thyroid transcription factor 1 (TTF1)
Comparison of napsin a versus thyroid transcription factor 1 in the typing of lung carcinoma
... VERSUS THYROID TRANSCRIPTION FACTOR-1 IN THE TYPING OF LUNG CARCINOMA” is the bonafide work done by me at the Institute of pathology, Madras Medical College under the expert guidance and ...
142
Partial deficiency of Thyroid transcription factor 1 produces predominantly neurological defects in humans and mice
... genes, TTF1, TTF2, and PAX8, involved in thyroid gland development and migration have been ...in thyroid dysgenesis gave essentially negative ...no TTF1 gene defects were found in 76 ...
6
Pathological transition as the arising mechanism for drug resistance in lung cancer
... carcinoma; TTF1: thyroid transcription factor-1; DNP63: delta N tumor protein 63; ASCL1: achaete-scute homologue 1; NCAM: neural cell adhesion molecule; SYP: synaptophysin; AT ...
13
Thyroid transcription factor-1 expression is significantly associated with mutations in exon 21 of the epidermal growth factor receptor gene in Chinese patients with lung adenocarcinoma
... patients with NSCLC for EGFR mutations status is crucial. However, the relationship between postoperative survival and EGFR mutation and/or TTF-1 expression has not been clearly elucidated. We found that ...
10
Expression of thyroid transcription factor-1 is associated with a basal-like phenotype in breast carcinomas
... (Figure 1). Three cases had a high TTF-1 expression with a staining index of 9 (2 cases), and 6 (1 case), while 4 cases had a low TTF-1 expression with a staining index of 3 (1 case) ...
6
Thyroid transcription factor-1 positive primary breast cancer: a case report with review of the literature
... The initial investigations of the biopsy gave suspicion of metastasis from lung cancer because of the positive TTF- 1 reaction. Previous studies have shown that lung cancer, malignant melanoma and lymphoma are the ...
5
Download Download PDF
... and thyroid transcription factor-1 (TTF-1) Immunohistochemical profile of a carcino- ma is known to be useful aid in ascertaining the site of origin of an ...specific ...
5
Value of thyroid transcription factor (TTF)-1 for diagnosis and prognosis of patients with locally advanced or metastatic small cell lung cancer
... Methods: We analyzed a total of 294 patients (m, n = 184; f, n = 110) with SCLC (stage IIIA, n = 32; IIIB, n = 87; IV, n = 175) diagnosed in our institution between January 2005 and December 2008. Patient ’ s ...
8
Coexistence of endometrial mesonephric-like adenocarcinoma and endometrioid carcinoma suggests a Müllerian duct lineage: a case report
... approximately 1% of endo- metrial carcinomas, but appear to be aggressive in na- ture [3, ...for thyroid transcription factor 1 (TTF-1), GATA binding protein-3 (GATA-3), and ...
6
Congenital human thyroglobulin defect due to low expression of the thyroid specific transcription factor TTF 1
... are thyroid-specific transcription factors, from homeo and paired box genes, respectively, that are responsible for thyroid development and for thyroglobulin and thyroperoxidase gene ...the ...
6
Differential expression of two activating transcription factor 5 isoforms in papillary thyroid carcinoma
... Activating transcription factor 5 (ATF5) is a member of the activating transcription/cAMP response element-binding protein family of basic leucine zipper proteins that plays an important role in cell ...
7
Thyroid transcription factor FOXE1 interacts with ETS factor ELK1 to co-regulate TERT
... Next we examined by ChIP whether FOXE1 and ELK1 were co-bound to the human TPO promoter, in a region orthologous to the well-characterized FOXE1- responsive element in the rat TPO promoter (–177 to –23 bp relative to the ...
15
Subclinical Thyroid Dysfunction and Fracture Risk: A Meta-analysis
... cohorts, thyroid function was assessed at baseline only, which is a limitation of most published large cohorts on the risk of subclinical thyroid ...overt thyroid dysfunction, 51 while 15% to 65% ...
22
Sirtuin 1 Regulates Hepatitis B Virus Transcription and Replication by Targeting Transcription Factor AP-1
... amined in HepG2.2.15 and HepG2-HBV1.1 cells. Downregula- tion of SIRT1 resulted in decreased levels of HBV DNA replicative intermediates, as evidenced by both real-time PCR (Fig. 2B) and Southern blotting (Fig. 2C). The ...
10
Human T-Cell Leukemia Virus Type 1 (HTLV-1) bZIP Factor Requires Cellular Transcription Factor JunD To Upregulate HTLV-1 Antisense Transcription from the 3′ Long Terminal Repeat
... ATF/CREB transcription factors are ubiquitously ex- pressed in mammalian cells (51), the expression of AP-1 tran- scription factors is regulated by the cell activation status (9, 21, ...activate ...
9
Dysfunction of various organelles provokes multiple cell death after quantum dot exposure
... CdSe QDs were respectively functionalized with mercapto- propionic acid (MPA) and cysteamine (CYST). The charge of MPA-CdSe QDs is negative and that of CYST-CdSe QDs is positive. Both types have similar size. ...
14
The significance of alternative transcripts for Caenorhabditis elegans transcription factor genes, based on expression pattern analysis
... distinct transcription factor isoforms would be generated if alternative transcripts arose from inclusion versus exclusion of optional introns or ...a transcription factor ...for ...
36
Pharmacological inhibition of the transcription factor PU 1 in leukemia
... Comparison of PU.1 ChIP-seq of vehicle versus DB2313 treatment as the background showed a strong enrichment of PU.1 motifs, while the opposite comparison showed enrichment of motifs that are not related to ...
18
Protein-protein interactions of transcription factor CREB 1
... As discussed in Chapter 1, undifferentiated F9 cells show typically low levels of transcriptional responses to signals which elicit responses in other cell lines. The somatostatin CRE cannot be activated in ...
197
Direct, Interferon-Independent Activation of the CXCL10 Promoter by NF-κB and Interferon Regulatory Factor 3 during Hepatitis C Virus Infection
... CXCL10 transcription during HCV infection as well as following exposure to poly(I·C) (a Toll-like receptor 3 [TLR3] stimulus) and 5= poly(U) HCV RNA (a retinoic acid-inducible gene I [RIG-I] stimulus) from two ...
9