tight junction
Ischemia induced loss of epithelial polarity Role of the tight junction
... in tight junction penetration by ruthenium red to 29, 50, and 62%, ...tubule tight junctions open, which in turn leads to the lateral intramembranous diffusion of membrane components into the ...
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Tricellulin deficiency affects tight junction architecture and cochlear hair cells
... mutations and further demonstrates the biological significance of tricellulin in regulating the paracellular barrier in the organ of Corti and other body organs. The phenotypic changes observed in the other organs of the ...
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Regulation of tight junction barrier function by phospholipase C
... first tight junction protein identified, it is the claudin family of proteins that are believed to constitute the primary physical components of tight junctions 40, 41 ...between tight ...
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Overexpression of caveolin-1 attenuates brain edema by inhibiting tight junction degradation
... Cerebral edema from the disruption of the blood-brain barrier (BBB) after cerebral ischemia is a major cause of morbidity and mortality as well as a common event in patients with stroke. Caveolins (Cavs) are thought to ...
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Expression of Claudin Tight Junction Proteins in Response to Varying Environmental and Physiological Conditions.
... homeostasis. Tight junctions are specialized, multi-component structures located at the most apical side of lateral cell membranes ...2008). Tight junctions are responsible for the sealing the spaces ...
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Original Article Tight junction proteins and gap junction proteins play important roles in high fat dietary atherosclerosis pathogenesis
... of Tight Junction formed ...gap junction and tight junction loss could further strengthen the abili- ty of paracellular permeability even in ...
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Role of tight junction proteins in gastroesophageal reflux disease
... of tight junction-related molecules (transcript level) does not correlate with histomorphological changes in esophageal mucosa In order to study potential correlations between gene expression levels ...
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Tight Junction Protein Occludin Is a Porcine Epidemic Diarrhea Virus Entry Factor
... the tight junction protein occludin contrib- utes to PEDV infection and acts as an entry ...the tight junction protein occludin as a coreceptor to infect polarized epithelium ...
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Clostridium difficile toxin A perturbs cytoskeletal structure and tight junction permeability of cultured human intestinal epithelial monolayers
... damage at the time the maximum resistance response was observed. Fluorescent staining for F actin, however, revealed a marked decrease in fluorescent intensity in toxin-treated monolayers versus controls. These data show ...
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Original Article Somatostatin regulates tight junction proteins expression in colitis mice
... stimulated tight junction protein expression in these ...on tight junction is ...colonic tight junction protein expression in colitis ...
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Tight junction disruption by cadmium in an in vitro human airway tissue model
... TJ: Tight junction; ALI: Air-liquid-interface; TEER: Trans-epithelial electrical resistance; PKC: Protein kinase C; ZO-1: Zonula occludens-1; NHBE: Normal primary human bronchial epithelial; TJAP1: ...
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An emerging role for IQGAP1 in tight junction control.
... adherens junction forma- tion through sequestering E-Cadherin from cell-cell con- ...of tight junction proteins such as ZO-1 and clau- ...of tight junction ...
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Cinnamicaldehyde regulates the expression of tight junction proteins and amino acid transporters in intestinal porcine epithelial cells
... Tight junction (TJ) proteins are vital for the maintenance of intestinal epithelial barrier function, transport, absorption and utilization of dietary amino acids and other nutrients.. I[r] ...
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Analysis of Xenopus laevis claudin (Xcla) Tight Junction Genes in Development
... Cell differentiation, migration, cell-cell communication and epithelial-mesenchymal transition (EMT) are basic events during embryogenesis. Claudin 6 affects epidermal cell differentiation (Turksen and Troy, 2002a) and ...
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Tight junction structure, function, and assessment in the critically ill: a systematic review
... Background: Epithelial and endothelial barrier integrity, essential for homeostasis, is maintained by cellular boarder structures known as tight junctions (TJs). In critical illness, TJs may become disrupted, ...
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Claudin-12 is not required for blood–brain barrier tight junction function
... Since we could not readily identify prominent clau- din-12 expression in brain endothelial cells by detection of lacZ reporter activity, we attempted to identify clau- din-12 protein ex[r] ...
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Prostaglandin induced cervical remodelling in humans in the first trimester is associated with increased expression of specific tight junction, but not gap junction proteins
... as junction adhesion molecules, occludin and claudins ...Gap Junction (GJ) proteins, namely Connexins (Cx) 43, 26 and 30 in human cervical ectothelium has been described [23,24], but whether they play a ...
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Prostaglandin-induced cervical remodelling in humans in the first trimester is associated with increased expression of specific tight junction, but not gap junction proteins
... elucidated. Tight junctions (TJ) and gap junctions (GJ) regulate paracellular and intercellular solute transport respectively but their role in the process of CR remains ...
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A Protein Kinase A-Dependent Mechanism by Which Rotavirus Affects the Distribution and mRNA Level of the Functional Tight Junction-Associated Protein, Occludin, in Human Differentiated Intestinal Caco-2 Cells
... There was a decrease in the nonphosphorylated form of the protein in both the detergent-soluble and detergent-insoluble fractions of RRV-infected Caco-2 cells. It has been reported that the loss of occludin in Vibrio ...
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Extracorporeal shockwave against inflammation mediated by GPR120 receptor in cyclophosphamide-induced rat cystitis model
... 8 Inflammatory cells infiltration and urothelial tight junction integrity of urinary bladder in rats following cyclophosphamide (CYP) stimulation with and without GPR120 agonist / extrac[r] ...
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