes observed in GH deficiency children sug- gest that thymic function may be impaired in the pres- ence of defective GH ...human thymic ...
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Interferons Mediate Terminal Differentiation of Human Cortical Thymic Epithelial Cells
... 21). Thymic microen- vironments are composed of a network of thymic epithelial cells (TEC), present in both the cortex and the medulla, and hematopoietic cells such as macrophages and ...
10
Cbx4 regulates the proliferation of thymic epithelial cells and thymus function
... Thymic epithelial cells (TECs) are the main component of the thymic stroma, which supports T-cell proliferation and repertoire ...the thymic epithelium, has an essential and ...
9
Extensive RNA editing and splicing increase immune self representation diversity in medullary thymic epithelial cells
... and epithelial cell populations, including brain, testes, liver, kidney, lung, colon, skeletal muscle (skm), spleen, cortical thymic epithelial cells (cTECs), and skin epithelial ...
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Measles Virus Infection Induces Terminal Differentiation of Human Thymic Epithelial Cells
... dendritic cells (10, 14, ...49). Thymic stromal cells have been described as a target for MV in the SCID-hu mouse model after direct intrathymic inoculation of ...the thymic epithelial ...
10
High-Level Replication of Human Immunodeficiency Virus in Thymocytes Requires NF-κB Activation through Interaction with Thymic Epithelial Cells
... the cells permanently destroyed by the virus ...and thymic alterations including a profound disorganization of the epithelial network (28, 45, 47) and thymocyte ...with thymic ...
10
Contact with Thymic Epithelial Cells as a Prerequisite for Cytokine-Enhanced Human Immunodeficiency Virus Type 1 Replication in Thymocytes
... We report here that human immunodeficiency virus type 1 (HIV-1)-infected human thymocytes, in the absence of any exogenous stimulus but cocultivated with autologous thymic epithelial cells (TEC), ...
10
Gli3 in fetal thymic epithelial cells promotes thymocyte positive selection and differentiation by repression of Shh
... SP cells, followed by negative selection of potentially self-reactive clones (Klein et ...Those cells receiving stronger longer TCR signals tend towards the SP4 fate, weaker/more transient signals favour ...
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Persistent Infection of Human Thymic Epithelial Cells by Coxsackievirus B4
... confluent cells (TEC) were detached by treatment with a solution of trypsin-Versene (EDTA) (Bio- Whittaker, Verviers, Belgium) and filtered through nylon gaze to eliminate explant ...400,000 cells per T-25 ...
6
Foxa1 and Foxa2 in thymic epithelial cells (TEC) regulate medullary TEC and regulatory T cell maturation
... identi fi ed. Bar chart shows mean ± SEM of percentage of follicular B-cells and marginal zone B-cell for control (n = 4) and Foxa1/2Foxn1cKO (n = 4) spleen. (E) Dot plots show staining of anti-CD25 against ...
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Identification of human and rodent thymic epithelium using tetanus toxin and monoclonal antibody A2B5
... rodent thymic epithelial cells have been ...toxin-binding cells form a network of thymic epithelial cells throughout the thymic subcapsular cortex and thymic ...
7
Medullary thymic epithelial cell depletion leads to autoimmune hepatitis
... the thymic epithelium ...medullary thymic epithelial cells (cTECs and mTECs, ...T cells that recog- nize these antigens with high affinity ...
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Functional disruption of human leukocyte antigen II in human embryonic stem cell
... nucleated cells [9]. Constitutive HLA II molecules are expressed mainly on thymic epithelial cells and profes- sional APCs, including DCs, B-lymphocytes, monocytes and ...and epithelial ...
9
Novel approaches for immune reconstitution and adaptive immune modeling with human pluripotent stem cells
... of cells of the thymus from ES and iPS ...T cells, cells essential for adaptive ...an epithelial and a mesenchymal ...T cells and mature dendritic cells [5-7]. The ...
5
Thymic hyperplasia in patients with Graves' disease Identification of thyrotropin receptors in human thymus
... that thymic size and CT atten- uation values significantly increased in untreated patients with Graves’ disease in comparison with control subjects in all age groups ...examined. Thymic size and CT ...
8
Expression of pRb and p16INK4 in human thymic epithelial tumors in relation to the presence of human polyomavirus 7
... PRb and phosphoralized Rb (phospho-Rb) expression was detected by using two monoclonal Retinoblastoma anti- bodies: pRb (a.a. 332–344), clone G3-245, Pharmingen, dilution 1:300 and phospho-Rb, clone D20B12, dilution ...
6
Sonic Hedgehog regulates thymic epithelial cell differentiation
... on thymic epithelial cell (TEC) ...in thymic stroma, had increased numbers of TEC, but decreased cell surface expression of MHC Class II molecules on both cortical and medullary ...T cells in ...
12
Case Report IgG3 subclass-positive primary thymic MALT lymphoma without trisomy 3 and trisomy 18: report of a case and review of literature
... radic cells in the MALT lymphoma that showed a propensity for transformation into plasma cells were positive for IgG3 expression, but were negative for IgG1, IgG2 and ...plasma cells in the MALT lym- ...
8
Respiratory syncytial virus induces functional thymic stromal lymphopoietin receptor in airway epithelial cells
... 2 Thymic stromal lymphopoietin receptor (TSlPR) and interleukin-7 receptor-α (Il-7Rα) are not regulated by nuclear factor kappa-light-chain-enhancer of activated B cells ...A549 cells were ...
9
T cell selection in the thymus
... J^, to D^J^, and then to J^. Although mechanisms of V(D)J recombination remain largely unknown, the reaction is thought to involve recognition of conserved recombination signal (RS) sequences (heptamer-spacer-nonamer ...
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